Chemotherapy-induced Peripheral Neuropathy Clinical Trials

16 studies are recruiting for chemotherapy-induced peripheral neuropathy in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Study of SIR2501 in Solid Tumor Patients Receiving Paclitaxel

   This Phase 2, open-label study will evaluate the safety, tolerability, and pharmacokinetics of SIR2501 in adults with solid tumors who are scheduled to receive paclitaxel-based chemotherapy. The study will also explore whether SIR2501 has the potential to reduce the development of chemotherapy-indu…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Research site, Baltimore, Maryland

   Locations

   2 in total

   Run by

   Sironax USA, Inc.

   See if you can join NCT07765446 on ClinicalTrials.gov

2. Exploring the Benefit of Peripheral Nerve Stimulation in Treating Pain From Chemo-induced Peripheral Neuropathy: A Longitudinal Single Center Feasibility Study

   To learn if peripheral nerve stimulation (PNS) can help to improve pain in participants with CIPN.

   Stage

   Not phased

   Ages

   18 to 85

   Site

   MD Anderson Cancer Center, Houston, Texas

   Run by

   M.D. Anderson Cancer Center

   See if you can join NCT06162403 on ClinicalTrials.gov

3. Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy

   This research study is for people who have a condition called chemotherapy-induced peripheral neuropathy (CIPN). This condition develops as a result of receiving medication(s) to treat cancer, particularly chemotherapy. CIPN is characterized by pain, numbness, tingling or burning sensations, typica…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute, Cleveland, Ohio

   Run by

   Case Comprehensive Cancer Center

   See if you can join NCT07219472 on ClinicalTrials.gov

4. Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life With Chemotherapy-Induced Peripheral Neuropathy

   This study examines how spinal cord stimulation (SCS) affects pain level and quality of life in patients experiencing chemotherapy-induced peripheral neuropathy (CIPN). CIPN is a nerve problem and one of the potential side effects of chemotherapy that causes pain, numbness, tingling, swelling, or m…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT05411523 on ClinicalTrials.gov

5. Physiologic Measure of VIPN

   The purpose of this study is the development of a physiologic endpoint using a novel technology that would provide an objective, easy to use and more sensitive assessment of VIPN in children and adolescents. The ability to more easily detect and monitor VIPN, even before it is clinically evident, w…

   Stage

   Not phased

   Ages

   6 to 18

   Site

   Children's National Health System, Washington D.C., District of Columbia

   Run by

   Children's National Research Institute

   See if you can join NCT04786977 on ClinicalTrials.gov

6. VGAIT for Chemotherapy-induced Peripheral Neuropathy

   Perform a feasibility study on imagined acupuncture treatment of Chemotherapy-induced peripheral neuropathy (CIPN)

   Stage

   Not phased

   Ages

   18 to 80

   Site

   Massachusetts General Hospital, Charlestown, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT07177820 on ClinicalTrials.gov

7. Self-applied taVNS for CIPN

   The purpose of this study is to determine the feasibility of using a portable device at home to self-administer transcutaneous auricular vagus nerve stimulation (taVNS). This handheld device has two small electrodes that are placed on specific areas of the outer ear. This device delivers a mild ele…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   University of Miami, Plumer Building, Coral Gables, Florida

   Run by

   University of Miami

   See if you can join NCT07596030 on ClinicalTrials.gov

8. A Virtually Delivered Diet Intervention (LASO-3) for the Improvement of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors Post-treatment

   This clinical trial studies whether a virtually delivered diet intervention focused on lower added sugar, higher fiber, and higher omega 3 fatty acid (LASO-3) can be used to improve chemotherapy-induced peripheral neuropathy (CIPN) in cancer survivors after treatment. Cancer survivors often experie…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Michigan Rogel Cancer Center, Ann Arbor, Michigan

   Run by

   University of Michigan Rogel Cancer Center

   See if you can join NCT07365007 on ClinicalTrials.gov

9. Light Therapy for Chemotherapy Induced Peripheral Neuropathy in Childhood Cancer Survivors

   The purpose of this study is to determine feasibility and acceptability of a six-week at-home light therapy protocol in childhood cancer survivors, to identify facilitators and barriers to implementing this intervention, and to measure signs and symptoms of Chemotherapy Induced Peripheral Neuropath…

   Stage

   Not phased

   Ages

   5 and older

   Site

   Yale New Haven Health Smilow York Street Hospital, New Haven, Connecticut

   Locations

   2 in total

   Run by

   Yale University

   See if you can join NCT07019259 on ClinicalTrials.gov

10. Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer - COHORT 2

    The investigators aim to determine the effect of cryotherapy wraps plus compression therapy (henceforth referred to as cryocompression) versus cryotherapy wraps alone on the incidence and degree of chemotherapy-induced peripheral neuropathy in patients with gynecologic cancer using a noninferiority…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Middlesex Health Cancer Center - Middletown, Middletown, Connecticut

    Locations

    4 in total

    Run by

    Duke University

    See if you can join NCT06139458 on ClinicalTrials.gov

11. Understanding and Preventing Cortical Mechanisms of Chemotherapy-induced Peripheral Neuropathy

    Cohort 1: To track the onset and progression of a condition called chemotherapy-induced peripheral neuropathy (CIPN). Cohort 2: To track the onset and progression of a condition called chemotherapy-induced peripheral neuropathy (CIPN) and to test a certain type of experimental neuromodulation (stim…

    Stage

    Not phased

    Ages

    18 and older

    Site

    MD Anderson Cancer Center, Houston, Texas

    Run by

    M.D. Anderson Cancer Center

    See if you can join NCT06389721 on ClinicalTrials.gov

12. CBG/CBD Oil for Chemotherapy-Induced Peripheral Neuropathy

    The goal of this clinical trial is to learn if a commercially available cannabigerol (CBG)/cannabidiol (CBD) oil is safe, feasible to use, and can help reduce symptoms of chemotherapy-induced peripheral neuropathy (CIPN) in adults who have completed platinum-based chemotherapy for gastrointestinal …

    Stage

    Phase 1

    Ages

    21 and older

    Site

    Penn State Cancer Institute, Hershey, Pennsylvania

    Run by

    Milton S. Hershey Medical Center

    See if you can join NCT07016971 on ClinicalTrials.gov

13. Cryocompression for CIPN

    This study aims to evaluate the effectiveness, tolerability, and safety of using cooling therapy and pressure (cryocompression) to reduce peripheral neuropathy, a condition affecting the nerves supplying the arms and legs (limbs) resulting in possible numbness, pain, and/or loss of motor function, …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Dana-Farber Cancer Institute, Boston, Massachusetts

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT07064798 on ClinicalTrials.gov

14. Remote Monitoring and Management of Chemotherapy Induced Peripheral Neuropathy

    This is a prospective randomized trial designed to investigate a new care model for patients who suffer from nerve damage from chemotherapy called chemotherapy induced peripheral neuropathy (CIPN). All participants in the study will report their CIPN symptoms daily using a website, app or phone for…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Utah, Salt Lake City, Utah

    Locations

    3 in total

    Run by

    University of Vermont

    See if you can join NCT04763356 on ClinicalTrials.gov

15. Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

    This phase II trials evaluates how well different types of phytocannabinoids (cannabidiol [CBD] versus tetrahydrocannabinol [THC] and CBD formulation [THC:CBD]) work to reduce chronic chemotherapy-induced peripheral neuropathy among breast and colon cancer survivors. Chemotherapy induced peripheral…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    City of Hope Medical Center, Duarte, California

    Locations

    2 in total

    Run by

    City of Hope Medical Center

    See if you can join NCT06731894 on ClinicalTrials.gov

16. International CIPN Assessment and Validation Study

    This is an observational study of chemotherapy-induced peripheral neurotoxicity (CIPN) patients to be investigated prospectively in order to assess responsiveness of a set of outcome measures in an international multi-center study.

    Stage

    Not phased

    Ages

    18 and older

    Site

    "Saint Andrew's" State General Hospital, Pátrai,

    Locations

    30 in total

    Run by

    University of Milano Bicocca

    See if you can join NCT04633655 on ClinicalTrials.gov