Chronic Kidney Disease Clinical Trials

35 studies are recruiting for chronic kidney disease in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease: Sympatholysis in CKD

   The goals of this project are to investigate the mechanisms and potential therapies related to exercise capacity in persons with chronic kidney disease (CKD).

   Stage

   Phase 2

   Ages

   40 to 75

   Site

   Emory Clinic, Atlanta, Georgia

   Locations

   2 in total

   Run by

   Emory University

   See if you can join NCT05928936 on ClinicalTrials.gov

2. A Natural History Study of Metabolic Sizing in Health and Disease

   Background: Scientists have long used simple measures (such as height and weight) to estimate how much a person s body uses food (calories) as energy, as commonly called the metabolic rate. But metabolism varies among people with similar body sizes. Scientists now believe the old formulas for estim…

   Stage

   Not phased

   Ages

   2 to 99

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

   See if you can join NCT05398783 on ClinicalTrials.gov

3. The KidneyCARE (Community Access to Research Equity) Study

   For chronic kidney disease (CKD), there is a lack of unique and powerful platform for patient engagement, research studies and public health advocacy work. The National kidney Foundation (NKF) launched the first nationwide registry for people at all stages and types of CKD, including people on dial…

   Stage

   Not phased

   Ages

   18 to 120

   Site

   Geisinger Clinic, Danville, Pennsylvania

   Run by

   Tufts Medical Center

   See if you can join NCT05497518 on ClinicalTrials.gov

4. Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias

   The researchers are trying to find out more about Gastric Antral Vascular Ectasia (GAVE). This is a condition that affects the blood vessels in the stomach, leading to their enlargement and possible bleeding. It can also cause symptoms such as abdominal pain and nausea. By participating in this stu…

   Stage

   Not phased

   Ages

   19 and older

   Site

   Mayo Clinic, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT06306963 on ClinicalTrials.gov

5. A Study of Luspatercept in People With Anemia

   The researchers are doing this study to test whether luspatercept works to improve hemoglobin levels in people with anemia caused by chronic kidney disease (CKD). The researchers will also test whether luspatercept is a safe treatment that causes few or mild side effects in participants.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey

   Locations

   7 in total

   Run by

   Memorial Sloan Kettering Cancer Center

   See if you can join NCT07725497 on ClinicalTrials.gov

6. CKD Awareness, Referrals, Education, and Support Intervention for Early-Stage CKD

   The goal of this pilot clinical trial is to learn if an intervention delivering education, motivational support, and social support can prevent worsening kidney disease in adults with diabetes and early-stage kidney disease. The main questions it aims to answer are: 1. Is this intervention feasible…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Illinois Chicago Hospital, Chicago, Illinois

   Run by

   University of Illinois at Chicago

   See if you can join NCT07210710 on ClinicalTrials.gov

7. A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease

   The goal of this clinical trial is to observe the safety of IGT-303 in healthy volunteers and participants with Chronic Kidney Disease. The main question it aims to answer is: Is IGT-303 safe as a single dose or multiple dose regimen when applied under the skin (subcutaneously (SC)) or to a vein (i…

   Stage

   Phase 1

   Ages

   18 to 75

   Site

   Nucleus Network, Herston, Brisbane

   Locations

   13 in total

   Run by

   Ingenia Therapeutics INC

   See if you can join NCT07231679 on ClinicalTrials.gov

8. A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

   Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria, a condition in which a person´s kidneys leak protein into the urine. The kidneys filter waste and fluid from the blood to form urine. In children wit…

   Stage

   Phase 3

   Ages

   1 to 18

   Site

   Hospital General de Ninos Ricardo Gutierrez | Pediatric Nephrology Department, Buenos Aires,

   Locations

   151 in total

   Run by

   Bayer

   See if you can join NCT05457283 on ClinicalTrials.gov

9. Lifestyle Intervention In CKD

   This research study will test whether a 12-week healthy lifestyle program offered through a cardiac rehabilitation center can help lower blood pressure and improve kidney health in adults with advanced chronic kidney disease. Participants will be randomly assigned to either routine kidney health ed…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Sarah W Stedman Nutrition & Metabolism Center, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT07633145 on ClinicalTrials.gov

10. Feasibility of The Health Integrated Nutrition and Kidney Wellness Program

    Purpose of the Study: This clinical trial will test whether a nutrition and kidney health program can work well for adults with kidney disease. The program was created with help from patients and community partners. Main Questions: How many eligible patients choose to join the program? How many par…

    Stage

    Not phased

    Ages

    18 and older

    Site

    UPMC Kidney Clinic - Wexford, Pittsburgh, Pennsylvania

    Locations

    5 in total

    Run by

    University of Pittsburgh

    See if you can join NCT07518719 on ClinicalTrials.gov

11. A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.

    This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled multicenter study to investigate outcomes with elecoglipron compared with placebo in participants with CKD with and without T2DM who are on background SGLT2i (dapagliflozin) as GDMT and other SoC treatments for CKD.

    Stage

    Phase 3

    Ages

    18 and older

    Site

    Research Site, Minneapolis, Minnesota

    Locations

    715 in total

    Run by

    AstraZeneca

    See if you can join NCT07753993 on ClinicalTrials.gov

12. Pivotal Study of the Velocity™ pAVF System

    This study will evaluate the Velocity Percutaneous Arteriovenous Fistula (pAVF) System, a new minimally invasive method for creating dialysis access. People with kidney failure often require dialysis, which depends on having a reliable arteriovenous fistula (AVF). Traditionally, AVFs are created wi…

    Stage

    Not phased

    Ages

    18 to 80

    Site

    Trinity Research Group, Dothan, Alabama

    Locations

    13 in total

    Run by

    Venova Medical

    See if you can join NCT07153939 on ClinicalTrials.gov

13. Breakthrough - T1DM and Chronic Kidney Disease

    Single arm- subject treated with Tegoprubart and everolimus. The purpose of this research is to gather information on the safety and effectiveness of investigational regimen containing 2 experimental components: * An investigational drug called Tegoprubart and * Human pancreatic islet cells Both Te…

    Stage

    Phase 1

    Ages

    18 to 70

    Site

    Diabetes Research Institute, University of Miami, Miami, Florida

    Locations

    2 in total

    Run by

    University of Chicago

    See if you can join NCT07592000 on ClinicalTrials.gov

14. Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease

    The purpose of this first-in-human (FIH) study is to evaluate safety, tolerability, pharmacokinetic (PK) of OJR520.

    Stage

    Phase 1

    Ages

    18 to 65

    Site

    Quotient Sciences Sea View, Miami, Florida

    Locations

    2 in total

    Run by

    Novartis Pharmaceuticals

    See if you can join NCT07235059 on ClinicalTrials.gov

15. A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort

    This study will evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of single ascending doses (SAD) and multiple ascending doses (MAD) of AZD4248 administered as an oral solution and intravenous (IV) infusion. Additionally, the study investigates the non-interventional f…

    Stage

    Phase 1

    Ages

    18 to 75

    Site

    Research Site, Glendale, California

    Locations

    5 in total

    Run by

    AstraZeneca

    See if you can join NCT07024823 on ClinicalTrials.gov

16. Staged Kidney Transplantation During Combined Heart/Kidney Transplantation

    The primary purpose of this study is to evaluate the safety and efficacy of ex vivo machine perfusion with staged implantation of kidney allografts during combined heart/kidney transplantation.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Cedars-Sinai Medical Center, Los Angeles, California

    Run by

    Cedars-Sinai Medical Center

    See if you can join NCT06877169 on ClinicalTrials.gov

17. Renal Impairment Study for Oral EC5026

    The goal of this Phase 1 clinical trial is to assess single dose pharmacokinetics of oral EC5026 in a population with chronic kidney disease. The main questions it aims to answer are: 1. To determine if the PK of a single 8 mg dose of EC5026, administered orally, in adult participants with varying …

    Stage

    Phase 1

    Ages

    55 and older

    Site

    UC Davis Medical Center, Sacramento, California

    Run by

    EicOsis Human Health Inc.

    See if you can join NCT07694544 on ClinicalTrials.gov

18. An Observational Study Called FINEROD to Learn More About the Use of the Treatment Finerenone Including How Safe it is and How Well it Works Under Real-world Conditions

    This is an observational study, in which data from people in Asia and in the United States with chronic kidney disease (CKD) together with type 2 diabetes (T2D) are studied. The participants in this study are already receiving the study treatment finerenone as part of their regular care from their …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Bayer, Berlin,

    Locations

    4 in total

    Run by

    Bayer

    See if you can join NCT06278207 on ClinicalTrials.gov

19. Adia Med of Winter Park LLC Chronic Kidney Disease Research Study

    The goal of this clinical trial is to learn whether a new regenerative treatment called AdiaVita, made from umbilical cord blood-derived stem cells and exosomes combined with glutathione, is safe and can help improve kidney function in adults with chronic kidney disease (CKD). In this condition, th…

    Stage

    Phase 1

    Ages

    18 to 80

    Site

    Adia Med Of Winter Park, Winter Park, Florida

    Run by

    Adia Med of Winter Park LLC

    See if you can join NCT07572890 on ClinicalTrials.gov

20. Safety of Short-course of NSAIDs in Pediatric Patients With CKD

    The purpose of this study is to determine if non-steroidal anti-inflammatory (NSAID) use in the postoperative setting increases the risk of acute kidney injury (AKI) in pediatric patients with mild-to-moderate chronic kidney disease (CKD). The investigators hypothesize that there is no increased ri…

    Stage

    Phase 4

    Ages

    1 to 25

    Site

    Children's Hospital Colorado, Aurora, Colorado

    Run by

    University of Colorado, Denver

    See if you can join NCT06860711 on ClinicalTrials.gov

21. Proteogenomic Monitoring and Assessment of Liver Transplant Recipients

    This study is being done to test blood, urine and tissue samples to see if this can help decide if CKD (Chronic Kidney Disease), AR (Acute Rejection) and HCV (Hepatitis C Virus) can be identified in its early stages. CKD damage to the kidneys, AR and HCV all lower the body's ability to function pro…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Northwestern Memorial Hospital, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT01644903 on ClinicalTrials.gov

22. Sympatholysis in Chronic Kidney Disease

    The purpose of this study is to find out why patients with chronic kidney disease (CKD) have poor exercise capacity and what causes an increase in blood pressure during exercise (i.e. increased adrenaline levels, or decreased ability of blood vessels to dilate).

    Stage

    Phase 1

    Ages

    18 to 75

    Site

    Atlanta VA Medical Center, Decatur, Georgia

    Run by

    Emory University

    See if you can join NCT02411773 on ClinicalTrials.gov

23. Empagliflozin Treatment in Kidney Transplant Recipients

    Kidney transplantation improves the health and quality of life for those Veterans with end stage kidney disease (ESKD). While early patient and graft survival are excellent, long-term outcomes continue to be challenging. Patient death with existing kidney graft function occurs in about half of all …

    Stage

    Phase 4

    Ages

    19 and older

    Site

    Edward Hines Jr. VA Hospital, Hines, IL, Hines, Illinois

    Locations

    5 in total

    Run by

    VA Office of Research and Development

    See if you can join NCT06013865 on ClinicalTrials.gov

24. Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)

    The Division of Kidney, Urologic, and Hematologic Diseases (DKUHD) of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), in collaboration with the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the National Heart, Lung and Bloo…

    Stage

    Not phased

    Ages

    0 to 22

    Site

    Children's Mercy Kansas City, Kansas City, Missouri

    Locations

    2 in total

    Run by

    Johns Hopkins Bloomberg School of Public Health

    See if you can join NCT00327860 on ClinicalTrials.gov

25. Sickle Cell Kidney Biorepository

    Kidney disease is a major cause of illness and death in people with sickle cell disease and sickle cell trait. Despite these concerning facts, we do not (1) have an in-depth understanding of how kidney disease starts in sickle cell disease and sickle cell trait, (2) have detailed insights into why …

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Parkland Memorial Hospital, Dallas, Texas

    Locations

    2 in total

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT07064174 on ClinicalTrials.gov