Diabetes Mellitus Clinical Trials

52 studies are recruiting for diabetes mellitus in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Early Tracking of Childhood Health Determinants (ETCHED) Study

   Background: Children s weight has increased sharply in recent years. This may put them at higher risk for health problems. High blood glucose in a pregnant mother and too much weight gain during pregnancy also may have long-term effects on the child s health. Children who become overweight or obese…

   Stage

   Not phased

   Ages

   0 to 99

   Site

   NIDDK, Phoenix, Phoenix, Arizona

   Run by

   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

   See if you can join NCT03481829 on ClinicalTrials.gov

2. Impact GLP-1 Agonists Following Bariatric

   Glucagon-like peptide 1 (GLP-1) is a hormone that helps regulate blood glucose levels through improved insulin sensitivity and release of insulin from the pancreas, control hunger, induce satiety and plays a role in the metabolic health of a person. GLP-1 receptor agonists (GLP1-RAs) have been show…

   Stage

   Phase 4

   Ages

   18 and older

   Site

   University of Missouri Hospital, Columbia, Missouri

   Run by

   University of Missouri-Columbia

   See if you can join NCT06132477 on ClinicalTrials.gov

3. Inflammation, Diabetes, Ethnicity and Obesity Cohort

   Obesity affects over one third of US adults (>72 million, with BMI ≥30 kg/m2), and the proportion of US adults with BMI ≥40 kg/m2 has doubled in the last 20 years. Obesity is associated with increased mortality through its linkage to comorbidities including diabetes, hypertension, dyslipidemia, ost…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   University of California San Francisco, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT03022682 on ClinicalTrials.gov

4. AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

   The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight and type 2 diabetes. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111 (the trea…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Univ of Alabama Birmingham, Birmingham, Alabama

   Locations

   74 in total

   Run by

   Novo Nordisk A/S

   See if you can join NCT07533175 on ClinicalTrials.gov

5. Arizona CEAL: Linking Social Care With Healthcare Systems to Address SDOH

   The goal of the Arizona Community Engagement Alliance (AZ-CEAL) will be to combine social care with healthcare programs. The study will be connecting selected patients from clinics with trained community health workers (CHW) who will assist participants in getting the help that is needed for their …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Banner University Medical Center South, Tucson, Arizona

   Locations

   2 in total

   Run by

   Sairam Parthasarathy

   See if you can join NCT07799961 on ClinicalTrials.gov

6. Genetic Studies of Insulin and Diabetes

   The study will allow researchers to obtain blood, plasma, DNA, and RNA for genetic studies of insulin. There will be a focus on the causes of insulin resistance and diabetes mellitus. Insulin is a hormone found in the body that controls the level of sugar in the blood. Insulin resistance refers to …

   Stage

   Not phased

   Ages

   0 to 120

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

   See if you can join NCT00001987 on ClinicalTrials.gov

7. Impact of Removable Cast Walker Design on Usability for Patients With Diabetic Foot Ulcers

   Within their lifetime, over 30% of people living with diabetes will develop a diabetic foot ulcer (DFU), many of which will never heal and may require amputation. Removable cast walkers (RCWs) are commonly prescribed to offload (treat) DFUs. While RCWs are prescribed to be worn during all weight be…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Rosalind Franklin University of Medicine and Science, North Chicago, Illinois

   Run by

   Rosalind Franklin University of Medicine and Science

   See if you can join NCT05415878 on ClinicalTrials.gov

8. A Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors

   The investigators will conduct a feasibility and pilot efficacy randomized controlled trial to test the usability and user satisfaction of an evidence-based digital health tool the investigators developed for physicians to use to Prioritize Personalize Prescribe EXercise (P3-EX) to patients with ca…

   Stage

   Not phased

   Ages

   18 to 64

   Site

   Hartford HealthCare, Hartford, Connecticut

   Locations

   3 in total

   Run by

   University of Connecticut

   See if you can join NCT07238556 on ClinicalTrials.gov

9. Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis/Acute Pancreatitis Associated Diabetes Mellitus

   The purpose of this study is to evaluate efficacy of pioglitazone (PIO) versus empagliflozin (EMPA) to improve glycemic control in people with Chronic Pancreatitis (CP) or Recurrent Acute Pancreatitis (RAP) or Acute Pancreatitis (AP) associated with Diabetes Mellitus (DM). To evaluate mixed meal re…

   Stage

   Phase 2

   Ages

   18 to 80

   Site

   Mayo Clinic, Rochester, Minnesota

   Locations

   3 in total

   Run by

   Mayo Clinic

   See if you can join NCT06729996 on ClinicalTrials.gov

10. NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals

    Black individuals are more likely to have decreased insulin sensitivity which results in a high risk for the development of cardiometabolic disease. The reasons for this are incompletely understood. Natriuretic peptides (NPs) are hormones produced by the heart that play a role in regulating the met…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT04055428 on ClinicalTrials.gov

11. Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women

    The purpose of this study is to test a culturally tailored, smartphone-delivered intervention designed to increase physical activity and reduce risk for heart disease and type 2 diabetes among African American women.

    Stage

    Phase 2

    Ages

    24 to 65

    Site

    Arizona State University, Phoenix, Arizona

    Run by

    Arizona State University

    See if you can join NCT06337708 on ClinicalTrials.gov

12. Inpatient Use of Personal Continuous Glucose Monitor (CGM) to Improve Diabetes Mellitus Control

    The purpose of this research is to prove that data generated by your real-time personal continuous glucose monitors CGMs brought in the hospital at the time of hospitalization can be monitored and safely used to guide insulin therapy aiming to improve glycemic control and to diminish the hypoglycem…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Florida, Jacksonville, Florida

    Run by

    Mayo Clinic

    See if you can join NCT07006480 on ClinicalTrials.gov

13. Care Transitions App for Patients With Multiple Chronic Conditions

    The objective of this study is to widely implement and evaluate the Care Transitions App in a randomized controlled trial. The app the investigators designed for patients with multiple chronic conditions has four envisioned modules: 1) falls-reduction content, 2) a digital post-discharge transition…

    Stage

    Not phased

    Ages

    55 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Run by

    Brigham and Women's Hospital

    See if you can join NCT06051058 on ClinicalTrials.gov

14. SPYRAL GEMINI Pilot Study

    The purpose of the SPYRAL GEMINI Pilot Study is to evaluate that multi-organ denervation with the Gemini System is safe and provide evidence of blood pressure reduction when studied in an uncontrolled hypertensive population with and without high cardiovascular risk.

    Stage

    Not phased

    Ages

    18 to 80

    Site

    Stanford Hospital and Clinics, Stanford, California

    Locations

    18 in total

    Run by

    Medtronic Vascular

    See if you can join NCT06907147 on ClinicalTrials.gov

15. SPARK-CGM Implementation

    Continuous glucose monitoring (CGM) is a technology that helps individuals with diabetes track their sugar levels in real-time, leading to more in-range blood sugars, fewer episodes of dangerously low blood sugar, and improved quality of life. Despite these benefits, CGM is not widely used in prima…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Montefiore Medical Group (MMG), The Bronx, New York

    Run by

    Montefiore Medical Center

    See if you can join NCT07548372 on ClinicalTrials.gov

16. Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery

    The goal of this randomized controlled trial is to compare the efficacy and safety of the iLet Bionic Pancreas (BP) System in adults with insulin-treated diabetes (type 1 diabetes or type 2 diabetes) compared to standard of care when ordered by primary care providers. The main question it aims to a…

    Stage

    Not phased

    Ages

    18 to 89

    Site

    University of Colorado Anschutz Medical Campus, Aurora, Colorado

    Locations

    2 in total

    Run by

    University of Colorado, Denver

    See if you can join NCT07011147 on ClinicalTrials.gov

17. Continuous Glucose Monitor for Mayo Clinic Advanced Care at Home Patients

    The purpose of this study is to measure differences in diabetes control with the use of continuous glucose monitor (CGM) and diabetes education compared with standard of care for glucose monitoring (glucometer checks) and diabetes education in participants with diabetes mellitus receiving therapy w…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Florida, Jacksonville, Florida

    Run by

    Mayo Clinic

    See if you can join NCT05880810 on ClinicalTrials.gov

18. American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

    Despite many advances in our understanding of the natural history and progression of chronic kidney disease (CKD) and cardio vascular disease (CVD) in the parent CRIC study over the past 15 years, important questions about key risk factors for these diseases remain unanswered in the AI population. …

    Stage

    Not phased

    Ages

    21 to 80

    Site

    First Nations Community Health Source, Albuquerque, New Mexico

    Locations

    3 in total

    Run by

    University of New Mexico

    See if you can join NCT04185844 on ClinicalTrials.gov

19. ED Diabetes Screening and Outpatient Care - Aim 3

    This goal of this NIH funded R01 study is to identify risk factors for not being able to follow-up for a new diagnosis of diabetes in the emergency department and improve linkage of these newly diagnosed patients to appropriate outpatient care. Its three aims will be accomplished through 1) a retro…

    Stage

    Not phased

    Ages

    20 to 70

    Site

    NYU Langone Health, New York, New York

    Run by

    NYU Langone Health

    See if you can join NCT05899023 on ClinicalTrials.gov

20. Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults

    CHRONICLE is a randomized trial assessing the comparative effectiveness of providing written visit information via the patient portal (NOTES) versus NOTES plus visit audio recording (AUDIO) to older adult patients with chronic diseases on quality of life and other outcomes. During the trial, the te…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Dartmouth Hitchcock Clinics Manchester, Manchester, New Hampshire

    Locations

    3 in total

    Run by

    Dartmouth-Hitchcock Medical Center

    See if you can join NCT05955339 on ClinicalTrials.gov

21. Continuous Glucose Monitoring (CGM) in an Underserved Population

    The investigators aim is to conduct a randomized clinical trial in an underserved population who are either uninsured or on Medicaid and taking at least one injection of insulin daily. The investigators believe that this study will lead to considerable alleviation of health disparities and provide …

    Stage

    Not phased

    Ages

    18 to 75

    Site

    University Medical Center, New Orleans, Louisiana

    Run by

    Tulane University

    See if you can join NCT07135531 on ClinicalTrials.gov

22. Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia

    Researchers are trying to understand why people with indigestion and diabetes mellitus have gastrointestinal symptoms and in particular to understand whether symptoms are related to increased sensitivity to nutrients in the small intestine. As part of this investigation, a medication called ondanse…

    Stage

    Phase 2

    Ages

    18 to 75

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT03865290 on ClinicalTrials.gov

23. Regulation of Endogenous Glucose Production by Central KATP Channels

    Type 2 diabetes (T2D) affects the ability of the body to process glucose (sugar). Under fasting conditions, the liver is able to make sugar to maintain glucose levels in an important process called endogenous glucose production (EGP). Previous studies suggest that the central nervous system (CNS), …

    Stage

    Phase 2

    Ages

    21 to 70

    Site

    Albert Einstein College of Medicine, The Bronx, New York

    Run by

    Albert Einstein College of Medicine

    See if you can join NCT03540758 on ClinicalTrials.gov

24. Sleep, Diabetic Retinopathy and Melatonin

    This study explores the use of melatonin in patients with diabetic retinopathy

    Stage

    Phase 2

    Ages

    40 to 65

    Site

    University of Illinois at Chicago, Chicago, Illinois

    Run by

    University of Illinois at Chicago

    See if you can join NCT04547439 on ClinicalTrials.gov

25. Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature

    A prospective, multicenter evaluation of performance and safety of the Eversense Gemini System with flash glucose measurement feature. The purpose of this clinical investigation is to evaluate the accuracy of the Gemini System with new technological flash glucose monitoring (FGM) feature enhancemen…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Headlands Research - AMCR Institute, Escondido, California

    Run by

    Senseonics, Inc.

    See if you can join NCT07386340 on ClinicalTrials.gov