Diffuse Intrinsic Pontine Glioma Clinical Trials in Miami, Florida

5 studies are recruiting for diffuse intrinsic pontine glioma in Miami, Florida right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Targeted Pediatric High-Grade Glioma Therapy

   The goal of this study is to perform genetic sequencing on brain tumors from children, adolescents, and young adult patients who have been newly diagnosed with a high-grade glioma. This molecular profiling will decide if patients are eligible to participate in a subsequent treatment-based clinical …

   Stage

   Not phased

   Ages

   1 to 39

   Site

   University of Miami, Miami, Florida

   Locations

   22 in total

   Run by

   Nationwide Children's Hospital

   See if you can join NCT05839379 on ClinicalTrials.gov

2. Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

   The purpose of this study is to evaluate the investigational oral drug AMXT 1501 in combination with oral eflornithine (DFMO). An investigational drug is one that has not been approved by the U.S. Food \& Drug Administration (FDA), or any other regulatory authorities around the world for use alone …

   Stage

   Phase 1

   Ages

   Up to 26

   Site

   Nicklaus Children's Hospital, Miami, Florida

   Locations

   14 in total

   Run by

   Milton S. Hershey Medical Center

   See if you can join NCT06465199 on ClinicalTrials.gov

3. Study of Olutasidenib and Temozolomide in HGG

   The goal of this study is to determine the efficacy of the study drug olutasidenib to treat newly diagnosed pediatric and young adult patients with a high-grade glioma (HGG) harboring an IDH1 mutation. The main question the study aims to answer is whether the combination of olutasidenib and temozol…

   Stage

   Phase 2

   Ages

   12 to 39

   Site

   University of Miami Hospital and Clinics, Miami, Florida

   Locations

   20 in total

   Run by

   Rigel Pharmaceuticals

   See if you can join NCT06161974 on ClinicalTrials.gov

4. PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

   This study will address the question of whether targeting CMV antigens with PEP-CMV can serve as a novel immunotherapeutic approach in pediatric patients with newly-diagnosed high-grade glioma (HGG) or diffuse intrinsic pontine glioma (DIPG) as well as recurrent medulloblastoma (MB). PEP-CMV is a v…

   Stage

   Phase 2

   Ages

   3 to 39

   Site

   Nicklaus Children's Hospital, Miami, Florida

   Locations

   13 in total

   Run by

   Nationwide Children's Hospital

   See if you can join NCT05096481 on ClinicalTrials.gov

5. Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age

   This study assesses the safety and efficacy of repeat monthly dosing of super-selective intra-arterial cerebral infusion (SIACI) of cetuximab and bevacizumab in patients < 22 years of age.

   Stage

   Phase 1

   Ages

   1 to 21

   Site

   Jackson Memorial Hospital, Miami, Florida

   Run by

   University of Miami

   See if you can join NCT05956821 on ClinicalTrials.gov