Biliary Tract Cancer Clinical Trials in Pittsburgh, Pennsylvania

5 studies are recruiting for biliary tract cancer in Pittsburgh, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Phase 1 Study of LNCB74 in Advanced Solid Tumors

   This is an open-label, phase 1, dose escalation and dose expansion study to determine safety and tolerability, and to determine the maximum tolerated dose and / or recommended phase 2 dose of LNCB74 in participants with advanced solid tumors.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   UPMC, Pittsburgh, Pennsylvania

   Locations

   14 in total

   Run by

   NextCure, Inc.

   See if you can join NCT06774963 on ClinicalTrials.gov

2. A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

   The purpose of this study is to measure the efficacy and safety of rilvegostomig with gemcitabine plus cisplatin vs. durvalumab with gemcitabine plus cisplatin as first line treatment for patients with advanced BTC.

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Research Site, Pittsburgh, Pennsylvania

   Locations

   177 in total

   Run by

   AstraZeneca

   See if you can join NCT07221253 on ClinicalTrials.gov

3. Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

   The purpose of this study is to measure the efficacy and safety of T-DXd with rilvegostomig or T-DXd monotherapy compared with gemcitabine plus cisplatin and durvalumab in patients with advanced treatment naïve HER2-expressing BTC.

   Stage

   Phase 3

   Ages

   18 to 99

   Site

   Research Site, Pittsburgh, Pennsylvania

   Locations

   269 in total

   Run by

   AstraZeneca

   See if you can join NCT06467357 on ClinicalTrials.gov

4. Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

   The purpose of this study is to assess the efficacy and safety of RP2 in combination with atezolizumab plus bevacizumab (Cohorts 1a and 1b) and RP2 monotherapy (Cohort 2) in the as second line treatment in patients with locally advanced unresectable, recurrent, and/or metastatic HCC and in combinat…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania

   Locations

   12 in total

   Run by

   Replimune, Inc.

   See if you can join NCT05733598 on ClinicalTrials.gov

5. Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery

   This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery. This project is considered "Research" and participation is voluntary. Upon enrollment in this study, the r…

   Stage

   Not phased

   Ages

   18 to 89

   Site

   AHN West Penn Hospital, Pittsburgh, Pennsylvania

   Run by

   Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

   See if you can join NCT06731998 on ClinicalTrials.gov