Cognition Clinical Trials

26 studies are recruiting for cognition in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Effects of Beef-Forward Ready-to-Eat Meals on Recovery Following Simulated Fire Suppression Activities

   This clinical trial aims to determine whether consuming beef-based protein before and after physically demanding simulated firefighting activities improves recovery, physical performance, and cognitive performance in healthy adult firefighters. The study will also compare beef-based protein meals w…

   Stage

   Not phased

   Ages

   18 to 60

   Site

   Bob Bolen Public Safety Complex Administration, Fort Worth, Texas

   Locations

   2 in total

   Run by

   Sam Houston State University

   See if you can join NCT07822048 on ClinicalTrials.gov

2. Effects of Pork Protein on Recovery Following Simulated Fireground Activity

   The goal of this clinical trial is to learn whether consuming pork-based protein before and after physically demanding simulated firefighting activities can improve recovery, physical performance, and cognitive performance in healthy adult firefighters. The study will also compare pork-based protei…

   Stage

   Not phased

   Ages

   18 to 60

   Site

   Bob Bolen Public Safety Complex Administration, Fort Worth, Texas

   Locations

   2 in total

   Run by

   Sam Houston State University

   See if you can join NCT07819565 on ClinicalTrials.gov

3. Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure

   The purpose of the study is to determine the effectiveness of wild blueberries on cardiovascular health, cognitive function, and gut microbiota composition in non-Hispanic Black and White adults with elevated blood pressure.

   Stage

   Not phased

   Ages

   45 to 65

   Site

   Georgia State University, Atlanta, Georgia

   Run by

   Georgia State University

   See if you can join NCT06735599 on ClinicalTrials.gov

4. Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

   The goal of this clinical trial is to determine the effectiveness of using a freeze-dried wild blueberry powder on cardiometabolic health, cognitive function, and gut microbiota composition in adult women with prediabetes.

   Stage

   Not phased

   Ages

   20 to 65

   Site

   Georgia State University, Atlanta, Georgia

   Run by

   Georgia State University

   See if you can join NCT06735651 on ClinicalTrials.gov

5. Peanuts for Cardiometabolic, Brain, and Intestinal Health

   The overall objective of this 14-month randomized crossover study is to seek evidence demonstrating that daily consumption of peanuts and peanut products improve cardiometabolic, cognitive, and intestinal health in a racially diverse prediabetes population.

   Stage

   Not phased

   Ages

   20 to 59

   Site

   Georgia State University, Atlanta, Georgia

   Run by

   Georgia State University

   See if you can join NCT06867198 on ClinicalTrials.gov

6. Targeted Assessment of Cognition and Tactical-performance With Ingested Ketones

   The goal of this study is to determine whether consuming a commercially available exogenous ketone supplement (KetoneIQ®) affects cognition, specifically marksmanship, under physical stress (i.e., exhaustive exercise). The main questions we seek to answer are: * Does the supplement save cognitive p…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Institute of Sports Sciences and Medicine, Tallahassee, Florida

   Run by

   Florida State University

   See if you can join NCT07771790 on ClinicalTrials.gov

7. LpD3.5 Intervention Study in Older Adults- LISA-I Trial

   This randomized placebo-controlled clinical study, called the LpD3.5 Intervention Study in Older Adults (LISA), aims to evaluate whether a heat-inactivated postbiotic of human origin (LpD3.5) can serve as a non-pharmacological intervention to reduce gut permeability and inflammation in older adults…

   Stage

   EARLY_Phase 1

   Ages

   60 and older

   Site

   Department of Neurosurgery and Brain and Spine and Faculty of USF Center for Microbiome Re-search, Microbiomes Institute, Tampa, Florida

   Run by

   University of South Florida

   See if you can join NCT07794956 on ClinicalTrials.gov

8. Appetite and Cognition Response to a Breakfast Cereal

   The purpose of this study is to examine appetite and cognition responses following consumption of a ready-to-eat breakfast cereal.

   Stage

   Not phased

   Ages

   18 to 70

   Site

   Remote, Minneapolis, Minnesota

   Run by

   General Mills

   See if you can join NCT07782229 on ClinicalTrials.gov

9. Establishing Normal Cognitive Test Scores for Adults Using a Voice-Enabled Digital Testing Platform Across the Lifespan

   Trial weblink: https://www.memoryexam.com/job/norms/ Participants enrolled in this study will complete a single-session, non-invasive, computerized cognitive assessment administered through a secure, web-based digital platform. The purpose of the study is to establish normative cognitive performanc…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   The Neurology Center of Southern California, Carlsbad, California

   Run by

   The Neurology Center of Southern California

   See if you can join NCT07763392 on ClinicalTrials.gov

10. Interventions in Mathematics and Cognitive Skills

    The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning disabilities (MLD).

    Stage

    Not phased

    Ages

    6 to 12

    Site

    Stanford Cognitive and Systems Neuroscience Laboratory, Palo Alto, California

    Run by

    Stanford University

    See if you can join NCT05201534 on ClinicalTrials.gov

11. The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study

    This project uses a hybrid trial design to evaluate two biomedical interventions targeting the gut-brain axis. One intervention is portable Transcutaneous Vagus Nerve Stimulator, tVNS, that is hypothesized to stimulate the autonomic nervous system, resulting in decreased inflammation and improved c…

    Stage

    Not phased

    Ages

    35 to 70

    Site

    University of Miami, Coral Gables, Florida

    Run by

    University of Florida

    See if you can join NCT05090267 on ClinicalTrials.gov

12. Cognitive Strategies in Early Psychosis 2

    The goal of this clinical trial is to learn more about decision making in psychosis spectrum disorders, like schizophrenia. Participants will be people who have had symptoms of a psychosis spectrum disorder start within the last five years. The investigators will study how two study agents change d…

    Stage

    Phase 3

    Ages

    18 to 35

    Site

    University of Minnesota, Minneapolis, Minnesota

    Run by

    University of Minnesota

    See if you can join NCT07263022 on ClinicalTrials.gov

13. Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome

    The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function, dual task standing and walking, and other metrics of mobility in older a…

    Stage

    Not phased

    Ages

    65 to 90

    Site

    Hebrew Rehabilitation Center, Roslindale, Massachusetts

    Locations

    2 in total

    Run by

    Hebrew SeniorLife

    See if you can join NCT06821568 on ClinicalTrials.gov

14. Exercise and Intranasal Insulin in Type 2 Diabetes

    About 6.5 million adults in the United States who are 65 or older have dementia. While the exact cause of dementia is not known, it may be due to changes in the brain. Further, risk may be higher when the brain does not respond to insulin. Indeed, brain insulin resistance has emerged as a pathologi…

    Stage

    Phase 2

    Ages

    55 to 80

    Site

    Robert Wood Johnson University Hospital Clinical Research Center, New Brunswick, New Jersey

    Locations

    4 in total

    Run by

    Rutgers, The State University of New Jersey

    See if you can join NCT07675499 on ClinicalTrials.gov

15. Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury

    This study applies a hypothesis-driven approach to examine the effects of chronic marijuana use on HIV-associated inflammation and its subsequent impacts on central nervous system function, with the goal of identifying the mechanisms through which cannabinoids modulate neurological disorders and ot…

    Stage

    Not phased

    Ages

    25 to 59

    Site

    Biotech Place, Winston-Salem, North Carolina

    Run by

    Wake Forest University Health Sciences

    See if you can join NCT04810858 on ClinicalTrials.gov

16. Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters

    The purpose of this pilot study is to examine the feasibility and acceptability of an app-based sleep program designed to help firefighters improve their sleep.

    Stage

    Not phased

    Ages

    18 and older

    Site

    California Polytechnic University - San Luis Obispo, San Luis Obispo, California

    Run by

    California Polytechnic State University-San Luis Obispo

    See if you can join NCT07477184 on ClinicalTrials.gov

17. Cognitive Strategies in Early Psychosis 1

    The goal of this clinical is to learn more about decision making in psychosis spectrum disorders, like schizophrenia. The investigators will ask people who do not have psychosis to take a single dose of modafinil and then complete some brain games on the computer that measure decision making. They …

    Stage

    Phase 3

    Ages

    18 to 35

    Site

    University of Minnesota, Minneapolis, Minnesota

    Run by

    University of Minnesota

    See if you can join NCT07231497 on ClinicalTrials.gov

18. Nutrition to Support Postoperative Recovery

    Older surgical patients commonly have malnutrition, and there is evidence these patients have increased risk for poor physical and brain recovery after surgery and anesthesia. There are scientific-based recommendations to provide nutritional supplements to support recovery. However, to date these r…

    Stage

    Not phased

    Ages

    70 and older

    Site

    Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

    Run by

    Dartmouth-Hitchcock Medical Center

    See if you can join NCT07109505 on ClinicalTrials.gov

19. The Effect of Near-infrared Light Therapy on Brain Function and Cognition in Young and Older Adults

    The goal of this pilot clinical trial is to test whether transcranial photobiomodulation (tPBM), a non-invasive brain stimulation technique using near-infrared light, can improve brain blood flow regulation (neurovascular coupling) and cognitive function in older adults. The main questions it aims …

    Stage

    Not phased

    Ages

    21 to 85

    Site

    University of Oklahoma Health Campus, Oklahoma City, Oklahoma

    Run by

    University of Oklahoma

    See if you can join NCT07209683 on ClinicalTrials.gov

20. Tennessee Alzheimer's Project

    The primary objective of the Vanderbilt Alzheimer's Disease Research Center (VADRC) is to provide local and national researchers with access to a well-characterized and diverse clinical cohort, including participant referrals, biosamples, clinical data, and neuroimaging data. The VADRC Clinical Cor…

    Stage

    Not phased

    Ages

    60 and older

    Site

    Vanderbilt University Medical Center, Nashville, Tennessee

    Run by

    Vanderbilt University Medical Center

    See if you can join NCT05372172 on ClinicalTrials.gov

21. Identifying the Neural Correlates of Mental Simulation in Multi-Step Planning

    Planning is the ability to think ahead by considering possible future actions and their consequences. This research study aims to understand how the brain supports multi-step planning by testing whether people simulate promising future move sequences while deciding what to do next. Healthy adult vo…

    Stage

    Not phased

    Ages

    18 to 64

    Site

    New York University, New York, New York

    Run by

    New York University

    See if you can join NCT07293637 on ClinicalTrials.gov

22. A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers

    The goal of this clinical trial is to evaluate whether a home-based mHealth intervention can improve adherence to the 24-Hour Movement Guidelines in preschool-aged children (3-4 years old) who currently meet 0 or 1 of the guidelines for physical activity, sedentary behavior, and sleep. The main que…

    Stage

    Not phased

    Ages

    3 to 4

    Site

    University of Kansas Medical Center, Kansas City, Kansas

    Run by

    University of Kansas Medical Center

    See if you can join NCT06667661 on ClinicalTrials.gov

23. Cognitive Vitality Pilot Study

    This study's purpose is to evaluate the effects of a dietary supplement on cognitive function and psychological well-being in community-dwelling older adults aged 55+. The study involves taking a commercially available dietary supplement daily for 45 days. A 45-minute assessment will be conducted a…

    Stage

    Not phased

    Ages

    55 and older

    Site

    Community, West Palm Beach, Florida

    Run by

    Arizona State University

    See if you can join NCT07208279 on ClinicalTrials.gov

24. Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD

    Veterans with mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD) commonly experience cognitive impairments including attention and executive function deficits that interfere with their ability to engage in productive personal and social activities. Of the limited intervent…

    Stage

    Not phased

    Ages

    30 to 55

    Site

    North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville, Florida

    Run by

    VA Office of Research and Development

    See if you can join NCT05380050 on ClinicalTrials.gov

25. INTEGRATED CHILDHOOD ACTIVITY AND NUTRITION (ICAN) STUDY

    This study is a multi-functional integrated research and education project to prevent losses in academic achievement, cognitive function, and behavioral health among at-risk youth. The study tests the effects of a 8-week nutrition and physical activity-based program (Integrated Childhood Activity a…

    Stage

    Not phased

    Ages

    6 to 11

    Site

    Bloomington Public Schools District 87, Bloomington, Illinois

    Run by

    University of Illinois at Urbana-Champaign

    See if you can join NCT07011602 on ClinicalTrials.gov