Anatomic Stage IV Breast Cancer AJCC v8 Clinical Trials

44 studies are recruiting for anatomic stage iv breast cancer ajcc v8 in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Columbus, Ohio 8 Seattle, Washington 8 Duarte, California 7 Buffalo, New York 6 Jacksonville, Florida 6 New York, New York 6 St Louis, Missouri 6 Boston, Massachusetts 5 Houston, Texas 5 Irvine, California 5 Atlanta, Georgia 4 Aventura, Florida 4 Deerfield Beach, Florida 4 Los Angeles, California 4 Oklahoma City, Oklahoma 4 Pittsburgh, Pennsylvania 4 Rochester, Minnesota 4 Ann Arbor, Michigan 3 Aurora, Colorado 3 Baltimore, Maryland 3 Bloomington, Illinois 3 Canton, Illinois 3 Cape Girardeau, Missouri 3 Carthage, Illinois 3 City of Saint Peters, Missouri 3 Collierville, Tennessee 3 Columbus, Mississippi 3 Coral Gables, Florida 3 Creve Coeur, Missouri 3 Decatur, Illinois 3 Des Moines, Iowa 3 Eureka, Illinois 3 Flint, Michigan 3 Galesburg, Illinois 3 Grenada, Mississippi 3 Jonesboro, Arkansas 3 Kewanee, Illinois 3 Lansing, Michigan 3 Macomb, Illinois 3 Memphis, Tennessee 3 Miami, Florida 3 Mineola, New York 3 New Albany, Mississippi 3 New Haven, Connecticut 3 O'Fallon, Illinois 3 Ottawa, Illinois 3 Oxford, Mississippi 3 Pekin, Illinois 3 Peoria, Illinois 3 Peru, Illinois 3 Philadelphia, Pennsylvania 3 Phoenix, Arizona 3 Plantation, Florida 3 Portland, Oregon 3 Princeton, Illinois 3 Richmond, Virginia 3 Sacramento, California 3 San Diego, California 3 Springfield, Missouri 3 Springfield, Illinois 3

Studies, page 2

  1. Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

    This phase Ib trial tests the safety, side effects, and best dose of tumor treating fields therapy in combination with either cabozantinib or nab-paclitaxel and atezolizumab in treating patients with solid tumors involving the abdomen or thorax that have spread to other parts of the body (advanced)…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    M D Anderson Cancer Center, Houston, Texas
    Run by
    M.D. Anderson Cancer Center

    See if you can join NCT05092373 on ClinicalTrials.gov

  2. An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

    This clinical trial examines an investigational scan (64Cu-DOTA-trastuzumab positron emission tomography [PET]/magnetic resonance imaging [MRI]) in imaging patients with HER2+ breast cancer that has spread to the brain (brain metastasis). Diagnostic procedures, such as 64Cu-DOTA-trastuzumab PET/MRI…

    Stage
    Phase 4
    Ages
    18 and older
    Site
    City of Hope Medical Center, Duarte, California
    Run by
    City of Hope Medical Center

    See if you can join NCT05376878 on ClinicalTrials.gov

  3. Investigating the Feasibility and Acceptability of an Innovative Interdisciplinary Supportive Care Program: Couples Coping Together Against Cancer

    This study evaluates how useful and acceptable the components of the "Couples Coping Together Against Cancer", referred to as "The Program", are to the participants with cancer.

    Stage
    Not phased
    Ages
    18 and older
    Site
    City of Hope Medical Center, Duarte, California
    Run by
    City of Hope Medical Center

    See if you can join NCT07664579 on ClinicalTrials.gov

  4. Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial

    This phase II trial compares leuprolide to goserelin for reducing estrogen production by the ovaries in pre- or peri-menopausal women with breast cancer. Estrogen can cause the growth of breast cancer cells. Both leuprolide and goserelin lower the amount of estrogen made by the body. This may help …

    Stage
    Phase 2
    Ages
    18 and older
    Site
    University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan
    Run by
    University of Michigan Rogel Cancer Center

    See if you can join NCT07158021 on ClinicalTrials.gov

  5. Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer

    This study gathers information from the blood cells and tumor tissue during treatment with anti-HER2 therapies, such as trastuzumab, pertuzumab, lapatinib, or neratinib, in patients with HER2 positive stage I-IV breast cancer who are scheduled to start anti-HER2 therapy. The information gained from…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Mayo Clinic in Florida, Jacksonville, Florida
    Run by
    Mayo Clinic

    See if you can join NCT04517838 on ClinicalTrials.gov

  6. Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

    This phase II trial studies the effect of avapritinib in treating malignant solid tumors that have a genetic change (mutation) in CKIT or PDGFRA and have spread to nearby tissue or lymph nodes (locally advanced) or other places in the body (metastatic). Avapritinib may stop the growth of tumor cell…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    M D Anderson Cancer Center, Houston, Texas
    Run by
    M.D. Anderson Cancer Center

    See if you can join NCT04771520 on ClinicalTrials.gov

  7. 177Lu-DOTATATE for the Treatment of Stage IV or Recurrent Breast Cancer

    This phase II trial investigates how well 177Lu-DOTATATE works in treating patients with breast cancer that is stage IV or has come back (recurrent). 177Lu-DOTATATE may shrink or destroy the tumor or circulating breast cancer stem cells if they show evidence of the SSTR2. 177Lu-DOTATATE is a target…

    Stage
    Phase 2
    Ages
    18 to 100
    Site
    OHSU Knight Cancer Institute, Portland, Oregon
    Run by
    OHSU Knight Cancer Institute

    See if you can join NCT04529044 on ClinicalTrials.gov

  8. Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer

    This phase II trial tests how well propranolol and pembrolizumab work to cause tumor re-sensitization and therefore treatment in patients with triple negative breast cancer that has not responded to previous checkpoint inhibitor therapy (refractory), cannot be removed by surgery (unresectable) or h…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Emory University Hospital, Atlanta, Georgia
    Locations
    2 in total
    Run by
    Emory University

    See if you can join NCT05741164 on ClinicalTrials.gov

  9. Intravital Microscopy in Human Solid Tumors

    This study will investigate the tumor-associated vasculature of patients with solid tumors. The investigators will use a technology known as intravital microscopy (IVM) in order to visualize in real-time the vessels associated with solid tumors. The IVM observations may determine if an individual p…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Mayo Clinic Florida, Jacksonville, Florida
    Run by
    Mayo Clinic

    See if you can join NCT03823144 on ClinicalTrials.gov

  10. DiviTum®TKa: A Biomarker Assay for Efficacy in HR+ Breast Cancer Patients

    This study is being done to determine if there is a pattern associated with response to endocrine therapy alone and in combination with CDK4/6 inhibitor used for hormone receptor positive HER2 negative breast cancer.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Mayo Clinic in Florida, Jacksonville, Florida
    Run by
    Mayo Clinic

    See if you can join NCT06388122 on ClinicalTrials.gov

  11. Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer

    This phase II trial tests how well cemiplimab and transarterial radioembolization (TARE) with yttrium-90 (Y90) SIR-Spheres, registered trademark, works in treating breast cancer that has spread from where it first started (primary site) to the liver (metastatic). Immunotherapy with monoclonal antib…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    City of Hope Medical Center, Duarte, California
    Run by
    City of Hope Medical Center

    See if you can join NCT06860815 on ClinicalTrials.gov

  12. [18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast Cancer

    This clinical trial studies how well fluorine F 18 fluorthanatrace ([18F]FTT) positron emission tomography (PET) works in imaging patients with breast cancer that has spread from where it first started (primary site) to other places in the body (metastatic) who are receiving standard of care (SOC) …

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington
    Run by
    University of Washington

    See if you can join NCT06502691 on ClinicalTrials.gov

  13. Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer

    This phase II trial tests how well tamoxifen and pegylated liposomal doxorubicin works in treating patients with triple negative breast cancer that has spread from where it first started (primary site) to other places in the body (metastatic) or that has spread to nearby tissue or lymph nodes (loca…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Roswell Park Cancer Institute, Buffalo, New York
    Run by
    Roswell Park Cancer Institute

    See if you can join NCT06434064 on ClinicalTrials.gov

  14. High Dose Radiation Therapy With Pembrolizumab and Chemotherapy for the Treatment of Patients With PD-L1 Positive Metastatic Triple Negative Breast Cancer

    This phase II trial tests how well radiation therapy with pembrolizumab and chemotherapy (paclitaxel or nab-paclitaxel or carboplatin and gemcitabine) works in treating patients with PD-L1 positive triple negative breast cancer that has spread from where it first started (primary site) to other pla…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia
    Run by
    Emory University

    See if you can join NCT06492759 on ClinicalTrials.gov

  15. Living Well With Advanced Breast Cancer

    This study evaluates the use of supportive care in patients with advanced breast cancer to better understand what has helped them, what has been hard, and what kind of help they still need.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Ohio State University Comprehensive Cancer Center, Columbus, Ohio
    Run by
    Ohio State University Comprehensive Cancer Center

    See if you can join NCT07227038 on ClinicalTrials.gov

  16. Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer

    This early phase I trial studies the possible benefits and/or side effects of topical or oral minoxidil in treating endocrine therapy-induced hair loss (alopecia) in patients with stage I-IV breast cancer. Endocrine therapy-induced alopecia (EIA) is a distressing side effect that leads to reduced q…

    Stage
    EARLY_Phase 1
    Ages
    18 and older
    Site
    Ohio State University Comprehensive Cancer Center, Columbus, Ohio
    Run by
    Ohio State University Comprehensive Cancer Center

    See if you can join NCT05417308 on ClinicalTrials.gov

  17. Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative Breast Cancer

    This phase I trial tests the safety, side effects, and best dose of a personalized vaccine (tumor membrane vesicle or TMV vaccine) by itself and in combination with checkpoint inhibitor (pembrolizumab or ipilimumab) in treating patients with triple negative breast cancer. This vaccine is made by ta…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Grady Health System, Atlanta, Georgia
    Locations
    4 in total
    Run by
    Emory University

    See if you can join NCT06324240 on ClinicalTrials.gov

  18. Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

    This phase II trial tests how well craniospinal irradiation (CSI) using photon volumetric modulated arc radiotherapy (VMAT) works in treating patients with breast cancer or non-small cell lung cancer (NSCLC) that has spread from the original (primary) tumor to the cerebrospinal fluid and meninges (…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    City of Hope Medical Center, Duarte, California
    Locations
    2 in total
    Run by
    City of Hope Medical Center

    See if you can join NCT06910761 on ClinicalTrials.gov

  19. Biomarkers and Clinical Features of Metastatic Breast Cancer in Patients Treated With CDK4/6 Inhibitors

    This study investigates the clinical course of CDK4/6 inhibitor treated patients in the real-world setting among patients with breast cancer. CDK4/6 inhibitors may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Studying samples of blood, tissue, ascites or pl…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Roswell Park Cancer Institute, Buffalo, New York
    Run by
    Roswell Park Cancer Institute

    See if you can join NCT04526587 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.