Head and Neck Cancer Clinical Trials in Baltimore, Maryland

6 studies are recruiting for head and neck cancer in Baltimore, Maryland right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

   This is a proof-of-concept study designed to investigate HER3-DXd monotherapy in locally advanced unresectable or metastatic solid tumors. The study is enrolling cohorts of participants with melanoma [cutaneous/acral], squamous cell carcinomas of the head and neck (SCCHN), HER2-negative gastric can…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Johns Hopkins University, Baltimore, Maryland

   Locations

   90 in total

   Run by

   Daiichi Sankyo

   See if you can join NCT06172478 on ClinicalTrials.gov

2. Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer

   Background: Cisplatin is used to treat head and neck cancer. People who take this drug are at risk for hearing loss. Atorvastatin is a drug used to treat high cholesterol. It might reduce the risk of cisplatin-induced hearing loss. Objective: To find out if atorvastatin reduces hearing loss in peop…

   Stage

   Phase 2

   Ages

   18 to 100

   Site

   University of Maryland Medical Center, Baltimore, Maryland

   Locations

   5 in total

   Run by

   National Institute on Deafness and Other Communication Disorders (NIDCD)

   See if you can join NCT04915183 on ClinicalTrials.gov

3. Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

   This research is being done to collect and store biological specimens (biospecimens) from people with cancer, regardless of tumor type, who are receiving treatments known or thought to have an effect on the immune system. The goal of this discovery and exploratory study is to: * Understand changes …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Johns Hopkins University, Baltimore, Maryland

   Run by

   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

   See if you can join NCT05995821 on ClinicalTrials.gov

4. Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients

   The goal of this trial is to determine whether it is possible to minimize radiation dose to parts of the brain that are important for thinking and learning in children who require radiation to treat their tumor, and if this will help reduce neurocognitive (thinking and learning) impairments in thes…

   Stage

   Not phased

   Ages

   1 to 26

   Site

   Johns Hopkins Hospital, Baltimore, Maryland

   Locations

   2 in total

   Run by

   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

   See if you can join NCT05658731 on ClinicalTrials.gov

5. Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

   The NeoScorch HN study is a single institution multisite phase II trial including 3 cohorts of 25 patients each for patients with newly diagnosed locoregionally advanced, histologically confirmed, head and neck cancer eligible for curative-intent treatment, who will receive neo-adjuvant chemoimmuno…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Johns Hopkins Hospital East Baltimore, Baltimore, Maryland

   Run by

   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

   See if you can join NCT07209189 on ClinicalTrials.gov

6. Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)

   Patients with human papillomavirus (HPV)-related oropharyngeal cancer generally have favorable outcomes and how well they do depends on the specific details about the patient and their cancer. How well they do isn't as related to the kinds of treatment they get. However, there are significant side …

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Maryland Proton Treatment Center, Baltimore, Maryland

   Locations

   5 in total

   Run by

   University of Maryland, Baltimore

   See if you can join NCT06088381 on ClinicalTrials.gov