Exercise Clinical Trials

21 studies are recruiting for exercise in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. How a Single Workout Affects Gut Bugs in Women With Different Fitness Levels and Body Types

   This study aims to elucidate the differences in the gut microbiome functional activity and metabolome in adult premenopausal women with distinctive fitness levels and BMIs (with obesity, w/o obesity). The specific aims are as follows: * Aim 1: To examine the effects of acute aerobic exercise at 60-…

   Stage

   Not phased

   Ages

   21 to 40

   Site

   Milken Institute School of Public Health, The George Washington University, Washington D.C., District of Columbia

   Run by

   George Washington University

   See if you can join NCT06691100 on ClinicalTrials.gov

2. Response to Exercise and Nitric Oxide in PAD

   RESIST PAD is a randomized trial of 200 PAD patients to establish: 1) whether a 12-week exercise intervention significantly increases Δ nitrite at 12-week follow-up, compared to control; 2) whether exercise "responders" have greater Δ nitrite increases compared to "non-responders"; 3) among non-res…

   Stage

   Phase 2

   Ages

   50 and older

   Site

   Northwestern University Feinberg School of Medicine, Chicago, Illinois

   Locations

   2 in total

   Run by

   Northwestern University

   See if you can join NCT06657976 on ClinicalTrials.gov

3. Goal Setting to Promote Physical Activity Adherence in Midlife Adults

   Engaging in regular physical activity during midlife is a key lifestyle behavior associated with reduced risk for Alzheimer's disease and related dementias (AD/ADRD). Yet nearly half of midlife adults (48%) do not meet national physical activity guidelines. The purpose of this mechanistic trial is …

   Stage

   Not phased

   Ages

   45 to 65

   Site

   Arizona State University, Phoenix, Arizona

   Run by

   Arizona State University

   See if you can join NCT05980052 on ClinicalTrials.gov

4. Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women

   The purpose of this study is to test a culturally tailored, smartphone-delivered intervention designed to increase physical activity and reduce risk for heart disease and type 2 diabetes among African American women.

   Stage

   Phase 2

   Ages

   24 to 65

   Site

   Arizona State University, Phoenix, Arizona

   Run by

   Arizona State University

   See if you can join NCT06337708 on ClinicalTrials.gov

5. Better Lifestyle Counseling for African American Women During Pregnancy

   The purpose of this randomized controlled trial is to establish the effectiveness of a culturally targeted and individually tailored behavioral intervention to promote maternal glucose metabolism in African American women.

   Stage

   Not phased

   Ages

   18 to 40

   Site

   University of Illinois at Chicago, Chicago, Illinois

   Locations

   2 in total

   Run by

   University of Illinois at Chicago

   See if you can join NCT05234125 on ClinicalTrials.gov

6. Developing a Nutritional Supplement to Increase Collagen Synthesis in People

   The purpose of this study is to test whether a natural product supplement can potentiate the increase in collagen synthesis following the ingestion of collagen protein. The investigators have developed a model of natural (GRAS certified) products that stimulate collagen synthesis, in vitro. The inv…

   Stage

   Not phased

   Ages

   18 to 30

   Site

   Hickey Laboratory, Davis, California

   Run by

   University of California, Davis

   See if you can join NCT06138106 on ClinicalTrials.gov

7. Physical and Cognitive Aging Study in Older Adults

   Hispanic Americans are the fastest growing older adult group in the United States, disproportionally increasing the risk of an Alzheimer's disease and related dementias diagnosis. Efforts to reduce this risk and mitigate the related cognitive/physical declines are critical. The aim of this study is…

   Stage

   Not phased

   Ages

   55 to 85

   Site

   University of Florida, College of Medicine-Jacksonville, Jacksonville, Florida

   Run by

   University of Florida

   See if you can join NCT06726616 on ClinicalTrials.gov

8. Vasodilator and Exercise Study for DMD (VASO-REx)

   Examining two strategies as potential adjuvant therapies for Duchenne muscular dystrophy (DMD); aerobic exercise training (to induce adaptations in skeletal muscle and improve cardiovascular health) and tadalafil, an FDA-approved vasodilator (to optimize blood flow and muscle perfusion which is imp…

   Stage

   Phase 2

   Ages

   6 and older

   Site

   University of Florida Clinical and Translational Research Building, Gainesville, Florida

   Run by

   University of Florida

   See if you can join NCT06290713 on ClinicalTrials.gov

9. Sex Differences in Cold-Induced Changes in Maximal Fat Oxidation

   The purpose of this research study is to determine if the cold-induced change in fat burning during exercise is different between females and males.

   Stage

   Not phased

   Ages

   18 to 40

   Site

   Colorado State University, Fort Collins, Colorado

   Run by

   Colorado State University

   See if you can join NCT07297823 on ClinicalTrials.gov

10. Phenotyping Resting and Exertional Right Ventricular Dysfunction Among Patients With Chronic Obstructive Pulmonary Disease

    This study plans to learn about heart function among individuals with chronic obstructive pulmonary disease (COPD). In particular, the investigators want to understand the different patterns of right ventricular response during rest and moderate- vs high-intensity exercise. By identifying patterns …

    Stage

    Not phased

    Ages

    40 and older

    Site

    University of Colorado Anschutz Medical Campus, Aurora, Colorado

    Run by

    University of Colorado, Denver

    See if you can join NCT05896579 on ClinicalTrials.gov

11. Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease

    This study plans to learn more about heart function among individuals with chronic obstructive pulmonary disease (COPD). In particular, the investigators want to understand the different patterns of right ventricular response during rest and moderate- vs high-intensity exercise. By identifying patt…

    Stage

    Not phased

    Ages

    40 and older

    Site

    University of Colorado Anschutz Medical Campus, Aurora, Colorado

    Run by

    University of Colorado, Denver

    See if you can join NCT07576894 on ClinicalTrials.gov

12. GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study

    Natriuretic Peptides (NP) are hormones produced by the heart, and they have a wide range of favorable metabolic benefits. Lower levels of these hormones are associated with an increased likelihood of the development of diabetes and poor cardiometabolic health. Obese and Black individuals have ~30% …

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT05216042 on ClinicalTrials.gov

13. Fasted vs. Fed State Exercise

    Although many medications exist for both heart disease and obesity, cost, lack of access for all people, side effects and the desire for a more natural solution have left many people seeking lifestyle treatments such as exercise. Scientists know that exercise is highly beneficial for heart health. …

    Stage

    Phase 2

    Ages

    18 to 59

    Site

    Arkansas Colleges of Health Education Research Institure Health and Wellness Center, Fort Smith, Arkansas

    Run by

    Arkansas Colleges of Health Education

    See if you can join NCT07487090 on ClinicalTrials.gov

14. Postnatal Exercise to Activate Baby's Brown Fat

    The purpose of this study is to learn how exercise and physical activity during pregnancy and after pregnancy may affect the composition of breastmilk. Certain changes in breast milk after exercise may have an impact on how infants use energy. Understanding this process may improve public health re…

    Stage

    Not phased

    Ages

    18 to 45

    Site

    Joslin Diabetes Center, Boston, Massachusetts

    Locations

    2 in total

    Run by

    Joslin Diabetes Center

    See if you can join NCT07467694 on ClinicalTrials.gov

15. Latinas Integrating Fitness and Therapy

    Investigators are studying how combining a stepped-care mental health counseling program with an evidence-based exercise program can help Latina cancer survivors feel better mentally and physically. The goal is to improve stress, emotions, and physical activity during and after cancer treatment. In…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Colorado State Univerisity, Fort Collins, Colorado

    Run by

    Colorado State University

    See if you can join NCT07223346 on ClinicalTrials.gov

16. The Role of Mobile Apps in Promoting Cardiovascular Health and Motivation to Exercise During Pregnancy

    The goal of this study is to determine the effectiveness of a mobile exercise app in improving cardiovascular health and motivation to exercise in pregnant women who are healthy, in their 2nd trimester, between 18-45 years age, and do not do exercise currently. The aims of this study are determine …

    Stage

    Not phased

    Ages

    18 to 45

    Site

    Old Dominion University, Norfolk, Virginia

    Run by

    Old Dominion University

    See if you can join NCT07166822 on ClinicalTrials.gov

17. Apple Health Study

    The Apple Health Study aims to build a diverse and inclusive group of participants to help researchers advance our understanding of how signals and information collected from apps and devices relate to health and may be used to predict, detect, monitor, and manage changes in health. To enroll, US r…

    Stage

    Not phased

    Ages

    18 and older

    Site

    MCRA, Washington D.C., District of Columbia

    Locations

    2 in total

    Run by

    Apple Inc.

    See if you can join NCT06958523 on ClinicalTrials.gov

18. The VESPA Pilot Study

    Physical activity has been described by the US federal government as a 'best buy' for public health. Unfortunately, most adults in the United States are not sufficiently active, and this worsens with age. Low levels of participation are driven by many challenging barriers, including lack of access,…

    Stage

    Not phased

    Ages

    45 to 80

    Site

    Wake Forest University, Winston-Salem, North Carolina

    Run by

    Wake Forest University

    See if you can join NCT04756245 on ClinicalTrials.gov

19. Ketone Monoester Supplements, High Altitude, and Brain Blood Flow During Exercise

    The purpose of this trial is to investigate the effect of acute ketone monoester ingestion (0.6 g KME/kg body weight) on the occurrence of the ventilatory threshold and the subsequent response of blood velocity in cerebral arteries during a maximal exercise test at low altitude and high altitude.

    Stage

    Not phased

    Ages

    18 to 35

    Site

    Barcroft Research Station, Bishop, California

    Locations

    2 in total

    Run by

    McMaster University

    See if you can join NCT07063732 on ClinicalTrials.gov

20. Effect of Exercise and Heat Stress on Acute Cardiometabolic Adaptations in Healthy Young Adults

    Life in space is completely void of physical and environmental stress. It is well known that living things need regular physical stress (e.g. exercise) to remain strong, functional and healthy. More and more research is showing that regular environmental stress, for example heat and hypoxia, can fu…

    Stage

    Not phased

    Ages

    18 to 50

    Site

    Northern Arizona University, Flagstaff, Arizona

    Run by

    Northern Arizona University

    See if you can join NCT06872762 on ClinicalTrials.gov

21. The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active Adults

    The purpose of this study is to determine if an acute bout of removal of exercise reduces enothelial function and glycemic control in an active, older adult population; and whether a 3 day return to exercise restores this response. Glycemic control is the blood glucose response following the consum…

    Stage

    Not phased

    Ages

    Any age

    Site

    Old Dominion University, Norfolk, Virginia

    Run by

    Old Dominion University

    See if you can join NCT05468255 on ClinicalTrials.gov