Crohn's Disease Clinical Trials in Tyler, Texas

11 studies are recruiting for crohn's disease in Tyler, Texas right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

   The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. Study 1's primary hypotheses are that at least 1 tulisokibart dose level is superior to placebo in the proportion of participants achieving clinica…

   Stage

   Phase 3

   Ages

   16 to 80

   Site

   Tyler Research Institute ( Site 5001), Tyler, Texas

   Locations

   499 in total

   Run by

   Merck Sharp & Dohme LLC

   See if you can join NCT06430801 on ClinicalTrials.gov

2. A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

   The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with adalimumab or vedolizumab (VDZ) together with ustekinumab (UST) in adults with moderate to severe Crohn's Disease, and the effect of treatment with vedolizumab alone, after the dual …

   Stage

   Phase 4

   Ages

   18 to 70

   Site

   Tyler Research Institute, LLC, Tyler, Texas

   Locations

   48 in total

   Run by

   Takeda

   See if you can join NCT06045754 on ClinicalTrials.gov

3. A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

   This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of 3 active dose regimens of MORF-057 in adult study participants with moderately to severely active Crohn's disease (CD).

   Stage

   Phase 2

   Ages

   18 to 85

   Site

   Tyler Research Institute, LLC, Tyler, Texas

   Locations

   225 in total

   Run by

   Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

   See if you can join NCT06226883 on ClinicalTrials.gov

4. Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

   The main purpose of this study is to evaluate the efficacy and safety of mirikizumab and placebo compared with mirikizumab and concomitantly administered tirzepatide in adult participants with moderately to severely active CD and obesity, or overweight. The maximum duration of this study is up to 6…

   Stage

   Phase 3

   Ages

   18 to 70

   Site

   Tyler Research Institute, Tyler, Texas

   Locations

   183 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT06937099 on ClinicalTrials.gov

5. A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

   Crohn's disease (CD) is a long-lasting condition causing inflammation that can affect any part of the gut. The purpose of this study is to evaluate the efficacy and safety of TAK-279 versus placebo in participants with moderately to severely active Crohn's disease (CD). The main aim of this study i…

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   Tyler Research Institute, LLC, Tyler, Texas

   Locations

   190 in total

   Run by

   Takeda

   See if you can join NCT06233461 on ClinicalTrials.gov

6. An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

   This is a multinational, multicenter, randomized, double-blind, placebo-controlled, Phase 3 induction study, comprised of 3 sub-studies, to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active CD. Study details include: The study duration may be up to 35 …

   Stage

   Phase 3

   Ages

   16 to 80

   Site

   Tyler Research Institute, LLC: 8400095, Tyler, Texas

   Locations

   301 in total

   Run by

   Sanofi

   See if you can join NCT07184931 on ClinicalTrials.gov

7. Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

   Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most frequently affecting the bowels. It can cause many different symptoms including belly pain, diarrhea, tiredness, and weight loss. Treatments are available but do not work…

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   Tyler Research Institute /ID# 265545, Tyler, Texas

   Locations

   255 in total

   Run by

   AbbVie

   See if you can join NCT06548542 on ClinicalTrials.gov

8. A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

   This is a multicenter, randomized, double-blind, placebo-controlled, maintenance, Phase 3 study to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active Crohn's Disease (CD). Study details include: The study duration may be up to 286 weeks including: * 40-…

   Stage

   Phase 3

   Ages

   16 to 80

   Site

   Tyler Research Institute LLC-Site Number: 8400095, Tyler, Texas

   Locations

   35 in total

   Run by

   Sanofi

   See if you can join NCT07184944 on ClinicalTrials.gov

9. A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

   The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to vedolizumab only (also called monotherapy) in adults with moderately or severely active Crohn's Diseas…

   Stage

   Phase 3

   Ages

   18 to 65

   Site

   Tyler Research Institute, LLC, Tyler, Texas

   Locations

   138 in total

   Run by

   Takeda

   See if you can join NCT06227910 on ClinicalTrials.gov

10. A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)

    Crohn's Disease and Ulcerative Colitis are two types of inflammatory bowel disease (IBD), which is a serious, long-term condition in the gut (intestine) that can cause pain and swelling (inflammation) in the bowel. TAK-279 is a medicine which helps to block inflammation. This study is an extension …

    Stage

    Phase 2

    Ages

    18 to 75

    Site

    Tyler Research Institute, LLC, Tyler, Texas

    Locations

    16 in total

    Run by

    Takeda

    See if you can join NCT06764615 on ClinicalTrials.gov

11. A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

    This is a Phase 2, multicenter, platform study in adult participants with IBD (moderately to severely active Crohn's Disease or Ulcerative Colitis). The primary goal of this study is to assess the safety and efficacy of multiple investigational drugs.

    Stage

    Phase 2

    Ages

    18 to 80

    Site

    Mirador Therapeutics Selected Site, Tyler, Texas

    Locations

    66 in total

    Run by

    Mirador Therapeutics, Inc.

    See if you can join NCT07113522 on ClinicalTrials.gov