Anxiety Disorders Clinical Trials

35 studies are recruiting for anxiety disorders in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders

   Study Description: This study examines relations between neurocognitive and clinical features of pediatric anxiety disorders. The study uses neuro-cognitive tasks, functional magnetic resonance imaging (fMRI), as well as magneto- and electro-encephalography (M/EEG). Patients will be studied over on…

   Stage

   Phase 2

   Ages

   8 to 65

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Locations

   2 in total

   Run by

   National Institute of Mental Health (NIMH)

   See if you can join NCT00018057 on ClinicalTrials.gov

2. Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety: R33 Phase

   Anxiety is chronic, debilitating, and the most common mental health problem across development, costing the U.S. over $42 billion annually. This phased innovation grant will test a symptom-personalized cognitive bias modification for interpretation bias (CBM-I) as a mechanistic intervention to redu…

   Stage

   Not phased

   Ages

   10 to 17

   Site

   University of Denver, Denver, Colorado

   Run by

   University of Denver

   See if you can join NCT07818876 on ClinicalTrials.gov

3. MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients

   Pregnant and postpartum patients hospitalized for medical complications experience high rates of depression, anxiety, and trauma-related symptoms, yet access to timely psychiatric care during obstetric hospitalization is limited. Project MOCHA integrates early mental health screening, trauma-inform…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana

   Run by

   Indiana University

   See if you can join NCT07540585 on ClinicalTrials.gov

4. Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

   Background: Anxiety disorders are becoming more common among children and teenagers. Anxiety can lead to long-term physical and mental problems, such as depression. Treatments for anxiety disorders include medications as well as cognitive behavioral therapy (CBT); CBT is a form of talking therapy. …

   Stage

   Phase 2

   Ages

   8 to 17

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Mental Health (NIMH)

   See if you can join NCT06595953 on ClinicalTrials.gov

5. Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

   The purpose of this protocol is to allow for the careful screening of patients and healthy volunteers for participation in research protocols in the Experimental Therapeutics and Pathophysiology Lab (ETPB) at the National Institute of Mental Health (NIMH) and for the collection of natural history d…

   Stage

   Not phased

   Ages

   3 to 99

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Mental Health (NIMH)

   See if you can join NCT00024635 on ClinicalTrials.gov

6. Creating Health Course Study for People With Rheumatological Conditions and Mood Disorders

   The goal of this project is to critically evaluate the effectiveness of an online health program designed to improve diet and self-care in patients with rheumatological conditions, including rheumatoid arthritis (RA), Sjogren's syndrome (SS), systemic lupus erythematosus (SLE), mixed connective tis…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   Univeristy of Iowa, Iowa City, Iowa

   Run by

   Terry L. Wahls

   See if you can join NCT07180537 on ClinicalTrials.gov

7. Mindful Self-Compassion for Anxiety Disorders and Depression

   The study will compare 8-week Mindful Self-Compassion training, compared to a control group that does not receive the intervention, on anxiety and depression symptom severity in patients with diagnosed anxiety disorders (generalized anxiety disorder, social anxiety disorder, and panic disorder) or …

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Georgetown University Medical Center, Washington D.C., District of Columbia

   Run by

   Georgetown University

   See if you can join NCT05671419 on ClinicalTrials.gov

8. Enhancing Engagement by Integrating Goals and Concerns That Matter to Patients

   The goal of this clinical trial is to learn if adding patients' goals and concerns to measurement-based collaborative care can tailor care and provide a more holistic view of treatment, thereby improving engagement in care among adult patients receiving collaborative care. The main questions it aim…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   Dartmouth Hitchcock Concord Family Medicine, Concord, New Hampshire

   Locations

   6 in total

   Run by

   Dartmouth-Hitchcock Medical Center

   See if you can join NCT06898593 on ClinicalTrials.gov

9. Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders

   This study is intended to help develop new MRI imaging techniques for studying mood and anxiety disorders. Researchers believe that depression and anxiety disorders may cause structural and functional changes in the brain. This study will optimize the way MRI scans are collected to look at brain st…

   Stage

   Not phased

   Ages

   18 to 65

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Mental Health (NIMH)

   See if you can join NCT00397111 on ClinicalTrials.gov

10. Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness

    This research study aims to develop a brief group-based treatment called Resilience Training for Teens, then to test how well it protects high school students with mild symptoms of depression, anxiety, or having unusual feelings from developing mental illnesses.

    Stage

    Not phased

    Ages

    14 to 19

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT05962879 on ClinicalTrials.gov

11. Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function

    Growing up in a lower-income family robustly predicts worse mental health in adolescence and early adulthood. How does variability in family income "get under the skin" of the developing child and via what mechanisms does it increase risk for mental illness? Moreover, could supplements to family in…

    Stage

    Not phased

    Ages

    10 to 18

    Site

    Northwestern University, Evanston, Illinois

    Run by

    Northwestern University

    See if you can join NCT07641244 on ClinicalTrials.gov

12. RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty

    It is envisioned that multipronged benefits from this pilot work for the UPMC ISD and its members. It is expected the RxWell platform to provide the following benefits: expansion of the use of RxWell to all UPMC ISD members providing peri-operative mood management with advantage of improved peri-op…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    UPMC East, Monroeville, Pennsylvania

    Locations

    3 in total

    Run by

    University of Pittsburgh

    See if you can join NCT05658796 on ClinicalTrials.gov

13. Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders

    A 24-week, patient- and rater-blinded, two-arm, parallel-group controlled, and multi-centre randomized clinical trial (RCT) to establish the benefits of pharmacogenetics-informed pharmacotherapy versus dosing as usual (DAU) in psychiatric patients suffering from mood, anxiety, or psychotic disorder…

    Stage

    Not phased

    Ages

    16 to 70

    Site

    University Hospital Bonn, Department of Psychiatry and Psychotherapy, Bonn,

    Locations

    9 in total

    Run by

    Parnassia Groep

    See if you can join NCT05656469 on ClinicalTrials.gov

14. A Preventive Behavioral Intervention for Young Adults With Psychotic Experiences

    This is a randomized controlled trial testing the efficacy of Resilience Training in college students with elevated transdiagnostic risk for developing a serious mental illness.

    Stage

    Not phased

    Ages

    18 to 30

    Site

    Massachusetts General Hospital, Charlestown, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT06929442 on ClinicalTrials.gov

15. Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method

    The study will compare the delivery of an 8-week Mindful Self-Compassion training, in-person against video-conference, on anxiety and depression symptom severity in patients with diagnosed anxiety disorders (generalized anxiety disorder, social anxiety disorder, and panic disorder) or major depress…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Georgetown University Medical Center, Washington D.C., District of Columbia

    Run by

    Georgetown University

    See if you can join NCT07028216 on ClinicalTrials.gov

16. Pilot Effectiveness Trial of an ACT Self-help Workbook Tailored Specifically for Prisons

    The goal of this research study is to adapt an ACT-self-help workbook to the prison setting and determine the feasibility acceptability, and effectiveness of this workbook. Participants can expect to be in the study for 13 weeks.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Wisconsin, Madison, Wisconsin

    Run by

    University of Wisconsin, Madison

    See if you can join NCT06162624 on ClinicalTrials.gov

17. DINO RCT - Treating Anxiety in Children With Autism

    Anxiety is prevalent in young children, under 7 years of age, with autism. Yet, few studies have examined anxiety interventions for this age range, and only one anxiety treatment study has included young children with cognitive and language delays. Anxiety treatment models utilizing cognitive-behav…

    Stage

    Not phased

    Ages

    4 to 6

    Site

    Kennedy Krieger Institute, Baltimore, Maryland

    Run by

    Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

    See if you can join NCT06066983 on ClinicalTrials.gov

18. Biomarkers for Exercise

    The overarching objective is to examine the brain-based biological mechanistic pathway by which exercise exerts anxiolytic effects. The investigators will measure brain-derived markers of mitochondrial metabolism (acetyl-L-carnitine [LAC]) and inflammation (interleukin-6 [IL-6]) using innovative te…

    Stage

    Not phased

    Ages

    18 to 50

    Site

    NYU Langone Health, New York, New York

    Run by

    NYU Langone Health

    See if you can join NCT07340281 on ClinicalTrials.gov

19. Modulating Anxious Coping

    This is a study to find out if a device that temporarily alters brain activity (repetitive transcranial magnetic stimulation, rTMS) might be used to change how people with anxiety or related concerns cope with feared or anxiety-producing situations. The study is recruiting people who recently start…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Medical University of South Carolina, Charleston, South Carolina

    Run by

    Medical University of South Carolina

    See if you can join NCT04824105 on ClinicalTrials.gov

20. Cannabidiol-Assisted Learning for Managing Generalized Anxiety Disorder

    This randomized, double-blind, placebo-controlled clinical trial investigates the use of Food and Drug Administration (FDA)-approved cannabidiol (EPIDIOLEX®) as an adjunct to cognitive behavioral therapy (CBT) in adults with generalized anxiety disorder (GAD). The study aims to evaluate whether can…

    Stage

    Phase 3

    Ages

    18 to 45

    Site

    Wayne State University School of Medicine, Tolan Park Medical Building, Detroit, Michigan

    Run by

    Wayne State University

    See if you can join NCT07123467 on ClinicalTrials.gov

21. Neurostimulation Versus Therapy for Problems With Emotions

    The primary goal of this clinical trial is to evaluate the unique neural and behavioral effects of a one-session training combining emotion regulation skills training, with excitatory repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex (dlPFC). The secondary …

    Stage

    Not phased

    Ages

    18 to 55

    Site

    Duke University Medical Center, Durham, North Carolina

    Run by

    Duke University

    See if you can join NCT05712057 on ClinicalTrials.gov

22. Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety

    The goal of this clinical trial is to compare two different intensive formats of delivering cognitive-behavioral treatment for people with PTSD and anxiety disorders. The main questions it aims to answer are: * Is iTCBT delivered in individual and group formats more effective than TAU in improving …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Michael E. DeBakey VA Medical Center, Houston, Texas

    Run by

    Baylor College of Medicine

    See if you can join NCT05843695 on ClinicalTrials.gov

23. Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth

    Emotional dysregulation in justice-involved youth (JIY) is a condition that significantly impacts young people, their families, and juvenile justice and public health systems. Affecting an estimated 60-70% of detained Attention deficit hyperactivity disorderadolescents, it is a major driver of aggr…

    Stage

    Not phased

    Ages

    12 to 18

    Site

    San Luis Obispo County Juvenile Hall, San Luis Obispo, California

    Run by

    SoundHeal

    See if you can join NCT07364799 on ClinicalTrials.gov

24. Cultural Adaptation of a SSI for Youth Anxiety

    The overarching objective of this protocol is to (1) adapt and (2) disseminate an evidence-based, brief (approximately 30 minute) single session intervention (SSI) to better reflect the cultural and linguistic diversity of Latin, Haitian, and Haitian-American individuals via a fully online platform.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Miami, Miami, Florida

    Run by

    University of Miami

    See if you can join NCT04729504 on ClinicalTrials.gov

25. Expansion and Evaluation of AI-generated Clinical Assessment (AI-COA®) of Depression and Anxiety Severity

    The SEQUOIA-1 study evaluates the effectiveness of Artificial Intelligence (AI) in measuring depression and anxiety severity in adults. Investigators from Deliberate Solutions, Inc. and Baylor College of Medicine are conducting this study to determine whether AI can provide reliable clinical assess…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Baylor College of Medicine, Houston, Texas

    Run by

    Deliberate Solutions Inc.

    See if you can join NCT06923995 on ClinicalTrials.gov