Diabetes Mellitus Clinical Trials

53 studies are recruiting for diabetes mellitus in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Early Tracking of Childhood Health Determinants (ETCHED) Study

   Background: Children s weight has increased sharply in recent years. This may put them at higher risk for health problems. High blood glucose in a pregnant mother and too much weight gain during pregnancy also may have long-term effects on the child s health. Children who become overweight or obese…

   Stage

   Not phased

   Ages

   0 to 99

   Site

   NIDDK, Phoenix, Phoenix, Arizona

   Run by

   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

   See if you can join NCT03481829 on ClinicalTrials.gov

2. Genetic Studies of Insulin and Diabetes

   The study will allow researchers to obtain blood, plasma, DNA, and RNA for genetic studies of insulin. There will be a focus on the causes of insulin resistance and diabetes mellitus. Insulin is a hormone found in the body that controls the level of sugar in the blood. Insulin resistance refers to …

   Stage

   Not phased

   Ages

   0 to 120

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

   See if you can join NCT00001987 on ClinicalTrials.gov

3. Prolongation of GLP-1 Adherence When Using Continuous Glucose Monitoring

   This study is to see if the FreeStyle Libre 3 Continuous Glucose Monitoring System (FSL3) will help prolong the length of time people with diabetes maintain adherence to glucagon-like peptide 1 (GLP-1/GIP) agonists.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Helios Clinical Research, Paradise Valley, Arizona

   Locations

   8 in total

   Run by

   Abbott Diabetes Care

   See if you can join NCT06668935 on ClinicalTrials.gov

4. Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease

   The aim of this clinical study is to 1) establish a healthy database for nuclear perfusion imaging of the lower extremities and 2) assess the prognostic value of radiotracer-based perfusion imaging for predicting clinical outcomes in patients with peripheral artery disease (PAD) who are undergoing …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Nationwide Children's Hospital, Columbus, Ohio

   Run by

   Nationwide Children's Hospital

   See if you can join NCT03622359 on ClinicalTrials.gov

5. Leveraging Artificial Intelligence to Prevent Vision Loss From Diabetes

   This pragmatic clinical trial is being conducted to test the effectiveness of AI-BRIDGE (Artificial Intelligence-Based point of caRe, Incorporating Diagnosis, SchedulinG, and Education), in improving screening and follow-up eye care compared to usual-care among patients with diabetes across 8 prima…

   Stage

   Not phased

   Ages

   22 and older

   Site

   UW School of Medicine and Public Health, Madison, Wisconsin

   Run by

   University of Wisconsin, Madison

   See if you can join NCT06763952 on ClinicalTrials.gov

6. Palatal Wound Healing After Free Gingival Graft Harvest in Diabetic Patients: A Clinical Trial

   The goal of this clinical trial is to evaluate local and systemic factors involved in palatal mucosal healing after Free Gingival Graft harvest in diabetic patients and to compare them with those in non-diabetic patients. Diabetic and non-diabetic volunteers of both sexes aged ≥ 18 years with gingi…

   Stage

   Not phased

   Ages

   18 and older

   Site

   College of Dentistry - University of Kentucky, Lexington, Kentucky

   Run by

   Mauro Santamaria

   See if you can join NCT07500935 on ClinicalTrials.gov

7. Impact GLP-1 Agonists Following Bariatric

   Glucagon-like peptide 1 (GLP-1) is a hormone that helps regulate blood glucose levels through improved insulin sensitivity and release of insulin from the pancreas, control hunger, induce satiety and plays a role in the metabolic health of a person. GLP-1 receptor agonists (GLP1-RAs) have been show…

   Stage

   Phase 4

   Ages

   18 and older

   Site

   University of Missouri Hospital, Columbia, Missouri

   Run by

   University of Missouri-Columbia

   See if you can join NCT06132477 on ClinicalTrials.gov

8. SPYRAL GEMINI Pilot Study

   The purpose of the SPYRAL GEMINI Pilot Study is to evaluate that multi-organ denervation with the Gemini System is safe and provide evidence of blood pressure reduction when studied in an uncontrolled hypertensive population with and without high cardiovascular risk.

   Stage

   Not phased

   Ages

   18 to 80

   Site

   Stanford Hospital and Clinics, Stanford, California

   Locations

   18 in total

   Run by

   Medtronic Vascular

   See if you can join NCT06907147 on ClinicalTrials.gov

9. A Novel Digital Tool Clinicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors

   The investigators will conduct a feasibility and pilot efficacy randomized controlled trial to test the usability and user satisfaction of an evidence-based digital health tool the investigators developed for clinicians to use to Prioritize Personalize Prescribe EXercise (P3-EX) to patients with ca…

   Stage

   Not phased

   Ages

   18 to 64

   Site

   Hartford HealthCare, Hartford, Connecticut

   Locations

   3 in total

   Run by

   University of Connecticut

   See if you can join NCT07238556 on ClinicalTrials.gov

10. A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer or Malignant Peritoneal Mesothelioma

    Participants will have a sample of their white blood cells, called T cells, collected using a procedure called leukapheresis. The collected T cells will be sent to a laboratory at Memorial Sloan Kettering to be changed (modified) to become MSLN-targeted CAR T cells, the CAR T-cell therapy that part…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey

    Locations

    7 in total

    Run by

    Memorial Sloan Kettering Cancer Center

    See if you can join NCT06623396 on ClinicalTrials.gov

11. American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

    Despite many advances in our understanding of the natural history and progression of chronic kidney disease (CKD) and cardio vascular disease (CVD) in the parent CRIC study over the past 15 years, important questions about key risk factors for these diseases remain unanswered in the AI population. …

    Stage

    Not phased

    Ages

    21 to 80

    Site

    First Nations Community Health Source, Albuquerque, New Mexico

    Locations

    3 in total

    Run by

    University of New Mexico

    See if you can join NCT04185844 on ClinicalTrials.gov

12. Total Contact Soft Cast in Diabetic Foot Ulcers

    To determine the effectiveness, compliance, patient tolerance, ease of use and safety of total contact soft cast in diabetic foot ulcers.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Minnesota, Minneapolis, Minnesota

    Run by

    University of Minnesota

    See if you can join NCT04210089 on ClinicalTrials.gov

13. AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

    The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight and type 2 diabetes. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111 (the trea…

    Stage

    Phase 3

    Ages

    18 and older

    Site

    Univ of Alabama Birmingham, Birmingham, Alabama

    Locations

    74 in total

    Run by

    Novo Nordisk A/S

    See if you can join NCT07533175 on ClinicalTrials.gov

14. FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)

    The goal of this clinical trial is to learn the best combination of family components that yields optimal weight loss among Black adults. The main question it aims to answer is: What combination of four family components in combination with a standard behavioral weight loss program yields optimal w…

    Stage

    Not phased

    Ages

    18 to 75

    Site

    University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

    Run by

    University of North Carolina, Chapel Hill

    See if you can join NCT06724406 on ClinicalTrials.gov

15. Inflammation, Diabetes, Ethnicity and Obesity Cohort

    Obesity affects over one third of US adults (>72 million, with BMI ≥30 kg/m2), and the proportion of US adults with BMI ≥40 kg/m2 has doubled in the last 20 years. Obesity is associated with increased mortality through its linkage to comorbidities including diabetes, hypertension, dyslipidemia, ost…

    Stage

    Not phased

    Ages

    18 to 75

    Site

    University of California San Francisco, San Francisco, California

    Run by

    University of California, San Francisco

    See if you can join NCT03022682 on ClinicalTrials.gov

16. Arizona CEAL: Linking Social Care With Healthcare Systems to Address SDOH

    The goal of the Arizona Community Engagement Alliance (AZ-CEAL) will be to combine social care with healthcare programs. The study will be connecting selected patients from clinics with trained community health workers (CHW) who will assist participants in getting the help that is needed for their …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Banner University Medical Center South, Tucson, Arizona

    Locations

    2 in total

    Run by

    Sairam Parthasarathy

    See if you can join NCT07799961 on ClinicalTrials.gov

17. Impact of Removable Cast Walker Design on Usability for Patients With Diabetic Foot Ulcers

    Within their lifetime, over 30% of people living with diabetes will develop a diabetic foot ulcer (DFU), many of which will never heal and may require amputation. Removable cast walkers (RCWs) are commonly prescribed to offload (treat) DFUs. While RCWs are prescribed to be worn during all weight be…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Rosalind Franklin University of Medicine and Science, North Chicago, Illinois

    Run by

    Rosalind Franklin University of Medicine and Science

    See if you can join NCT05415878 on ClinicalTrials.gov

18. Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis/Acute Pancreatitis Associated Diabetes Mellitus

    The purpose of this study is to evaluate efficacy of pioglitazone (PIO) versus empagliflozin (EMPA) to improve glycemic control in people with Chronic Pancreatitis (CP) or Recurrent Acute Pancreatitis (RAP) or Acute Pancreatitis (AP) associated with Diabetes Mellitus (DM). To evaluate mixed meal re…

    Stage

    Phase 2

    Ages

    18 to 80

    Site

    Mayo Clinic, Rochester, Minnesota

    Locations

    3 in total

    Run by

    Mayo Clinic

    See if you can join NCT06729996 on ClinicalTrials.gov

19. NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals

    Black individuals are more likely to have decreased insulin sensitivity which results in a high risk for the development of cardiometabolic disease. The reasons for this are incompletely understood. Natriuretic peptides (NPs) are hormones produced by the heart that play a role in regulating the met…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT04055428 on ClinicalTrials.gov

20. Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women

    The purpose of this study is to test a culturally tailored, smartphone-delivered intervention designed to increase physical activity and reduce risk for heart disease and type 2 diabetes among African American women.

    Stage

    Phase 2

    Ages

    24 to 65

    Site

    Arizona State University, Phoenix, Arizona

    Run by

    Arizona State University

    See if you can join NCT06337708 on ClinicalTrials.gov

21. Inpatient Use of Personal Continuous Glucose Monitor (CGM) to Improve Diabetes Mellitus Control

    The purpose of this research is to prove that data generated by your real-time personal continuous glucose monitors CGMs brought in the hospital at the time of hospitalization can be monitored and safely used to guide insulin therapy aiming to improve glycemic control and to diminish the hypoglycem…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Florida, Jacksonville, Florida

    Run by

    Mayo Clinic

    See if you can join NCT07006480 on ClinicalTrials.gov

22. Care Transitions App for Patients With Multiple Chronic Conditions

    The objective of this study is to widely implement and evaluate the Care Transitions App in a randomized controlled trial. The app the investigators designed for patients with multiple chronic conditions has four envisioned modules: 1) falls-reduction content, 2) a digital post-discharge transition…

    Stage

    Not phased

    Ages

    55 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Run by

    Brigham and Women's Hospital

    See if you can join NCT06051058 on ClinicalTrials.gov

23. SPARK-CGM Implementation

    Continuous glucose monitoring (CGM) is a technology that helps individuals with diabetes track their sugar levels in real-time, leading to more in-range blood sugars, fewer episodes of dangerously low blood sugar, and improved quality of life. Despite these benefits, CGM is not widely used in prima…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Montefiore Medical Group (MMG), The Bronx, New York

    Run by

    Montefiore Medical Center

    See if you can join NCT07548372 on ClinicalTrials.gov

24. Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery

    The goal of this randomized controlled trial is to compare the efficacy and safety of the iLet Bionic Pancreas (BP) System in adults with insulin-treated diabetes (type 1 diabetes or type 2 diabetes) compared to standard of care when ordered by primary care providers. The main question it aims to a…

    Stage

    Not phased

    Ages

    18 to 89

    Site

    University of Colorado Anschutz Medical Campus, Aurora, Colorado

    Locations

    2 in total

    Run by

    University of Colorado, Denver

    See if you can join NCT07011147 on ClinicalTrials.gov

25. Continuous Glucose Monitor for Mayo Clinic Advanced Care at Home Patients

    The purpose of this study is to measure differences in diabetes control with the use of continuous glucose monitor (CGM) and diabetes education compared with standard of care for glucose monitoring (glucometer checks) and diabetes education in participants with diabetes mellitus receiving therapy w…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Florida, Jacksonville, Florida

    Run by

    Mayo Clinic

    See if you can join NCT05880810 on ClinicalTrials.gov