Alzheimer Disease Clinical Trials in Irvine, California

6 studies are recruiting for alzheimer disease in Irvine, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

   The main purpose of this study is to determine if participants who previously took donanemab get clinical benefit when they receive annual doses. For each participant, the study will last up to 2.5 years and will include 6 visits.

   Stage

   Phase 3

   Ages

   55 and older

   Site

   Irvine Clinical Research, Irvine, California

   Locations

   62 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT07602582 on ClinicalTrials.gov

2. A Study of LY4405094 in Healthy Participants and Participants With Alzheimer's Disease

   The purpose of this study is to see how safe LY4405094 is and to see how much and how quickly LY4405094 gets into the bloodstream. For healthy participants, the study also looks at how much LY4405094 gets into the fluid around the brain and lasts up to 13 weeks and will include a 4-day stay in the …

   Stage

   Phase 1

   Ages

   18 to 85

   Site

   Irvine Clinical Research, Irvine, California

   Locations

   18 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT07787182 on ClinicalTrials.gov

3. A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

   The primary purpose of this study is to evaluate the safety and tolerability of Zunveyl® over 12 weeks of routine clinical use in adults with mild to moderate Alzheimer's disease.

   Stage

   Phase 4

   Ages

   50 and older

   Site

   Progeny Psychiatric Clinic - Irvine, Irvine, California

   Locations

   22 in total

   Run by

   Alpha Cognition, Inc

   See if you can join NCT07633470 on ClinicalTrials.gov

4. A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease

   The purpose of this Master Protocol is to support multiple studies looking at safety and tolerability of different drugs in healthy participants and participants with Alzheimer's disease, and if they remove clumps of protein (amyloid plaque) in the brain in participants with Alzheimer's Disease. Pa…

   Stage

   Phase 1

   Ages

   18 to 85

   Site

   Irvine Clinical Research, Irvine, California

   Locations

   18 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT07787169 on ClinicalTrials.gov

5. A Study of LY3439539 in Participants With Alzheimer's Disease

   The purpose of this study is to see how LY3439539 affects certain proteins found in the spinal fluid of participants with Alzheimer's disease. Participation in the study will last approximately 9 months with visits about once a month.

   Stage

   Phase 1

   Ages

   50 to 85

   Site

   Irvine Clinical Research, Irvine, California

   Locations

   15 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT07598370 on ClinicalTrials.gov

6. Biomarker Exploration in Aging, Cognition and Neurodegeneration

   The purpose of this research study is to understand the factors that underlie changes in thinking and memory with increasing age. The investigators will test the usefulness of MRI, PET, and cognitive testing in detecting subtle changes in the brain that precede cognitive decline. An addendum to thi…

   Stage

   Phase 3

   Ages

   60 and older

   Site

   University of California, Irvine, Irvine, California

   Run by

   University of California, Irvine

   See if you can join NCT03860857 on ClinicalTrials.gov