Diabetes Clinical Trials

81 studies are recruiting for diabetes in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Care Transitions App for Patients With Multiple Chronic Conditions

   The objective of this study is to widely implement and evaluate the Care Transitions App in a randomized controlled trial. The app the investigators designed for patients with multiple chronic conditions has four envisioned modules: 1) falls-reduction content, 2) a digital post-discharge transition…

   Stage

   Not phased

   Ages

   55 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT06051058 on ClinicalTrials.gov

2. Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

   Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease globally. While weight loss through lifestyle modification is the standard treatment, most patients regain weight limiting ultimate improvement in liver disease. On the other end of the spectru…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Pichamol Jirapinyo, MD, MPH

   See if you can join NCT06138821 on ClinicalTrials.gov

3. Circulating Biomarkers in the Development of Type 1 Diabetes

   More than 100 million U.S. adults are now living with diabetes or prediabetes. Investigators still do not fully understand how diabetes develops and how the disease worsens. Insulin is a hormone that helps the body use sugar as a fuel and control blood-sugar levels. People with diabetes have proble…

   Stage

   Not phased

   Ages

   Any age

   Site

   City of Hope Medical Center, Duarte, California

   Run by

   City of Hope Medical Center

   See if you can join NCT05505669 on ClinicalTrials.gov

4. Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery

   The goal of this randomized controlled trial is to compare the efficacy and safety of the iLet Bionic Pancreas (BP) System in adults with insulin-treated diabetes (type 1 diabetes or type 2 diabetes) compared to standard of care when ordered by primary care providers. The main question it aims to a…

   Stage

   Not phased

   Ages

   18 to 89

   Site

   University of Colorado Anschutz Medical Campus, Aurora, Colorado

   Locations

   2 in total

   Run by

   University of Colorado, Denver

   See if you can join NCT07011147 on ClinicalTrials.gov

5. Sisters for Heart Health: A Community Health Worker Initiative for Improving Heart Health in Farmworker Women

   The goal of this hybrid Type 1 effectiveness-implementation trial is to test the extent to which a peer support and community resource navigation intervention improves psychological well-being, addresses non-biologic drivers of health (access to healthcare, supportive services, nutrition, housing s…

   Stage

   Not phased

   Ages

   18 to 50

   Site

   Southern GA - Colquitt County, Ellenton, Georgia

   Run by

   Emory University

   See if you can join NCT07111026 on ClinicalTrials.gov

6. Social Needs Screening and Chronic Diseases Study (WE CARE)

   The goal of this clinical trial is to learn if the implementation of the WE CARE social determinants of health (SDOH) screening and referral intervention with an antiracist lens in primary care settings can lead to a meaningful decrease in chronic disease by monitoring conditions such as hypertensi…

   Stage

   Not phased

   Ages

   Any age

   Site

   UMass Memorial Medical Center - Hahnemann Campus, Worcester, Massachusetts

   Locations

   3 in total

   Run by

   University of Massachusetts, Worcester

   See if you can join NCT06903897 on ClinicalTrials.gov

7. GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

   Diabetes is a major co-morbidity in pancreatic insufficient cystic fibrosis (PI-CF) and associated with worse outcomes. While reduced β-cell mass contributes to the insulin secretory defects that characterizes cystic fibrosis-related diabetes (CFRD), other modifiable determinants appear operative i…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Children's Hospital of Colorado, Aurora, Colorado

   Locations

   2 in total

   Run by

   University of Pennsylvania

   See if you can join NCT04731272 on ClinicalTrials.gov

8. Diabetes Clinical Decision Support

   The purpose of this study is to determine the impact of an electronic medical record clinical decision support tool on rates of dysglycemia in the hospital, and its clinical and economical outcomes. The study also evaluates the perspectives of providers regarding the tool's usefulness on disease ma…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Penn State Hershey Medical Center, Hershey, Pennsylvania

   Locations

   2 in total

   Run by

   Milton S. Hershey Medical Center

   See if you can join NCT05447806 on ClinicalTrials.gov

9. Monitoring Exhaled Breath to Noninvasively Detect Glycemic Events

   The purpose of this study is to determine whether an array of biosensors can noninvasively identify hyperglycemic or hypoglycemic events in persons diagnosed with diabetes through noninvasive detection of volatile organic compounds in exhaled breath.

   Stage

   Not phased

   Ages

   12 to 19

   Site

   Indiana University, Indianapolis, Indiana

   Run by

   Indiana University

   See if you can join NCT06893341 on ClinicalTrials.gov

10. Extended Oral Antibiotic Prophylaxis in Diabetic Fracture Patients

    The goal of this clinical trial is to learn if taking an antibiotic pill for 7 days after surgery reduces the risk of wound infection in adults with poorly controlled diabetes who have surgery to fix a broken bone in the leg, ankle, or foot. It will also learn about the safety of the extended antib…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    University of Southern California, Los Angeles, California

    Locations

    3 in total

    Run by

    Texas Tech University Health Sciences Center, El Paso

    See if you can join NCT07561541 on ClinicalTrials.gov

11. Using Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes

    A pragmatic electronic health record (EHR) based randomized controlled trial to evaluate the utility of providing Ultromics EchoGo analysis results and recommendations for HF risk prevention therapies using an EHR embedded clinical decision support tool.

    Stage

    Not phased

    Ages

    Any age

    Site

    UT Southwestern Medical Center, Dallas, Texas

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT06593314 on ClinicalTrials.gov

12. Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

    The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research on chronic diseases, nutrition, and metabolism (the process by which a…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    University of Missouri-Columbia, Columbia, Missouri

    Run by

    Bettina Mittendorfer

    See if you can join NCT07083557 on ClinicalTrials.gov

13. Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

    Skeletal muscle metabolic health is critical for mobility and an underrecognized target of metabolic acidosis in chronic kidney disease. Impaired muscle mitochondrial metabolism underlies poor physical endurance increasing the risk of mobility disability. The proposed project will use precise in vi…

    Stage

    Phase 2

    Ages

    21 to 85

    Site

    University of California Davis Health, Sacramento, California

    Locations

    2 in total

    Run by

    University of California, Davis

    See if you can join NCT04984226 on ClinicalTrials.gov

14. Continuous Glucose Monitoring (CGM) in an Underserved Population

    The investigators aim is to conduct a randomized clinical trial in an underserved population who are either uninsured or on Medicaid and taking at least one injection of insulin daily. The investigators believe that this study will lead to considerable alleviation of health disparities and provide …

    Stage

    Not phased

    Ages

    18 to 75

    Site

    University Medical Center, New Orleans, Louisiana

    Run by

    Tulane University

    See if you can join NCT07135531 on ClinicalTrials.gov

15. Supporting VETerans With Kidney Disease Through Food As Medicine

    The goal of this pilot clinical trial is primarily learn if produce boxes improve clinical outcomes among Veterans with kidney disease and food or nutrition insecurity. Secondly, the study will capture Veterans qualitative perspectives, experience, and engagement through semi-structured interviews.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Rocky Mountain Regional VA Medical Center, Aurora, Colorado

    Run by

    VA Eastern Colorado Health Care System

    See if you can join NCT07194733 on ClinicalTrials.gov

16. ROME GS System Study

    The purpose of this clinical investigation is to demonstrate that the proposed physical changes to the ROME GS Sensor do not have any adverse impact on safety and performance when compared to the Eversense 365 Sensor.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Headlands Research - AMCR Institute, Escondido, California

    Locations

    4 in total

    Run by

    Senseonics, Inc.

    See if you can join NCT07518004 on ClinicalTrials.gov

17. Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide

    This study is to investigate how adipocyte (fat cell) function and fat distribution differ between individuals with normal-weight type 2 diabetes (NWD), those with overweight type 2 diabetes (OWD), and normal-weight controls without diabetes (NWC). The study will assess whether adipocyte-directed t…

    Stage

    Phase 4

    Ages

    30 to 70

    Site

    Stanford University, Palo Alto, California

    Locations

    2 in total

    Run by

    Stanford University

    See if you can join NCT06657209 on ClinicalTrials.gov

18. Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial

    This is a prospective, multi-center, two-arm, randomized trial to quantify the performance of the EchoMark®/EchoSure® System for AVF diagnostic ultrasound when used under a protocol of biweekly use for assessing fistula maturation and reducing time to Clinical Maturation.

    Stage

    Not phased

    Ages

    18 to 84

    Site

    Trinity Research Group, Dothan, Alabama

    Locations

    21 in total

    Run by

    Sonavex, Inc.

    See if you can join NCT06190717 on ClinicalTrials.gov

19. Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients

    The purpose of this study is to determine which of the following four service models is most effective for reducing fall risk among home-delivered meal clients: (1) meals alone, (2) meals + registered dietitian services, (3) meals + occupational therapy services, (4) meals + registered dietitian + …

    Stage

    Not phased

    Ages

    60 and older

    Site

    LifeCare Alliance, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT06586970 on ClinicalTrials.gov

20. Leveraging Community-clinical Linkages to Address Unmet Social Needs for People With Diabetes

    This study is a hybrid type 2 design to evaluate the effectiveness and implementation of a community-clinical linkage intervention in primary clinics to address unmet social needs for patients with diabetes living in rural communities. The study will take place in two rural communities in Kentucky,…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Kentucky, Lexington, Kentucky

    Run by

    Mary Lacy

    See if you can join NCT07196007 on ClinicalTrials.gov

21. Pancreatic Islet Transplantation Into the Anterior Chamber of the Eye

    The intervention in this trial is intraocular islet transplantation. A single dose of 1000 - 3000 Islet Equivalents (IEQ)/kg recipient body weight (BW) will be infused into the anterior chamber of the eye through a self-sealing incision in the peripheral cornea. The procedure is projected to take a…

    Stage

    Phase 1

    Ages

    18 to 75

    Site

    Bascom Palmer Eye Institute, Miami, Florida

    Locations

    2 in total

    Run by

    Midhat H. Abdulreda

    See if you can join NCT02846571 on ClinicalTrials.gov

22. Remote Fetal Monitoring in High Risk Pregnancies

    Antenatal nonstress tests (NSTs) are performed to assess fetal health and are used as a cost-effective test that can be widely administered. However, an NST is operator-dependent due to the nature of Doppler ultrasound and is primarily performed in a clinic and hospital setting. The ability to cond…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Beth Israel Deaconess Medical Center, Boston, Massachusetts

    Run by

    Beth Israel Deaconess Medical Center

    See if you can join NCT06822439 on ClinicalTrials.gov

23. CHIME: Comparing Health Interventions for Maternal Equity

    The goal of this comparative effectiveness trial is to compare how three different approaches to overcome barriers to resources and provide nutrition and physical activity counseling improve maternal healthy weight in pregnancy and postpartum. The main question it aims to answer is which of the two…

    Stage

    Not phased

    Ages

    18 and older

    Site

    New York Presbyterian Queens, Flushing, New York

    Locations

    4 in total

    Run by

    Stanford University

    See if you can join NCT06724172 on ClinicalTrials.gov

24. Imaging the Pathogenesis of Cerebral Small Vessel Disease

    Cerebral small vessel disease (CSVD) can lead to vascular cognitive impairment and dementia (VCID). The hallmark of CSVD is the appearance and progression of white matter hyperintensities (WMH) on MRI. The goal of this study it to recruit and follow individuals at risk for WMH progression and use s…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Kennedy Krieger Institute, Baltimore, Maryland

    Run by

    Johns Hopkins University

    See if you can join NCT05703386 on ClinicalTrials.gov

25. Pre-Surgical Tirzepatide-Assisted Weight Loss in Overweight and Obese Men With Intermediate Risk Prostate Cancer: A Pilot Feasibility Study

    The goal of this clinical research study is to determine how well a tirzepatide-assisted weight loss program works before a prostatectomy in patients with intermediate risk prostate cancer

    Stage

    EARLY_Phase 1

    Ages

    18 and older

    Site

    The University of Texas M. D. Anderson Cancer Center, Houston, Texas

    Run by

    M.D. Anderson Cancer Center

    See if you can join NCT06759701 on ClinicalTrials.gov