Autoimmune Diseases Clinical Trials

18 studies are recruiting for autoimmune diseases in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

By city

Studies now recruiting

1. Deciphering the Genetic Architecture of Autoimmune Diseases

   Background: Autoimmune diseases can be caused by genes people inherit from their parents. The gene changes that cause these diseases have been well studied in people with European and Asian ancestors. But some diseases behave differently in people who are native to North and South America. Research…

   Stage

   Not phased

   Ages

   18 to 115

   Site

   Amazon Rainforest, Lima,

   Locations

   2 in total

   Run by

   National Human Genome Research Institute (NHGRI)

   See if you can join NCT06948110 on ClinicalTrials.gov

2. METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)

   The study is a randomized, double-blind, parallel-group clinical trial to examine the effects of 24 weeks of oral AMX0035 (sodium phenylbutyrate + taurursodiol) versus placebo in 60 adults with Type 1 Diabetes (T1D) (n=30 per arm). Enrollment will be distributed equally between the University of Wa…

   Stage

   Phase 2

   Ages

   18 to 69

   Site

   University of Washington Medicine Diabetes Institute (UWMDI), Seattle, Washington

   Locations

   2 in total

   Run by

   University of Washington

   See if you can join NCT07699380 on ClinicalTrials.gov

3. A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

   This study is First In Human study for Encapsulated Porcine Islet Cells for Xenotransplantation (OPF-310). The purpose of this study to assess the safety, tolerability, and efficacy of OPF-310 transplantation and to define the recommended Phase 2 dose (RP2D) in adult subjects with unstable Type 1 D…

   Stage

   Phase 1

   Ages

   35 to 70

   Site

   University of Illinois Hospital & Health Sciences System, Chicago, Illinois

   Run by

   Otsuka Pharmaceutical Factory, Inc.

   See if you can join NCT06575426 on ClinicalTrials.gov

4. Music-4-MS to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study

   Multiple sclerosis (MS) rates in the U.S. have nearly doubled over the past decade, making it a leading cause of nontraumatic functional impairment in young adults and significantly affecting cognitive function in up to 70% of people with MS. While traditional cognitive rehabilitation methods are l…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   University of Texas at Austin, Austin, Texas

   Run by

   University of Texas at Austin

   See if you can join NCT07759115 on ClinicalTrials.gov

5. A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

   This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and other indications.

   Stage

   Not phased

   Ages

   Any age

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   142 in total

   Run by

   Center for International Blood and Marrow Transplant Research

   See if you can join NCT01351545 on ClinicalTrials.gov

6. Testimonials and Navigation in Rheumatology

   The overall goal of this study is to determine whether a novel, multi-modal, patient-directed behavioral intervention initiated in rheumatology clinics is an effective approach to improve uptake of updated COVID-19 vaccine.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   3 in total

   Run by

   University of Alabama at Birmingham

   See if you can join NCT06469788 on ClinicalTrials.gov

7. Ovarian Tissue Cryopreservation for Fertility Preservation

   The goal of this observational study is to learn about fertility preservation for pre-pubertal, peri-pubertal, and adult participants that are unable to pursue clinical standard of care fertility preservation such as egg (oocyte) and embryo cryopreservation. In addition, this study will provide res…

   Stage

   Not phased

   Ages

   Up to 39

   Site

   Magee-Womens Hospital, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT05875155 on ClinicalTrials.gov

8. A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

   A Phase 1 dose-escalation study designed to evaluate the safety, tolerability, and preliminary efficacy of anito-cel in subjects with generalized myasthenia gravis (GMG). Anitocabtagene autoleucel (anito-cel) is a BCMA-directed CAR-T cell therapy.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   UCLA Medical Center, Los Angeles, California

   Locations

   13 in total

   Run by

   Arcellx, Inc.

   See if you can join NCT06626919 on ClinicalTrials.gov

9. Biologics And Clinical Immunology Cohort at Sinai

   The study team plans to establish a bioregistry of patients receiving biologic therapy as part of their standard treatment at the Mount Sinai Therapeutic Infusion Center and affiliated practices. The study team will to apply state-of-the-art approaches to assessing and predicting immunological and …

   Stage

   Not phased

   Ages

   12 and older

   Site

   Mount Sinai, New York, New York

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT04784364 on ClinicalTrials.gov

10. Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

    The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related neuroinflammatory conditions. Participants in the United States aged 2 years…

    Stage

    Not phased

    Ages

    2 and older

    Site

    Brain Inflammation Collaborative, Delafield, Wisconsin

    Run by

    Brain Inflammation Collaborative

    See if you can join NCT04806620 on ClinicalTrials.gov

11. Maternal Autoimmune Disease Research Alliance (MADRA) Registry

    This multi-site registry, centered at Duke University, will enroll pregnant women with autoimmune and rheumatologic diseases. The main goal of MADRA is to identify ways to improve the health of women with rheumatic diseases and their babies during pregnancy. Prior studies demonstrate the importance…

    Stage

    Not phased

    Ages

    Any age

    Site

    Duke University, Durham, North Carolina

    Run by

    Duke University

    See if you can join NCT03276923 on ClinicalTrials.gov

12. Use of Acthar Gel Single-Dose Pre-Filled SelfJectTM Injector in Patients With Moderate-Severe Keratitis and Autoimmune Disease

    Single-site, open label pilot study of 20 autoimmune patients diagnosed with dry eye demonstrating via the proparacaine challenge some peripheral corneal pain component. At least 16 patients will receive and complete 12 weeks of 80 units of Acthar Gel to be injected subcutaneously twice weekly via …

    Stage

    Phase 4

    Ages

    18 to 85

    Site

    Toyos Clinic, Nashville, Tennessee

    Run by

    Toyos Clinic

    See if you can join NCT06964269 on ClinicalTrials.gov

13. X-linked Moesin Associated Immunodeficiency

    Moesin deficiency was initially described in 7 male participants aged 4 to 69 years and is characterized by lymphopenia of the 3 lineages and moderate neutropenia. Genetically, 6 out of 7 participants had the same missense mutation in the moesin gene located on the X chromosome. The 7th patient has…

    Stage

    Not phased

    Ages

    4 to 80

    Site

    Hôpital Necker, Paris, PARIS

    Locations

    10 in total

    Run by

    Institut National de la Santé Et de la Recherche Médicale, France

    See if you can join NCT06278337 on ClinicalTrials.gov

14. Rheumatology Diet Study

    This study aims to collect information on rheumatology patients' dietary habits, autoimmune disease activity, dietary changes, disease symptom improvements, and perceptions on their dietary habits and how it affects their autoimmune disease. The main objective is to see if rheumatology patients cha…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    UCF Health Clinics, Orlando, Florida

    Run by

    University of Central Florida

    See if you can join NCT06339957 on ClinicalTrials.gov

15. VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems

    Vagal nerve stimulation is a neurosurgical procedure consisting of implantation of an impulse generator battery with leads placed into the vagus nerve in the neck. This procedure was FDA approved for epilepsy in the 1990s and is commonly performed as an outpatient surgery. The mechanism of action i…

    Stage

    Not phased

    Ages

    0 to 60

    Site

    University of Louisville, Louisville, Kentucky

    Locations

    4 in total

    Run by

    University of Louisville

    See if you can join NCT03953768 on ClinicalTrials.gov

16. IMPACT - AndHealth Autoimmune Research Registry

    This is a patient research registry aimed at evaluating the effectiveness of a comprehensive, root-cause medical approach ("AndHealth program") for autoimmune disorders. This approach involves a combination of pharmacological and non-pharmacological therapies offered under the care of a licensed ph…

    Stage

    Not phased

    Ages

    18 to 70

    Site

    AndHealth, Columbus, Ohio

    Run by

    AndHealth

    See if you can join NCT05883371 on ClinicalTrials.gov

17. Collection and Distribution of Biospecimens for Novel Research Uses

    iSpecimen aims to create a clinical partner network of hospitals, laboratories, academic institutions, and other healthcare organizations ("institutions") capable of providing researchers and educators ("researchers") with annotated biospecimens for use in biomarker discovery and validation; diagno…

    Stage

    Not phased

    Ages

    0 to 89

    Site

    iSpecimen, Huntsville, Alabama

    Locations

    2 in total

    Run by

    iSpecimen Inc

    See if you can join NCT03848962 on ClinicalTrials.gov

18. Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions

    This multi-arm, multi-site study investigates the safety, tolerability, and efficacy of stem cell therapy for the treatment of various acute and chronic conditions. Clinically observed initial findings and an extensive body of research indicate regenerative treatments are both safe and effective fo…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Southern California Hospital at Culver City / Southern California Hospital at Hollywood / Multiple US-based Sub-Investigator Sites, Culver City, California

    Run by

    Thomas Advanced Medical LLC

    See if you can join NCT04684602 on ClinicalTrials.gov