Attention Deficit Hyperactivity Disorder Clinical Trials

21 studies are recruiting for attention deficit hyperactivity disorder in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Developing Brain, Impulsivity and Compulsivity

   Background: Impulsivity is acting 'without thinking.' Compulsivity is being overly inflexible. People vary in how impulsive or compulsive they are. Extreme versions of these behaviors play a role in mental disorders. Researchers want to study changes in the brain to learn more about these behaviors…

   Stage

   Not phased

   Ages

   6 to 80

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Mental Health (NIMH)

   See if you can join NCT04631042 on ClinicalTrials.gov

2. A Study to Test the Effects of Centanafadine in Adults With Attention-deficit/Hyperactivity Disorder and Emotional Dysregulation

   The primary purpose of this study is to evaluate the efficacy of centanafadine once daily (QD) extended-release (XR) capsules in adults with attention-deficit/hyperactivity disorder (ADHD) and emotional dysregulation (ED).

   Stage

   Phase 3

   Ages

   18 to 65

   Site

   Nola Research Works, New Orleans, Louisiana

   Locations

   16 in total

   Run by

   Otsuka Pharmaceutical Development & Commercialization, Inc.

   See if you can join NCT07759154 on ClinicalTrials.gov

3. Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD

   This study will evaluate the efficacy and safety of SPN-812 (viloxazine extended release) in children 4 to 5 years of age with ADHD.

   Stage

   Phase 4

   Ages

   4 to 5

   Site

   The Center for Clinical Trials, Inc., Saraland, Alabama

   Locations

   47 in total

   Run by

   Supernus Pharmaceuticals, Inc.

   See if you can join NCT04781140 on ClinicalTrials.gov

4. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

   The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK…

   Stage

   Not phased

   Ages

   0 to 20

   Site

   Lucile Packard Children's Hospital, Palo Alto, California

   Locations

   52 in total

   Run by

   Duke University

   See if you can join NCT04278404 on ClinicalTrials.gov

5. Trigeminal Nerve Stimulation for Children With Prenatal Alcohol Exposure

   This is an open-label trial of trigeminal nerve stimulation (TNS) for children aged 8-12 years with attention deficit hyperactivity disorder (ADHD) putatively due to prenatal alcohol exposure (PAE). TNS has been successful in treating pediatric ADHD generally and it is US Food and Drug Administrati…

   Stage

   Not phased

   Ages

   8 to 12

   Site

   University of California Los Angeles Semel Institute Division of Child & Adolescent Psychiatry, Los Angeles, California

   Run by

   University of California, Los Angeles

   See if you can join NCT06847165 on ClinicalTrials.gov

6. Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial

   Background: Children with attention deficit hyperactivity disorder (ADHD) often have cognitive problems. It may be hard for them to control their behaviors, concentrate for long periods, or make decisions. This can affect their education, friendships, and daily life. Virtual reality-based games may…

   Stage

   Phase 1

   Ages

   8 to 16

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Mental Health (NIMH)

   See if you can join NCT05608434 on ClinicalTrials.gov

7. Enhancing Team Effectiveness for a Collaborative School-based Intervention for ADHD

   The proposed project aims to integrate team-based implementation strategies with an established school-based intervention for children with ADHD, the Collaborative Life Skills Program (CLS), to enhance its implementation and optimize its effectiveness. The investigators will tailor three empiricall…

   Stage

   Not phased

   Ages

   7 to 11

   Site

   IN STEP Children's Mental Health Center, San Diego, California

   Run by

   University of California, San Diego

   See if you can join NCT06180681 on ClinicalTrials.gov

8. Neurocognitive Effects of Non-Invasive Near-Infrared Light Stimulation

   Inattentiveness and impulsivity in healthy adults and individuals with attention deficit hyperactivity disorder (ADHD) diminish these individuals' quality of life. Cortical hypometabolism has been hypothesized to contribute to inattentiveness in ADHD. Transcranial photobiomodulation (tPBM) is a saf…

   Stage

   Not phased

   Ages

   18 and older

   Site

   The University of Texas at Austin, Austin, Texas

   Run by

   Francisco Gonzalez-Lima, PhD

   See if you can join NCT05802680 on ClinicalTrials.gov

9. Effects of Transcranial Photobiomodulation in ADHD

   The investigators have previously shown that non-invasive methods of brain stimulation such as the administration of transcranial infrared light to the prefrontal cortex (PFC) can result in improvements to cognition and emotion as well as brain oxygenation. This method is called transcranial photob…

   Stage

   Not phased

   Ages

   18 to 44

   Site

   The University of Texas at Austin, Austin, Texas

   Run by

   Francisco Gonzalez-Lima, PhD

   See if you can join NCT07203092 on ClinicalTrials.gov

10. Motor Attention Training for Attention Deficit Hyperactivity Disorder (ADHD)

    The investigators will perform a feasibility/pilot trial of two non-pharmacological interventions for ADHD in college students.

    Stage

    Not phased

    Ages

    18 to 23

    Site

    University of Wisconsin-Madison, Waisman Center, Madison, Wisconsin

    Run by

    University of Wisconsin, Madison

    See if you can join NCT02688959 on ClinicalTrials.gov

11. The Effects of Cannabigerol on Attention-Deficit/Hyperactivity Disorder

    The goal of this clinical trial is to evaluate the effects of Cannabigerol (CBG) on indicators of Attention-Deficit/Hyperactivity Disorder (ADHD) in a sample of participants indicating/reporting symptoms associated with ADHD. The main question it aims to answer is: Does CBG reduce ADHD-related indi…

    Stage

    Phase 2

    Ages

    18 to 55

    Site

    University of Arkansas, Fayetteville, Arkansas

    Run by

    University of Arkansas, Fayetteville

    See if you can join NCT06115603 on ClinicalTrials.gov

12. An Open-Label Treatment With Randomization Observation, Investigator-Initiated Study, on the Duration and Efficacy of Jornay PM (Methylphenidate Hydrochloride Extended-Release Capsules) on Adult ADHD Symptoms and Executive Function and Emotional Regulation Throughout the Day Into Early Evening

    The goal of this study is to extend the efficacy evidence of sustained release methylphenidate compound (JornayPM) in adults with Attention-deficit/hyperactivity disorder (ADHD). JornayPM has recently been approved for treatment of patients 6 years and older with ADHD; the release mechanism is uniq…

    Stage

    Phase 4

    Ages

    18 to 60

    Site

    NYU Langone Health, New York, New York

    Run by

    NYU Langone Health

    See if you can join NCT06577779 on ClinicalTrials.gov

13. A Pilot Study of a Remote ADHD Monitoring Program

    RAMP is a pilot study examining the use of an Attention-Deficit/Hyperactivity Disorder (ADHD) Monitoring Program during the early stages of treating ADHD in children living in rural settings. This trial will enroll 36 caregiver/infant dyads across 2 sites and will evaluate feasibility endpoints rat…

    Stage

    Not phased

    Ages

    5 to 11

    Site

    University of Mississippi Medical Center, Jackson, Mississippi

    Locations

    2 in total

    Run by

    IDeA States Pediatric Clinical Trials Network

    See if you can join NCT06743425 on ClinicalTrials.gov

14. R61/33 - VR Study Phase 4

    The goal of this larger parallel group randomized trial is to test the impact of a virtual reality program for improving the ability of emerging adults (age 18-25) with attention deficit hyperactivity disorder (ADHD) to stay focused while completing homework and studying. This study compares the im…

    Stage

    Phase 4

    Ages

    18 to 25

    Site

    Louisiana State University, Baton Rouge, Louisiana

    Locations

    2 in total

    Run by

    Rutgers, The State University of New Jersey

    See if you can join NCT07169760 on ClinicalTrials.gov

15. ADHD PreSMA Response Inhibition Therapy

    ADHD children have abnormal inhibitory control, meaning they have trouble stopping themselves from doing something they should not do. This ability to control involves an area in the brain called the pre-supplementary motor area (pre-SMA). Scientists have previously shown that the pre-SMA is abnorm…

    Stage

    Not phased

    Ages

    12 to 17

    Site

    Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

    Run by

    Children's Hospital Medical Center, Cincinnati

    See if you can join NCT06325813 on ClinicalTrials.gov

16. Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

    In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have deficits in this cognitive domain.

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT04296604 on ClinicalTrials.gov

17. Project PEAK: Early Intervention for ADHD

    Parent education is an effective and relatively cost efficient approach for reducing child behavior problems. Research, however, suggests that the effectiveness of parent education is mitigated by parent attendance and parent implementation of intervention strategies. That is, low attendance at par…

    Stage

    Not phased

    Ages

    3 to 5

    Site

    Lehigh University, Bethlehem, Pennsylvania

    Run by

    Lehigh University

    See if you can join NCT04627415 on ClinicalTrials.gov

18. Focus Groups in Ethnically and Racially Diverse Families

    Focus groups to identify treatment needs and barriers to participation in the planned multinutrient study among racially and ethnically diverse (Black and Hispanic) communities.

    Stage

    Not phased

    Ages

    18 to 80

    Site

    Oregon Health & Science University, Portland, Oregon

    Run by

    Oregon Health and Science University

    See if you can join NCT05930886 on ClinicalTrials.gov

19. Stimulant Effects on Disruptive Behavior

    The goal of this study is to determine the effects of stimulant medication on disruptive behavior, function, preference and choice; however, it is primarily methodological and will add to current research by establishing an effective evaluation of the impact of stimulant medication on these behavio…

    Stage

    Phase 4

    Ages

    4 to 12

    Site

    University of Iowa Hospitals and Clinics, Iowa City, Iowa

    Run by

    Matthew J O'Brien, PhD, BCBA-D

    See if you can join NCT03420339 on ClinicalTrials.gov

20. Optimizing Research With Diverse Families - Feasibility and Acceptability Study (FAST)

    Evaluate feasibility and acceptability of recruiting Black and Hispanic families for an open label clinical trial of multinutrients while collecting real-time parent-reported child behavior data and collecting at-home biospecimens to explore their potential as biomarkers, in a study of pediatric AD…

    Stage

    Not phased

    Ages

    6 to 17

    Site

    Oregon Health & Science University, Portland, Oregon

    Run by

    Oregon Health and Science University

    See if you can join NCT06133231 on ClinicalTrials.gov

21. A Trial of Dyanavel XR in Treating Co-occurring Fatigue Symptoms in Adults With Attention Deficit Hyperactivity Disorder (ADHD).

    The goal of this clinical trial is to study the impact of Dyanavel on co-occuring fatigue in adults with Attention Deficit/Hyperactivity Disorder. The main question it aims to answer is whether Dyanavel XR leads to a statistically significant reduction in fatigue compared to placebo, as measured by…

    Stage

    Phase 4

    Ages

    18 to 65

    Site

    Rochester Center for Behavioral Medicine, Rochester Hills, Michigan

    Run by

    Rochester Center for Behavioral Medicine

    See if you can join NCT06248229 on ClinicalTrials.gov