Amyloidosis Clinical Trials in Rochester, Minnesota

5 studies are recruiting for amyloidosis in Rochester, Minnesota right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

   Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a sticky plaque-like substance that accumulates in different organs in the body and can cause damage to the organ. There are two ways that the TTR protein can fall a…

   Stage

   Phase 3

   Ages

   18 to 75

   Site

   Mayo Clinic - Rochester, Rochester, Minnesota

   Locations

   104 in total

   Run by

   Eidos Therapeutics, a BridgeBio company

   See if you can join NCT06563895 on ClinicalTrials.gov

2. A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Cyclophosphamide, Bortezomib, and Dexamethasone in Adult Participants With Newly Diagnosed Amyloid Light Chain (AL) Amyloidosis

   The study aims to evaluate the efficacy and safety of belantamab mafodotin in combination with cyclophosphamide, bortezomib, and dexamethasone in adult participants with newly diagnosed (ND) AL amyloidosis .

   Stage

   Phase 2

   Ages

   18 and older

   Site

   GSK Investigational Site, Rochester, Minnesota

   Locations

   5 in total

   Run by

   GlaxoSmithKline

   See if you can join NCT07224672 on ClinicalTrials.gov

3. A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

   Open-label Phase 1b/2 study with primary objective of this study is to evaluate the safety, tolerability and efficacy of AZD0120 in participants with light chain (AL) amyloidosis.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Research Site, Rochester, Minnesota

   Locations

   18 in total

   Run by

   Alexion Pharmaceuticals, Inc.

   See if you can join NCT07081646 on ClinicalTrials.gov

4. A Study Of Myocardial Stiffness In Amyloidosis With Magnetic Resonance Elastography

   This is a prospective case control study to determine the feasibility and utility of myocardial stiffness assessment by cardiac magnetic resonance elastography (MRE) in patients with cardiac amyloidosis.

   Stage

   Not phased

   Ages

   20 and older

   Site

   Mayo Clinic, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT07216469 on ClinicalTrials.gov

5. A Study Of MCG In Cardiac Amyloidosis

   The primary objective of this observational study is to evaluate the utility of magnetocardiography (MCG) in diagnosing and monitoring disease progression in patients with amyloidosis, and to assess its effectiveness in comparison to other modalities, such as ECG.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT07218705 on ClinicalTrials.gov