Dysphagia Clinical Trials

22 studies are recruiting for dysphagia in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Boston, Massachusetts 3

Studies now recruiting

  1. The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States

    Background: Eosinophilic esophagitis (EoE) is a disease that causes inflammation in the esophagus. The esophagus is the tube that moves food from the mouth to the stomach. Diagnosing EoE currently requires a specialized tool called an endoscope. The esophageal string test (EST) is another test; the…

    Stage
    Not phased
    Ages
    18 to 65
    Site
    National Institutes of Health Clinical Center, Bethesda, Maryland
    Locations
    3 in total
    Run by
    National Institute of Allergy and Infectious Diseases (NIAID)

    See if you can join NCT07027826 on ClinicalTrials.gov

  2. Respiratory Strength Training in Heart Transplant Recipients

    This research study is investigating whether completing breathing exercises before surgery helps heart transplant patients recover after surgery. Previous studies have shown that breathing exercises can improve breathing, cough, and swallow function in patients with other diseases/conditions. The c…

    Stage
    Not phased
    Ages
    18 to 90
    Site
    Vanderbilt University Medical Center, Nashville, Tennessee
    Run by
    Vanderbilt University Medical Center

    See if you can join NCT06190171 on ClinicalTrials.gov

  3. Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease

    Dysphagia, or difficulty swallowing, is a common symptom of many neurological diseases but its treatment is not well established or easily accessible. To start addressing this gap, the researchers developed and validated a cost-effective wearable surface electromyography (sEMG) biofeedback sensor t…

    Stage
    Phase 2
    Ages
    50 to 90
    Site
    University of Illinois Urbana-Champaign, Champaign, Illinois
    Locations
    2 in total
    Run by
    University of Illinois at Urbana-Champaign

    See if you can join NCT06638944 on ClinicalTrials.gov

  4. K01 Impacts of Lingual Endurance Exercise

    The goal of this clinical trial is to learn whether a tongue endurance exercise program can improve swallowing function in adults with dysphagia after a stroke. It also aims to explore how this exercise may affect brain structure and connectivity involved in swallowing. The main questions it aims t…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Cincinnati, Cincinnati, Ohio
    Run by
    University of Cincinnati

    See if you can join NCT06072924 on ClinicalTrials.gov

  5. A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's

    The purpose of this study is the development and early-stage validation of a wearable sensor for dysphagia in patients with PD.

    Stage
    Phase 3
    Ages
    22 and older
    Site
    Northwestern University, Evanston, Illinois
    Run by
    Northwestern University

    See if you can join NCT04664634 on ClinicalTrials.gov

  6. Impact of Body Positioning on EndoFLIP Measurements: A Comparative Study of Supine and Left Lateral Decubitus Positions

    This is a prospective, single-center, crossover study comparing EndoFLIP measurements obtained in two patient positions, supine and left lateral decubitus, in pediatric and young adult patients. The Endoluminal Functional Lumen Imaging Probe (EndoFLIP) is an FDA-approved device for patients aged 5 …

    Stage
    Not phased
    Ages
    5 to 21
    Site
    Charlotte R. Bloomberg Children's Center, Baltimore, Maryland
    Run by
    Johns Hopkins University

    See if you can join NCT07780981 on ClinicalTrials.gov

  7. Phagenyx® Registry Study

    A retrospective, open-label, matched-control registry study designed to characterize the effectiveness of Pharyngeal Electrical Stimulation (PES) to improve swallowing in patients with severe dysphagia post stroke when delivered using the Phagenyx® System in real-world clinical settings in hospital…

    Stage
    Not phased
    Ages
    Any age
    Site
    Banner University Medical Center, Phoenix, Arizona
    Locations
    3 in total
    Run by
    Phagenesis Ltd.

    See if you can join NCT06866418 on ClinicalTrials.gov

  8. Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic Treatment

    The objective of the study is to investigate the treatment of marginal ulcers with Low Thermal plasma in an endoscopic setting. By a treatment of the ulcerated areas with argon plasma with low power settings (~ 1 W) we hypothesize that the size of the ulcers will shrink, and the healing is accelera…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Brigham and Women's Hospital, Boston, Massachusetts
    Run by
    Christopher C. Thompson, MD, MSc

    See if you can join NCT06543316 on ClinicalTrials.gov

  9. Swallowing Impairments in Adults With and Without Alzheimer's Disease

    This research study is investigating whether people with Alzheimer's disease (AD) experience more changes to swallowing than their healthy age-matched peers. The prevalence of swallowing impairments in moderate-severe AD is high (85-93%), yet little is known about how swallow function evolves throu…

    Stage
    Not phased
    Ages
    60 and older
    Site
    Vanderbilt University Medical Center, Nashville, Tennessee
    Run by
    Vanderbilt University Medical Center

    See if you can join NCT06678100 on ClinicalTrials.gov

  10. Corticosteroids for Post-Extubation Dysphagia

    This is a placebo-controlled, double-blind randomized trial of a short course of intravenous corticosteroids for Acute Respiratory Failure Survivors with Fiberoptic Endoscopic Evaluation of Swallowing (FEES) documented laryngeal edema. Study was leveraged using the existing R01 grant infrastructure…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    University of Colorado, Aurora, Colorado
    Run by
    University of Colorado, Denver

    See if you can join NCT06670521 on ClinicalTrials.gov

  11. Non-standardized vs. Standardized Screening for Dysphagia

    The purpose of this study is to compare two different screening tests for detecting dysphagia (difficulty swallowing) as well as the risk for aspiration (silent swallowing of liquids/solids into the lungs) in patients after an ischemic stroke (when a blood clot blocks or narrows an artery leading t…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Lynn Rehabilitation Center / University of Miami, Miami, Florida
    Run by
    University of Miami

    See if you can join NCT05603897 on ClinicalTrials.gov

  12. Velopharyngeal Dysfunction in Head & Neck Cancer Patients, Pilot Study

    Some head and neck cancer survivors develop velopharyngeal dysfunction (VPD), a problem with closure between the soft palate and throat that can cause nasal-sounding speech, food or liquid leaking into the nose, difficulty swallowing, and reduced quality of life. This study aims to better understan…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Virginia, Charlottesville, Virginia
    Run by
    Vanessa Torrecillas

    See if you can join NCT07264036 on ClinicalTrials.gov

  13. Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia

    This study will examine the effects of varying liquid viscosity on swallow physiology in infants with oropharyngeal dysphagia and brief resolved unexplained event (BRUE) and other children with dysphagia that would be at risk for symptoms of swallow dysfunction.

    Stage
    Not phased
    Ages
    Up to 21
    Site
    Boston Children's Hospital, Boston, Massachusetts
    Run by
    Boston Children's Hospital

    See if you can join NCT04504227 on ClinicalTrials.gov

  14. Anterior Cervical Discectomy and Fusion (ACDF) - Behavioral Intervention

    This study will prospectively recruit and enroll patients undergoing primary Anterior Cervical Discectomy and Fusion (ACDF) surgeries at NYU Langone. Participants will undergo pre-operative and six-week post-operative swallowing assessment using videofluoroscopy (VFSS). Acoustic voice samples and P…

    Stage
    Not phased
    Ages
    21 to 99
    Site
    NYU Langone Health, New York, New York
    Run by
    NYU Langone Health

    See if you can join NCT06520579 on ClinicalTrials.gov

  15. External Pharyngeal Exerciser and Dysphagia

    The goal of this a clinical trial is to test the effect of a pharyngeal exerciser in rehabilitation of pharyngeal phase of swallowing in patients with dysphagia. The main question it aims to answer is: •Does application of pharyngeal exerciser improve swallowing as evidenced by need for prescribed …

    Stage
    Not phased
    Ages
    18 and older
    Site
    Medical College of Wisconsin, Milwaukee, Wisconsin
    Run by
    Medical College of Wisconsin

    See if you can join NCT05708898 on ClinicalTrials.gov

  16. Dissemination and Implementation of DIGEST™ as an Evidence-based Measurement Tool for Dysphagia: A Randomized Implementation Trial

    To improve swallowing outcomes in cancer through clinical implementation of the Dynamic Imaging Grade of Swallowing Toxicity (DIGEST™) as an evidence-based practice (EBP) tool to grade pharyngeal dysphagia (difficulty swallowing) as a toxicity of cancer.

    Stage
    Not phased
    Ages
    18 and older
    Site
    MD Anderson Cancer Center, Houston, Texas
    Run by
    M.D. Anderson Cancer Center

    See if you can join NCT07283653 on ClinicalTrials.gov

  17. External Pharyngeal Exerciser and Pharyngeal Phase of Swallowing

    This study of healthy young and elderly individuals is intended to assess the effects of pharyngeal exerciser on pharyngeal pressure phenomenon during swallowing. Our specific aim is to test if the pharyngeal exerciser increases the workload of muscles involved in pharyngeal phase of swallowing.

    Stage
    Not phased
    Ages
    18 to 85
    Site
    Medical College of Wisconsin, Milwaukee, Wisconsin
    Run by
    Medical College of Wisconsin

    See if you can join NCT05708911 on ClinicalTrials.gov

  18. Combined Respiratory Training in Persons With ALS

    The goal of this interventional trial is to learn about lung volume recruitment (LVR) and expiratory muscle strength training (EMST) in a total of up to 39 patients diagnosed with ALS. The following aims will be addressed: 1. Determine the impact of combined LVR and EMST on cough strength and respi…

    Stage
    Not phased
    Ages
    18 to 90
    Site
    Nova Southeastern University, Fort Lauderdale, Florida
    Run by
    Nova Southeastern University

    See if you can join NCT05913882 on ClinicalTrials.gov

  19. Dysphagia Study Using Novel Microphone Device

    This study aims to collect swallowing acoustics with a novel non-invasive wearable surface microphone device during routine work-up, videofluoroscopic swallow study (VFSS), of patients with dysphagia (swallowing trouble). The collected microphone data will be analyzed to find the pattern of abnorma…

    Stage
    Not phased
    Ages
    40 to 85
    Site
    Emory University Hospital Midtown, Atlanta, Georgia
    Locations
    2 in total
    Run by
    Emory University

    See if you can join NCT07251140 on ClinicalTrials.gov

  20. Rehabilitation of Airway Protection in Parkinson's Disease

    Airway protective disorders are a prevalent and progressive consequence of Parkinson's Disease (PD), and often result in aspiration pneumonia which is the leading cause of death in PD. Despite this, a large number of patients with PD do not access specialized services to address these critical defi…

    Stage
    Phase 2
    Ages
    50 to 90
    Site
    Purdue University, West Lafayette, Indiana
    Locations
    2 in total
    Run by
    Teachers College, Columbia University

    See if you can join NCT05700825 on ClinicalTrials.gov

  21. Evolution of the Chicago Classification: Bridging Physiology and Mechanics

    Swallowing difficulties are extremely common and result in substantial morbidity, reduction in the quality of life, and mortality related to malnutrition and complications from regurgitation and aspiration. Unfortunately, our understanding regarding the pathophysiology of dysphagia and GERD has bee…

    Stage
    Not phased
    Ages
    18 to 85
    Site
    Northwestern University, Chicago, Illinois
    Run by
    Northwestern University

    See if you can join NCT06883175 on ClinicalTrials.gov

  22. Aspiration in Acute Respiratory Failure Survivors 2

    The purpose of this study is to learn more about problems with swallowing that could develop in patients who are very sick and need a machine to help them breathe.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Stanford Univerity, Stanford, California
    Locations
    5 in total
    Run by
    University of Colorado, Denver

    See if you can join NCT05108896 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.