Head and Neck Squamous Cell Carcinoma Clinical Trials in Winston-Salem, North Carolina

4 studies are recruiting for head and neck squamous cell carcinoma in Winston-Salem, North Carolina right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

    Phase I Study of NT-175, an autologous T cell therapy product genetically engineered to express an HLA-A*02:01-restricted T cell receptor (TCR), targeting TP53 R175H mutant malignancies

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Research Site, Winston-Salem, North Carolina
    Locations
    23 in total
    Run by
    AstraZeneca

    See if you can join NCT05877599 on ClinicalTrials.gov

  2. Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

    This phase II trial compares the effectiveness of adding BMX-001 to usual symptom management versus usual symptom management alone for reducing oral mucositis in patients who are receiving chemoradiation for head and neck cancer. Oral mucositis (inflammation and mouth sores) is a common side effect…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Wake Forest University Health Sciences, Winston-Salem, North Carolina
    Locations
    153 in total
    Run by
    NRG Oncology

    See if you can join NCT06532279 on ClinicalTrials.gov

  3. Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

    This is a Phase II treatment, non-randomized, open label clinical trial to study the efficacy of the Cetuximab when administered as single agent in recurrent/ metastatic head and neck squamous cell carcinoma after the failure or intolerance of immuno-oncology or immuno-oncology combined with chemot…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina
    Run by
    Wake Forest University Health Sciences

    See if you can join NCT04375384 on ClinicalTrials.gov

  4. A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

    This is a Phase 3 randomized, open-label study to evaluate the efficacy and safety of petosemtamab plus pembrolizumab vs pembrolizumab in first-line treatment of recurrent or metastatic PD-L1+ head and neck squamous cell carcinoma.

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Site 118, Winston-Salem, North Carolina
    Locations
    205 in total
    Run by
    Merus B.V.

    See if you can join NCT06525220 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.