Chronic Myelomonocytic Leukemia Clinical Trials in Miami, Florida

4 studies are recruiting for chronic myelomonocytic leukemia in Miami, Florida right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia.

   To learn if olutasidenib can help to control CCUS, MDS, and/or CMML. The safety of the drug will also be studied.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   University of Miami, Miami, Florida

   Locations

   2 in total

   Run by

   M.D. Anderson Cancer Center

   See if you can join NCT06566742 on ClinicalTrials.gov

2. Chimeric Antigen Receptor T Cell Therapy Redirected to CD4 (CD4CAR)as a Second Line Treatment for Chronic Myelomonocytic Leukemia, CMML.

   This study is designed as a single arm open label traditional Phase I, 3+3, study of CD4-directed chimeric antigen receptor engineered T-cells (CD4CAR) in subjects with relapsed or refractory CMML. Specifically, the study will evaluate the safety and feasibility of CD4CAR T-cells.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida 33136, Miami, Florida

   Locations

   4 in total

   Run by

   Huda Salman

   See if you can join NCT06071624 on ClinicalTrials.gov

3. A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

   Study ASTX030-01 is a multi-phase study comprising of Phases 1-3 Monotherapy arms, and Phase 1 and Phase 2 Combination Therapy arms. Phase 1 Monotherapy consists of an open-label Dose Escalation Stage (Stage A) using multiple cohorts at escalating dose levels of oral cedazuridine and azacitidine (o…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   University of Miami - Sylvester Comprehensive Cancer Center, Miami, Florida

   Locations

   71 in total

   Run by

   Taiho Oncology, Inc.

   See if you can join NCT04256317 on ClinicalTrials.gov

4. Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia

   The main purpose of this study is to identify a safe and potentially effective dose of tuspetinib to be used in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelodysplastic syndromes with increased blasts grade 2 (MDS-IB2), or chronic myelomonocytic leukemia (CM…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   University of Miami - Miller School of Medicine, Miami, Florida

   Locations

   34 in total

   Run by

   Aptose Biosciences Inc.

   See if you can join NCT03850574 on ClinicalTrials.gov