Anorexia Nervosa Clinical Trials

24 studies are recruiting for anorexia nervosa in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

By city

Studies now recruiting

1. Efficacy of Non-invasive Vagus Nerve Stimulation for Treatment of Low Weight Eating Disorders

   This project includes a 4-week randomized trial comparing pre-meal vagal nerve stimulation (taVNS) to pre-meal sham stimulation. The aims will assess if taVNS results in greater satisfaction, greater calorie consumption, less self-reported fullness, decrease in eating disorder symptoms, and less an…

   Stage

   Not phased

   Ages

   14 to 22

   Site

   Department of Psychiatry, Eating and Weight Disorders Program, New York, New York

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT05554172 on ClinicalTrials.gov

2. Identifying Multidimensional Signatures of Gastric Interoception in Functional Dyspepsia

   This study is being conducted to investigate gut-brain communication in individuals with functional dyspepsia and anorexia nervosa. The hope is that what the investigators learn from this study will improve the understanding the conditions better to improve treatments.

   Stage

   Not phased

   Ages

   18 to 65

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT07772167 on ClinicalTrials.gov

3. Neuroscience-informed Treatment to Remotely Target Reward Mechanisms in Post-acute Anorexia Nervosa

   The investigators will recruit individuals with broadly-defined AN (n = 80) who are currently in or have recently participated in higher-level eating disorder treatment (e.g., residential, partial hospitalization/day treatment, intensive outpatient treatment). Interested participants will sign cons…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Virginia Commonwealth University, Richmond, Virginia

   Run by

   Virginia Commonwealth University

   See if you can join NCT05799872 on ClinicalTrials.gov

4. Eating Disorder Dynamic Intervention

   The goal of this study is to develop and test a digital program to help people with eating disorders in their everyday lives. The program uses brief surveys and sensor data collected by smartphones to understand when someone may be at higher risk for behaviors like restricting food, binge eating, o…

   Stage

   Not phased

   Ages

   18 to 70

   Site

   Dartmouth College, Lebanon, New Hampshire

   Run by

   Trustees of Dartmouth College

   See if you can join NCT07600671 on ClinicalTrials.gov

5. Effects of rTMS on Food Choice in Anorexia Nervosa

   This study will examine the impact of high-frequency repetitive transcranial magnetic stimulation on food choice behavior and related neural activity.

   Stage

   Not phased

   Ages

   18 to 35

   Site

   New York State Psychiatric Institute, New York, New York

   Run by

   New York State Psychiatric Institute

   See if you can join NCT05918835 on ClinicalTrials.gov

6. Eating Disorders Genetics Initiative 2

   The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrolling 20,000 new participants with anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), avoidant/restr…

   Stage

   Not phased

   Ages

   12 to 99

   Site

   University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

   Locations

   5 in total

   Run by

   University of North Carolina, Chapel Hill

   See if you can join NCT06594913 on ClinicalTrials.gov

7. Interoceptive Exposure for Adolescents With Low Weight Eating Disorders

   This project includes a parallel group randomized controlled trial comparing two psychological treatments: 1) Exposure-based Family Therapy (IE) vs. 2) Family Based Therapy (FBT) for low weight eating disorders with 12 month follow-up. Primary outcomes are expected body weight and clinical impairme…

   Stage

   Not phased

   Ages

   12 to 18

   Site

   Department of Psychiatry, Eating and Weight Disorders Program, New York, New York

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT05763849 on ClinicalTrials.gov

8. Relapse Prevention and Changing Habits in Anorexia Nervosa

   This study aims to optimize a treatment package for the relapse prevention treatment of AN. In the Preparation Phase, we examined accessibility and feasibility of the treatment package. In the current Optimization Phase, we will identify which components of treatment contribute to positive outcomes…

   Stage

   Not phased

   Ages

   18 to 60

   Site

   New York State Psychiatric Institute, New York, New York

   Run by

   New York State Psychiatric Institute

   See if you can join NCT04810624 on ClinicalTrials.gov

9. Transdermal Estrogen in Women With Anorexia Nervosa

   Randomized, placebo-controlled study investigating the use of physiologic, transdermal estrogen for low bone mass in adult women with anorexia nervosa.

   Stage

   Phase 2

   Ages

   19 to 45

   Site

   University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

   Run by

   Pouneh K. Fazeli, MD

   See if you can join NCT03875378 on ClinicalTrials.gov

10. Targeting Social Function in Anxiety and Eating Disorders

    Social processing and cognition are often altered in patients with eating disorders. The goal of this clinical trial is to assess two different social therapeutic interventions -- one educational, one interactive -- for their effectiveness in improving clinical outcomes in patients with eating diso…

    Stage

    Not phased

    Ages

    18 to 30

    Site

    UT Southwestern Multispecialty Psychiatry Clinic, Dallas, Texas

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT06198023 on ClinicalTrials.gov

11. Avoidance-driven Decision Making and Learning in Anorexia Nervosa and Bulimia Nervosa

    The purpose of this study is to investigate areas of the brain responsible for avoidance learning in adults with eating disorders using brain imaging techniques, computer tasks, and self-report questionnaires and interviews. The investigators will study changes in brain activity using a procedure c…

    Stage

    Not phased

    Ages

    18 to 39

    Site

    UCSD Eating Disorders Treatment and Research Program, La Jolla, California

    Run by

    University of California, San Diego

    See if you can join NCT06566612 on ClinicalTrials.gov

12. Incentive Processing and Learning in Anorexia Nervosa and Bulimia Nervosa

    The purpose of this study is to investigate areas of the brain responsible for 'liking', 'wanting', and learning in adults with eating disorders using brain imaging techniques, computer tasks, a test meal, and self-report questionnaires and interviews. The investigators will study changes in brain …

    Stage

    Not phased

    Ages

    18 to 39

    Site

    UCSD Eating Disorders Treatment and Research Program, La Jolla, California

    Run by

    University of California, San Diego

    See if you can join NCT05056597 on ClinicalTrials.gov

13. Ketogenic Diet and Brain Response in Anorexia Nervosa

    This is a longitudinal study with an open design in weight recovered anorexia nervosa (wrAN) individuals. Healthy controls (HC) will also be assessed. Study participants will be carefully assessed and will have 18F-fluorodeoxyglucose ([18F]FDG) positron emission tomography (PET) scans for assessmen…

    Stage

    Not phased

    Ages

    18 to 45

    Site

    University of California San Diego, San Diego, California

    Run by

    University of California, San Diego

    See if you can join NCT06540703 on ClinicalTrials.gov

14. Developing an Artificial Intelligence (AI) Chatbot for Adolescents and Young Adults With Eating Disorders

    The goal of this study is to develop and refine an artificial intelligence (AI)-powered Exposure Therapy for Eating Disorders chatbot web-app that effectively engages adolescents and young adults and decreases anxiety about weight gain. Participants will use the web-app as a supplemental therapeuti…

    Stage

    Not phased

    Ages

    12 to 26

    Site

    Penn State College of Medicine, Hershey, Pennsylvania

    Run by

    Milton S. Hershey Medical Center

    See if you can join NCT07237607 on ClinicalTrials.gov

15. Adapting Exposure for Adolescent AN

    This pilot study is evaluating Exposure Therapy (Exp-AN) as a virtual treatment for adolescents (ages 14 - 17 years) with anorexia nervosa (AN) recruited from eating disorder clinic waitlists and clinician referrals at the Penn State Milton S. Hershey Medical Center and the University of California…

    Stage

    Not phased

    Ages

    14 to 17

    Site

    Penn State College of Medicine, Hershey, Pennsylvania

    Run by

    Milton S. Hershey Medical Center

    See if you can join NCT07188155 on ClinicalTrials.gov

16. Study of Food Aversion in Patients With Anorexia Nervosa

    This study uses a meal-challenge protocol to assess if patients with anorexia nervosa show a differential metabolism in response to food in comparison to healthy controls. This study determines how heritable and biochemical factors influence food metabolism in anorexia nervosa in order to develop m…

    Stage

    Not phased

    Ages

    18 to 55

    Site

    UC San Diego Altman Clinical and Translational Research Institute, La Jolla, California

    Locations

    2 in total

    Run by

    University of California, San Diego

    See if you can join NCT03100656 on ClinicalTrials.gov

17. Study of Psilocybin for Anorexia in Young Adults

    This is a single site trial of psilocybin therapy for the treatment of refractory Anorexia Nervosa in young adults. The psilocybin therapy will include three preparatory sessions, psilocybin dosing session one (20mg), two integration sessions, psilocybin dosing session two (up to 25mg), and three f…

    Stage

    Phase 2

    Ages

    18 to 25

    Site

    University of California, San Francisco, San Francisco, California

    Locations

    2 in total

    Run by

    Marissa Raymond-Flesch, MD, MPH

    See if you can join NCT06399263 on ClinicalTrials.gov

18. Metabolic Diet for Relapse Prevention in Anorexia Nervosa

    This is an interventional study that will test the safety, tolerability, and efficacy of the Metabolic Diet, which was designed as a treatment for women with anorexia nervosa to remain weight-stable after they have been restored from low weight. Participants will be adult women with anorexia nervos…

    Stage

    Not phased

    Ages

    18 to 40

    Site

    Icahn School of Medicine at Mount Sinai, New York, New York

    Run by

    Icahn School of Medicine at Mount Sinai

    See if you can join NCT05197309 on ClinicalTrials.gov

19. Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder

    Hypothesis: Will the use of tDCS brain modulation in the cerebellum assist in restricted behaviors, social cognition and cognitive flexibility in women with anorexia nervosa in addition to other therapies? Primary Outcomes: 1. To observe the impacts and outcomes of cerebellar transcranial direct cu…

    Stage

    Not phased

    Ages

    15 to 30

    Site

    UT Southwestern Multispecialty Psychiatry Clinic, Dallas, Texas

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT06286930 on ClinicalTrials.gov

20. Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

    The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related neuroinflammatory conditions. Participants in the United States aged 2 years…

    Stage

    Not phased

    Ages

    2 and older

    Site

    Brain Inflammation Collaborative, Delafield, Wisconsin

    Run by

    Brain Inflammation Collaborative

    See if you can join NCT04806620 on ClinicalTrials.gov

21. Interoceptive Mechanisms of Body Image Disturbance in Anorexia Nervosa

    The proposed study utilizes a randomized experimental therapeutics design to test a mechanistic framework linking interoceptive processing and disturbed body image, with the purpose of informing the development of future therapies for body image dissatisfaction in anorexia nervosa (AN). A sample of…

    Stage

    Not phased

    Ages

    13 to 50

    Site

    Laureate Institute for Brain Research, Tulsa, Oklahoma

    Run by

    Laureate Institute for Brain Research, Inc.

    See if you can join NCT06332963 on ClinicalTrials.gov

22. Open vs. Blind Weighing Study In Adolescents and Young Adult With Eating Disorders

    Current treatments for adolescents and young adults (AYAs) with eating disorders (EDs) do not effectively address a central ED symptom - anxiety about weight gain - which contributes to poor outcomes. The proposed study evaluates the feasibility, acceptability, efficacy, and underlying mechanisms o…

    Stage

    Not phased

    Ages

    12 to 24

    Site

    905 W Govener Rd, Hershey, Pennsylvania

    Run by

    Milton S. Hershey Medical Center

    See if you can join NCT06085092 on ClinicalTrials.gov

23. Therapeutic Ketogenic Diet in Anorexia Nervosa

    This study will investigate the effects of therapeutic ketogenic diet (TKD) on eating behavior including drive to restrict, body dissatisfaction, mood and anxiety in individuals with anorexia nervosa who have been weight normalized (body mass index of 17.5 or greater) but continue to struggle with …

    Stage

    Not phased

    Ages

    18 to 45

    Site

    University of California San Diego, San Diego, California

    Run by

    University of California, San Diego

    See if you can join NCT06000774 on ClinicalTrials.gov

24. Confirming the Effectiveness of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa

    With an incidence rate of about 1%, Anorexia Nervosa (AN) is a serious mental disorder associated with high mortality, morbidity, and cost. AN in youth is more responsive to early treatment but becomes highly resistant once it has taken an enduring course. The first-line treatment for adolescents w…

    Stage

    Not phased

    Ages

    12 to 18

    Site

    Stanford University, Stanford, California

    Locations

    2 in total

    Run by

    Stanford University

    See if you can join NCT05563649 on ClinicalTrials.gov