Colitis, Ulcerative Clinical Trials in Chapel Hill, North Carolina

5 studies are recruiting for colitis, ulcerative in Chapel Hill, North Carolina right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

   The purpose of this protocol is to evaluate the efficacy (how well it works), safety and tolerability of oral icotrokinra as therapy in adult and adolescent participants with moderately to severely active ulcerative colitis (UC, a chronic disease of the large intestine in which the lining of the co…

   Stage

   Phase 3

   Ages

   12 and older

   Site

   University of North Carolina, Chapel Hill, North Carolina

   Locations

   401 in total

   Run by

   Janssen Research & Development, LLC

   See if you can join NCT07196748 on ClinicalTrials.gov

2. A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically

   The purpose of this post-marketing study is to assess the amount of guselkumab in breast milk of lactating women receiving guselkumab as part of their standard clinical care provided by their treating physician, for any of the approved indications.

   Stage

   Phase 4

   Ages

   18 and older

   Site

   University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

   Run by

   Janssen Research & Development, LLC

   See if you can join NCT07654751 on ClinicalTrials.gov

3. A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

   This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active ulcerative colitis (UC). The primary goal of the study is to assess the efficacy and safety of multiple interventions following intravenous (IV) induction and subcutaneous (SC) m…

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   040, Chapel Hill, North Carolina

   Locations

   267 in total

   Run by

   Spyre Therapeutics, Inc.

   See if you can join NCT07012395 on ClinicalTrials.gov

4. A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

   The purpose of this study is to evaluate the effectiveness and safety of ozanimod (RPC1063) in achieving and maintaining clinical remission. Ozanimod will be administered orally to pediatric participants with moderate to severe active ulcerative colitis (UC) who have had an inadequate response to c…

   Stage

   Phase 2

   Ages

   2 to 17

   Site

   University of North Carolina Medical Center, Chapel Hill, North Carolina

   Locations

   90 in total

   Run by

   Bristol-Myers Squibb

   See if you can join NCT05076175 on ClinicalTrials.gov

5. An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

   The purpose of this observational study is to learn about the effects of etrasimod as a treatment for adult patients with moderate to severe ulcerative colitis. Patients will be treated according to standard of care and will only be included in the study if etrasimod is the best treatment of choice…

   Stage

   Not phased

   Ages

   18 to 64

   Site

   University of North Carolina at Chapel Hill, Division of Gastroenterology and Hepatology, Chapel Hill, North Carolina

   Locations

   28 in total

   Run by

   Pfizer

   See if you can join NCT06398626 on ClinicalTrials.gov