Esophageal Adenocarcinoma Clinical Trials in Durham, North Carolina

3 studies are recruiting for esophageal adenocarcinoma in Durham, North Carolina right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

  1. Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal Adenocarcinoma

    The goal of this trial is to learn if adding consolidative chemotherapy to routine chemoradiation can better control both local recurrence and metastasis and reduce the need for surgical intervention.

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Duke University Medical Center, Durham, North Carolina
    Run by
    Duke University

    See if you can join NCT07603375 on ClinicalTrials.gov

  2. First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

    A multicenter, single-arm, first-in-human study to investigate the safety, pharmacokinetics, and preliminary antitumor activity of PLX-61639 in participants with locally advanced or metastatic, relapsed/refractory, SMARCA4-deficient solid tumors who are intolerant of or have failed available, appro…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Research Site, Durham, North Carolina
    Locations
    10 in total
    Run by
    Plexium, Inc.

    See if you can join NCT07284186 on ClinicalTrials.gov

  3. A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer

    Esophageal cancer, which has a low 5-year overall survival rate (<20%) is increasing in incidence. Previous studies have shown that Hedgehog, AKT, and angiogenic signaling pathways are activated in a significant number of esophageal cancers. Itraconazole, a widely used anti-fungal medication, effec…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Durham VA Medical Center, Durham, NC, Durham, North Carolina
    Locations
    7 in total
    Run by
    VA Office of Research and Development

    See if you can join NCT05563766 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.