Ewing Sarcoma Clinical Trials in Dallas, Texas

4 studies are recruiting for ewing sarcoma in Dallas, Texas right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors

   This is a Phase 1 study of the combination of two drugs: MM-398 and Cyclophosphamide. The goal is to find the highest dose of MM-398 that can be given safely when it is used together with the chemotherapy drug Cyclophosphamide.

   Stage

   Phase 1

   Ages

   1 to 20

   Site

   UT Southwestern, Dallas, Texas

   Locations

   5 in total

   Run by

   South Plains Oncology Consortium

   See if you can join NCT02013336 on ClinicalTrials.gov

2. Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

   The purpose of this study is to evaluate the investigational drug, silmitasertib (a pill taken by mouth), in combination with FDA approved drugs for solid tumors. An investigational drug is one that has not been approved by the U.S. Food \& Drug Administration (FDA), or any other regulatory authori…

   Stage

   Phase 1

   Ages

   Up to 30

   Site

   Children's Medical Center, Dallas, Texas

   Locations

   24 in total

   Run by

   Milton S. Hershey Medical Center

   See if you can join NCT06541262 on ClinicalTrials.gov

3. Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

   The purpose of this study is to evaluate the investigational oral drug AMXT 1501 in combination with oral eflornithine (DFMO). An investigational drug is one that has not been approved by the U.S. Food \& Drug Administration (FDA), or any other regulatory authorities around the world for use alone …

   Stage

   Phase 1

   Ages

   Up to 26

   Site

   Children's Medical Center, Dallas, Texas

   Locations

   14 in total

   Run by

   Milton S. Hershey Medical Center

   See if you can join NCT06465199 on ClinicalTrials.gov

4. Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

   This study is conducted in two phases. The phase 1 portion of the study evaluates the safety, tolerability, pharmacokinetics (PK), recommended phase 2 dose (RP2D), and effectiveness of lurbinectedin monotherapy in pediatric participants with previously treated solid tumors. This is followed by the …

   Stage

   Phase 1

   Ages

   2 to 30

   Site

   Children's Health Dallas, Dallas, Texas

   Locations

   15 in total

   Run by

   Jazz Pharmaceuticals

   See if you can join NCT05734066 on ClinicalTrials.gov