Cerebral Palsy Clinical Trials

39 studies are recruiting for cerebral palsy in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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New York, New York 4 Bethesda, Maryland 3 Chicago, Illinois 3 Los Angeles, California 3 Pittsburgh, Pennsylvania 3

Studies now recruiting

  1. Paired Non-invasive VNS in Adolescent Cerebral Palsy Rehabilitation

    This is an open-label safety and feasibility trial evaluating the use of paired non-invasive vagus nerve stimulation (VNS) and upper extremity (UE) rehabilitation in the motor impairment reduction of adolescent patients with spastic cerebral palsy.

    Stage
    Not phased
    Ages
    12 to 17
    Site
    The Charles Lazarus Children's Abilities Center, New York, New York
    Run by
    Icahn School of Medicine at Mount Sinai

    See if you can join NCT07394608 on ClinicalTrials.gov

  2. Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders

    Background: People with cerebral palsy, spina bifida, muscular dystrophy, or spinal cord injury often have muscle weakness and problems controlling how their legs move. This can affect how they walk. The NIH has designed a robotic device (exoskeleton) that can be worn on the legs while walking. The…

    Stage
    Not phased
    Ages
    3 to 17
    Site
    National Institutes of Health Clinical Center, Bethesda, Maryland
    Run by
    National Institutes of Health Clinical Center (CC)

    See if you can join NCT05726591 on ClinicalTrials.gov

  3. Repetitive Transcranial Magnetic Stimulation on Motor Function and Meta-Plasticity in Cerebral Palsy: TMS-EEG Study

    This project examines the use of repetitive transcranial magnetic stimulation (rTMS) as a therapeutic approach to improve motor function in children with cerebral palsy (CP). By applying 6-Hz primed low and high-frequency rTMS and measuring brain responses through TMS-EEG, the study aims to enhance…

    Stage
    Not phased
    Ages
    6 to 20
    Site
    Cook Children's Hospital, Fort Worth, Texas
    Run by
    Cook Children's Health Care System

    See if you can join NCT07567053 on ClinicalTrials.gov

  4. Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for CP

    This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Cerebral Palsy

    Stage
    Phase 1
    Ages
    Any age
    Site
    Prodromos Stem Cell Institute, Naples, Florida
    Locations
    2 in total
    Run by
    The Foundation for Orthopaedics and Regenerative Medicine

    See if you can join NCT05018819 on ClinicalTrials.gov

  5. Safety of Cultured Umbilical or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for CP

    This trial will study the safety and efficacy of intravenous infusion of cultured umbilical or placental derived mesenchymal stem cells for the treatment of Cerebral Palsy

    Stage
    Phase 1
    Ages
    Any age
    Site
    Prodromos Stem Cell Institute, Naples, Florida
    Locations
    2 in total
    Run by
    The Foundation for Orthopaedics and Regenerative Medicine

    See if you can join NCT05018871 on ClinicalTrials.gov

  6. Implementation of Therapy Together

    The goal of this clinical trial is to learn about the implementation of Therapy Together, a pediatric constraint-induced movement therapy program in young children with unilateral cerebral palsy. The main question[s] it aims to answer are: * Is the Therapy Together program effective in improving ha…

    Stage
    Not phased
    Ages
    0 to 5
    Site
    Scottish Rite for Children, Frisco, Texas
    Run by
    Texas Scottish Rite Hospital for Children

    See if you can join NCT06040619 on ClinicalTrials.gov

  7. Chronic Postsurgical Pain

    The study purpose is to document the typical trajectory of perioperative pain experience in Cerebral Palsy (CP) and to identify important predictive factors for the development of chronic postsurgical pain. The main aims of the investigators are to: 1. Quantify the trajectory of pain and opioid use…

    Stage
    Not phased
    Ages
    5 to 17
    Site
    Nemour's Children's Hospital, Wilmington, Delaware
    Locations
    2 in total
    Run by
    Chantel Burkitt

    See if you can join NCT05764681 on ClinicalTrials.gov

  8. Short-term Spinal Stimulation Effects in Cerebral Palsy

    This research study will examine the acute effects of non-invasive spinal stimulation on spasticity and walking in individuals with cerebral palsy. The hypothesis is that walking with spinal stimulation will lead to greater reductions in spasticity than walking without spinal stimulation. Additiona…

    Stage
    Not phased
    Ages
    4 to 65
    Site
    University of Washington, Seattle, Washington
    Run by
    University of Washington

    See if you can join NCT07826494 on ClinicalTrials.gov

  9. Clinical Orthopaedic Data Bank (Acute and Chronic)

    Data involving orthopaedic conditions and rehabilitation aspects of musculoskeletal and neuromuscular disorders will be collected and stored as part of the normal clinical care of patients seen in the University of Florida (UF) and Shands Orthopaedics and Sports Medicine Institute.

    Stage
    Not phased
    Ages
    Any age
    Site
    UF&Shands Orthopaedics and Sports Medicine Institute, Gainesville, Florida
    Run by
    University of Florida

    See if you can join NCT00411060 on ClinicalTrials.gov

  10. Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions

    This study will assess the benefits of using mobile health system designed for individuals with chronic and complex health conditions (such as those with Spinal Cord Injury,Cerebral Palsy, Spina Bifida, and Traumatic Brain Injury) to improve their wellness and self-management skills compared to tho…

    Stage
    Not phased
    Ages
    12 and older
    Site
    University of Pittsburgh, Pittsburgh, Pennsylvania
    Run by
    University of Pittsburgh

    See if you can join NCT02592291 on ClinicalTrials.gov

  11. Training Upper Limbs of Neurodiverse Children by Connecting Brain Activities to a Virtual Reality Based Game

    This study is testing ways to help children with cerebral palsy (CP) improve how their hands work. Investigators want to see if brain activity using a virtual reality (VR) program can make their hands work better. The program is called Hand and Bimanual Intensive Therapy Virtual Reality (HABIT-VR).…

    Stage
    Not phased
    Ages
    6 to 17
    Site
    University of Nebraska Medical Center, Munroe-Meyer Institute, Omaha, Nebraska
    Run by
    University of Nebraska

    See if you can join NCT06818877 on ClinicalTrials.gov

  12. Cerebral Palsy and the Study of Brain Activity During Motor Tasks

    Background: - Two ways to study the brain while people are moving are near-infrared spectroscopy (NIRS) and electroencephalography (EEG). NIRS uses light to look at blood flow in the brain when it is active. EEG records electrical activity in the brain. Both have been used safely for many years, ev…

    Stage
    Not phased
    Ages
    5 to 100
    Site
    National Institutes of Health Clinical Center, Bethesda, Maryland
    Run by
    National Institutes of Health Clinical Center (CC)

    See if you can join NCT01829724 on ClinicalTrials.gov

  13. Dorsal Root Electrical Stimulation in Children With Cerebral Palsy

    The goal of this clinical trial is to evaluate whether dorsal root electrical stimulation could reduce spasticity in children with cerebral palsy (CP).

    Stage
    Not phased
    Ages
    3 to 14
    Site
    UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania
    Run by
    Martin Piazza

    See if you can join NCT07715006 on ClinicalTrials.gov

  14. Robot-assisted Training in Children With CP

    Cerebral palsy (CP) is the most common physical disability in early childhood causing serious motor and sensory impairments. Effective interventions for the recovery of motor functions are of profound significance to children with CP, their families, caregivers, and health professionals. Robot-assi…

    Stage
    Not phased
    Ages
    6 to 18
    Site
    Cook Children's Medical Center, Fort Worth, Texas
    Run by
    Cook Children's Health Care System

    See if you can join NCT06450158 on ClinicalTrials.gov

  15. Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy

    The investigators hope to use MRI biomarkers to identify and characterize sensorimotor network disruption patterns associated with chronic pain and sensory deficits in CP. Investigators will use existing information in the medical record as well as subjective reports from interview, physical exam d…

    Stage
    Not phased
    Ages
    8 and older
    Site
    F.M. Kirby Center, Baltimore, Maryland
    Locations
    4 in total
    Run by
    Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

    See if you can join NCT05197946 on ClinicalTrials.gov

  16. Investigating New Methods to Study Movement in Children and Young Adults With Movement Disorders.

    Background: Cerebral palsy (CP) is the most common motor disorder that affects children. People with CP have weak muscles; they may have trouble controlling the movements of their arms and legs. Researchers have been developing braces called robotic exoskeletons for people with CP. These devices ca…

    Stage
    Not phased
    Ages
    5 to 25
    Site
    National Institutes of Health Clinical Center, Bethesda, Maryland
    Run by
    National Institutes of Health Clinical Center (CC)

    See if you can join NCT06498596 on ClinicalTrials.gov

  17. Gait Adaptation and Biofeedback for Cerebral Palsy

    This research aims to evaluate walking function in children with cerebral palsy (CP). The researchers want to understand how children with CP adapt and learn new ways of moving. They have previously found that measuring how a person controls their muscles is important for assessing walking ability …

    Stage
    Not phased
    Ages
    7 to 18
    Site
    Gillette Children's, Saint Paul, Minnesota
    Run by
    University of Washington

    See if you can join NCT05899153 on ClinicalTrials.gov

  18. Smart AFO and 5-Azacitidine to Enhance Mobility in Children With Cerebral Palsy

    This is an intervention study to investigate the impact of a smart ankle-foot orthosis (AFO) on mobility outcomes in children with Cerebral Palsy. Participants will complete a three phase protocol including 6-weeks of at home training with the smart AFO. Participants will also have the option to pa…

    Stage
    Phase 2
    Ages
    8 to 17
    Site
    Shirley Ryan AbilityLab, Chicago, Illinois
    Run by
    Shirley Ryan AbilityLab

    See if you can join NCT07434492 on ClinicalTrials.gov

  19. tSCS and 5-Azacitidine for Enhanced Motor Outcomes in Cerebral Palsy

    This is an intervention study to investigate the impact of spinal stimulation on mobility outcomes in children with Cerebral Palsy. Participants will complete a 16-week training program with weekly sessions of spinal stimulation and walking or activity-based training. Participants will also have th…

    Stage
    Phase 2
    Ages
    4 to 17
    Site
    Shirley Ryan AbilityLab, Chicago, Illinois
    Run by
    Shirley Ryan AbilityLab

    See if you can join NCT07433023 on ClinicalTrials.gov

  20. Evaluation of Brain MRI Changes in Cerebral Palsy Patients

    Cerebral palsy (CP) is a neurodevelopmental syndrome characterized by sensorimotor impairment that arises during early childhood defined as a static insult to the developing brain. A key part of the definition for CP is a non-progressive brain injury; however, as individuals with CP age, a function…

    Stage
    Not phased
    Ages
    18 to 80
    Site
    Weinberg Family Cerebral Palsy Center, Columbia University, New York, New York
    Run by
    Columbia University

    See if you can join NCT07433647 on ClinicalTrials.gov

  21. Spinal Cord Stimulation for Children With Cerebral Palsy

    The goal of this clinical trial is to help understand spinal cord excitability in children with cerebral palsy compared to neurologically typical children. The main questions it aims to answer are: * What are the mechanisms of spinal circuit hyperexcitability in CP? * Can transcutaneous spinal cord…

    Stage
    Not phased
    Ages
    5 to 17
    Site
    UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania
    Run by
    Martin Piazza

    See if you can join NCT07516067 on ClinicalTrials.gov

  22. Healing Tiny Minds: Rural Recovery Through Virtual and Lived Experience Care

    The goal of this behavioral-interventional study is to learn if the Abecedarian Approach implemented virtually for children ages 0-5 with a history of Hypoxic Ischaemic Encephalopathy (HIE) and/or premature birth produces the same effects as when administered at in-person facilities.

    Stage
    Not phased
    Ages
    Up to 5
    Site
    University of Wisconsin Madison, Madison, Wisconsin
    Run by
    University of Wisconsin, Madison

    See if you can join NCT06643598 on ClinicalTrials.gov

  23. WBV and Serial Casting for Children With Cerebral Palsy

    Children with cerebral palsy have increased muscle tone which often results in decreased active and passive movement at the ankle. While many management strategies exist (including passive stretching, WBV, serial casting, Botox, and surgical tendon lengthening), the utilization of WBV in combinatio…

    Stage
    Not phased
    Ages
    3 to 17
    Site
    Nationwide Children's Hospital, Columbus, Ohio
    Run by
    Ben Reader

    See if you can join NCT06693388 on ClinicalTrials.gov

  24. A Multicenter Pediatric Deep Brain Stimulation Registry

    There is limited data on outcomes for children who have undergone deep brain stimulation (DBS) for movement disorders, and individual centers performing this surgery often lack sufficient cases to power research studies adequately. This study aims to develop a multicenter pediatric DBS registry tha…

    Stage
    Not phased
    Ages
    0 to 18
    Site
    Boston Children's Hospital, Boston, Massachusetts
    Run by
    Boston Children's Hospital

    See if you can join NCT06585618 on ClinicalTrials.gov

  25. Effects of Treadmill Training and Whole-body Vibration in Children With Cerebral Palsy

    Whole-body vibration (WBV) and treadmill training (TT) are commonly-utilized rehabilitation interventions for children with neuromotor disorders. WBV has been shown in the literature to positively affect gait and lower body spasticity in this population. However, the effects of a single session of …

    Stage
    Not phased
    Ages
    6 to 17
    Site
    Georgia State University, Atlanta, Georgia
    Run by
    Georgia State University

    See if you can join NCT04630392 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.