Gut Microbiome Clinical Trials

18 studies are recruiting for gut microbiome in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. How a Single Workout Affects Gut Bugs in Women With Different Fitness Levels and Body Types

    This study aims to elucidate the differences in the gut microbiome functional activity and metabolome in adult premenopausal women with distinctive fitness levels and BMIs (with obesity, w/o obesity). The specific aims are as follows: * Aim 1: To examine the effects of acute aerobic exercise at 60-…

    Stage
    Not phased
    Ages
    21 to 40
    Site
    Milken Institute School of Public Health, The George Washington University, Washington D.C., District of Columbia
    Run by
    George Washington University

    See if you can join NCT06691100 on ClinicalTrials.gov

  2. Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure

    The purpose of the study is to determine the effectiveness of wild blueberries on cardiovascular health, cognitive function, and gut microbiota composition in non-Hispanic Black and White adults with elevated blood pressure.

    Stage
    Not phased
    Ages
    45 to 65
    Site
    Georgia State University, Atlanta, Georgia
    Run by
    Georgia State University

    See if you can join NCT06735599 on ClinicalTrials.gov

  3. GBPDC: Gut-Brain in PD Consortium Master Protocol

    The purpose of this research study is to identify the role that the gut-brain axis, the group of nerves that connect the brain and gut, plays in Parkinson's disease (PD). The National Institute of Diabetes and Digestive and Kidney Diseases is sponsoring this research study. During this study, speci…

    Stage
    Not phased
    Ages
    21 to 80
    Site
    Stanford University, Stanford, California
    Locations
    7 in total
    Run by
    Duke University

    See if you can join NCT07567794 on ClinicalTrials.gov

  4. The Gut Microbiome and Serum Metabolites as a Biological Mechanism Underlying Pain in Kidney Transplantation

    Study Summary Nearly half (47%) of people with end-stage kidney disease (ESKD) whose kidney function is restored after kidney transplantation experience chronic pain compared to 19% of adults in the US general population. Pain is associated with comorbid fatigue, depression and anxiety, and withdra…

    Stage
    Not phased
    Ages
    18 and older
    Site
    UI Health, Chicago, Illinois
    Run by
    University of Illinois at Chicago

    See if you can join NCT06206486 on ClinicalTrials.gov

  5. The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study

    This project uses a hybrid trial design to evaluate two biomedical interventions targeting the gut-brain axis. One intervention is portable Transcutaneous Vagus Nerve Stimulator, tVNS, that is hypothesized to stimulate the autonomic nervous system, resulting in decreased inflammation and improved c…

    Stage
    Not phased
    Ages
    35 to 70
    Site
    University of Miami, Coral Gables, Florida
    Run by
    University of Florida

    See if you can join NCT05090267 on ClinicalTrials.gov

  6. Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis Risk in Postmenopausal Females

    The goal of this clinical trial is to evaluate the effects of blackcurrant (BC) supplementation on changes in bone density and gut microbiome composition in postmenopausal females.

    Stage
    Phase 1
    Ages
    45 to 70
    Site
    University of Connecticut, Department of Nutritional Sciences, Storrs, Connecticut
    Run by
    University of Connecticut

    See if you can join NCT07365514 on ClinicalTrials.gov

  7. Understanding the Efficacy of Dietary Supplement on Fungal Mycobiota in Healthy Volunteers: A Pilot Study

    The purpose of this study is to explore how the dietary supplement L-Phenylalanine affects the production of the metabolite phenylpropionic acid (PPA) and changes fungal populations of the gut microbiome.

    Stage
    Phase 4
    Ages
    18 and older
    Site
    Belfer Research Building, New York, New York
    Run by
    Weill Medical College of Cornell University

    See if you can join NCT06433310 on ClinicalTrials.gov

  8. Flourish: Exploring the Early Infant Gut Microbiome

    The goal of this clinical trial is to learn whether microbiome analysis, education, and personalized recommendations can improve gut health and reduce early markers of immune-related conditions in infants aged 0-3 months delivered via Cesarean section. The study aims to determine whether these inte…

    Stage
    Not phased
    Ages
    0 to 0
    Site
    Seeding Labs INC, Austin, Texas
    Run by
    Seeding Inc

    See if you can join NCT07333482 on ClinicalTrials.gov

  9. Effects of Mango or Low-Fat Cookie Consumption on Gut Health, and Its Relationship With Mental, Sexual and Skin Health

    The objective of the proposed research is to determine the effects of fresh mango consumption on gut microbiome, and its relationship with skin health, sexual and mental health in relatively healthy adults.

    Stage
    Not phased
    Ages
    18 to 50
    Site
    San Diego State University, San Diego, California
    Run by
    San Diego State University

    See if you can join NCT06800833 on ClinicalTrials.gov

  10. Fecal Microbiota Transplant National Registry

    A national data registry of patients receiving fecal microbiota transplantation (FMT) or other gut-related-microbiota products designed to prospectively assess short and long-term safety and effectiveness

    Stage
    Not phased
    Ages
    Any age
    Site
    Stanford University, Redwood City, California
    Locations
    53 in total
    Run by
    American Gastroenterological Association

    See if you can join NCT03325855 on ClinicalTrials.gov

  11. Curcumin and Retinal Study

    To test how two weeks of curcumin supplementation would cross the blood brain barrier (BBB) and attach to amyloid beta proteins, to assess the feasibility (safety and bioavailability), and to explore the resulting abundance/composition of gut microbiota.

    Stage
    Phase 1
    Ages
    40 to 89
    Site
    Texas Tech University Health Sciences Center, Lubbock, Texas
    Run by
    Texas Tech University Health Sciences Center

    See if you can join NCT05774704 on ClinicalTrials.gov

  12. Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury

    The Investigators will recruit 35 participants with acute SCI (within 6 weeks of injury) Fasting blood collection and bowel function survey will be conducted 3 times: at baseline [within 6 weeks of injury], 6, and 12 months after SCI. Stool will be collected for gut microbiome analysis 3 times.

    Stage
    Not phased
    Ages
    18 to 85
    Site
    The University of Alabama at Birmingahm, Birmingham, Alabama
    Run by
    University of Alabama at Birmingham

    See if you can join NCT05670288 on ClinicalTrials.gov

  13. Feasibility and Potential Efficacy of Herbs and Spices for Improving Dietary Quality in College Students: A Pilot Study

    The goal of this single-arm feasibility, pilot study is to assess the feasibility, acceptability, and potential effectiveness of the Herbs and Spices Nutrition Education Program (HSNP-focusing on incorporating herbs and spices into the diet for adherence to the DGA's) for determining the scalabilit…

    Stage
    Not phased
    Ages
    18 to 39
    Site
    Department of Kinesiology and Nutrition Sciences, Las Vegas, Nevada, Las Vegas, Nevada
    Run by
    University of Nevada, Las Vegas

    See if you can join NCT07082348 on ClinicalTrials.gov

  14. Enhanced Nutritional Optimization in LVAD Trial

    The goal of this clinical trial is to assess whether a peri-operative intervention with nutritional immune modulating intervention (Ensure Surgery Immunonutrition shake) has beneficial effects on the complex interplay between gut microbiome, systemic inflammation and malnutrition that is commonly p…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Columbia University Medical Center, New York, New York
    Run by
    Columbia University

    See if you can join NCT05655910 on ClinicalTrials.gov

  15. Early Avocado Exposure on Development and the Gut Microbiome in American Hispanic Infants

    The goal of this clinical trial is to learn if daily avocado intake can improve growth and brain and gut health in infants. The main questions it aims to answer are: Does daily eating of avocados change which microbes live in the infant's gut? Does daily avocado intake improve infant motor skills a…

    Stage
    Not phased
    Ages
    0 to 0
    Site
    College of Health Solutions, Phoenix, Arizona
    Run by
    Arizona State University

    See if you can join NCT06876935 on ClinicalTrials.gov

  16. The Effect Cranberry-Based Products on the Female Microbiome

    The overall objective of this clinical trial is to compare the effects of a cranberry-based product to a placebo-control product on vaginal and GI microbiome outcomes and associated participant reported outcomes in generally healthy pre-menopausal women

    Stage
    Not phased
    Ages
    18 to 45
    Site
    Biofortis, Chicago, Illinois
    Run by
    Ocean Spray Cranberries, Inc.

    See if you can join NCT07109713 on ClinicalTrials.gov

  17. A Study to Explore the Role of Gut Flora in COVID-19 Infection

    This study seeks to determine whether the virus which causes COVID-19, SARS-CoV-2, is shed in the stools of patients who are infected.

    Stage
    Not phased
    Ages
    18 and older
    Site
    ProgenaBiome, Ventura, California
    Run by
    ProgenaBiome

    See if you can join NCT04359836 on ClinicalTrials.gov

  18. Gut Microbiome and Treatment for Gynecological Cancer Patients Receiving Immunotherapy

    30 participants with advanced or recurrent gynecological cancer from are enrolled for this study. Eligible participants then provide fecal specimen, blood, vaginal swab, oral mucosal swab and receive food dietary recommendation. Additional samples are collected for results analysis.

    Stage
    Not phased
    Ages
    18 and older
    Site
    AdventHealth Cancer Institute, Orlando, Florida
    Run by
    Viome

    See if you can join NCT04957511 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.