Alcohol Drinking Clinical Trials

35 studies are recruiting for alcohol drinking in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Characterization Imaging Instruments in Alcoholics and Non-Alcoholics

   Background: - People with alcoholism have differences in their brains compared with healthy people. People who are dependent on alcohol also perform differently on behavioral tasks. Researchers want to find out more about these differences. They also want to see if these differences are related to …

   Stage

   Not phased

   Ages

   18 and older

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute on Alcohol Abuse and Alcoholism (NIAAA)

   See if you can join NCT02108080 on ClinicalTrials.gov

2. Alcohol, Breast Cancer, and Metabolism

   Alcohol consumption, even at low levels, has been associated with increased breast cancer risk, but the biological mechanisms underlying this relationship remain unclear. This study will examine whether breast tissue may locally metabolize alcohol by measuring alcohol-related compounds in paired bl…

   Stage

   Not phased

   Ages

   21 to 45

   Site

   Bevier Hall; University of Illinois at Urbana Champaign, Urbana, Illinois

   Run by

   University of Illinois at Urbana-Champaign

   See if you can join NCT07779967 on ClinicalTrials.gov

3. Nicotinic Receptor Genetic Variation and Alcohol Reward

   Background: People with the brain disease AUD (alcohol use disorder) have a serious problem with drinking. Researchers want to study how different people react to alcohol, and how genes affect this. They will focus on a nicotine receptor gene that may increase a person s AUD risk. Objectives: To se…

   Stage

   Phase 1

   Ages

   21 to 60

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute on Alcohol Abuse and Alcoholism (NIAAA)

   See if you can join NCT03294460 on ClinicalTrials.gov

4. Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT

   Among people living with HIV, heavy drinking increases the risk of heart disease and death. Studies suggest that alcohol changes the number and kind of bacteria in your gut and these changes increase the risk of heart disease and death. This randomized controlled trial will determine whether a pill…

   Stage

   Phase 2

   Ages

   18 to 89

   Site

   Vanderbilt University Medical Center, Nashville, Tennessee

   Run by

   Vanderbilt University Medical Center

   See if you can join NCT05288790 on ClinicalTrials.gov

5. Effects of Ketogenic Diet on Alcohol Intoxication

   The research study is being conducted to better understand the effects of ketosis on brain functioning and the acute effects of alcohol. Participants will be asked to undergo ~4 weeks of ketogenic diet intervention. The study involves three lab visits: Lab 1 before starting the diet, Lab 2 after ab…

   Stage

   Not phased

   Ages

   21 to 50

   Site

   Center for Studies of Addiction, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT07602270 on ClinicalTrials.gov

6. Alcohol and "Heat of the Moment" Sexual Decision Making

   HIV transmission remains a significant public health concern, especially among men who have sex with men (MSM). Condomless anal intercourse (CAI) continues to be the major route of transmission for MSM. Thus, to reduce the incidence of HIV, it is critical to identify how contextual risk factors inf…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Boston University Department of Psychological and Brain Sciences, Boston, Massachusetts

   Run by

   Boston University Charles River Campus

   See if you can join NCT05729256 on ClinicalTrials.gov

7. Alcohol & Men's Sexual Risk Behaviors

   This project extends the investigators' previous research regarding the intersecting risks of alcohol, sexual risk behavior (SRB), and sexual aggression (SA) in male drinkers who have sex with women by examining the mediating and moderating roles of both intrapersonal and interpersonal emotional fa…

   Stage

   Not phased

   Ages

   21 to 30

   Site

   Arizona State University, Phoenix, Arizona

   Run by

   Arizona State University

   See if you can join NCT06158880 on ClinicalTrials.gov

8. Behavioral and Functional Task Development, Implementation, and Testing

   Background: - Scientists know that alcohol use disorders affect brain structure. They want to know more about the effects of alcohol use disorders on a person s behavior. They want to develop tasks that can be done inside a scanner that can help them better understand these effects in later studies…

   Stage

   Not phased

   Ages

   18 to 65

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute on Alcohol Abuse and Alcoholism (NIAAA)

   See if you can join NCT02108054 on ClinicalTrials.gov

9. Reset Challenge: Reducing High-risk Drinking for Cancer Prevention

   This is a single-arm, non-randomized, prospective study to evaluate the feasibility and preliminary efficacy of a 30-day mobile Health (mHealth) Reset Challenge for reducing high-risk drinking.

   Stage

   Not phased

   Ages

   18 to 120

   Site

   University of Oklahoma Schusterman Center - Tulsa, Tulsa, Oklahoma

   Run by

   University of Oklahoma

   See if you can join NCT07591428 on ClinicalTrials.gov

10. Effects of Stereotype Threat on Impulsivity and Its Relation to Alcohol Use in African Americans: An fMRI Study

    The purpose of this study is to investigate the behavioral and neural correlates of stress exposure. Results from this study will enrich the understanding of how sociocultural, behavioral, and neural factors combine to influence alcohol use.

    Stage

    Not phased

    Ages

    21 to 35

    Site

    Icahn School of Medicine at Mount Sinai, New York, New York

    Run by

    Icahn School of Medicine at Mount Sinai

    See if you can join NCT05675332 on ClinicalTrials.gov

11. COVID-19 Pandemic Impact on Alcohol (PIA) - A Natural History Study

    Background: The SARS-CoV-2 virus has caused a pandemic infection called COVID-19. It is a global threat to people, communities, and health systems. Researchers are concerned about the mental health effects of the pandemic. They want to learn more about how it is affecting people s alcohol use and p…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    NIAAA Section on Human Psychopharmacology, Bethesda, Maryland

    Run by

    National Institute on Alcohol Abuse and Alcoholism (NIAAA)

    See if you can join NCT04391816 on ClinicalTrials.gov

12. Targeting Alcohol-Opioid Co-Use Among Young Adults Using a Novel MHealth Intervention

    The goal of this treatment development project is to develop and pilot an adaptive mobile health (mHealth) intervention that targets the co-use of alcohol and opioids in young adults.

    Stage

    Not phased

    Ages

    18 to 25

    Site

    Brown University Center for Alcohol and Addiction Studies, Providence, Rhode Island

    Run by

    Brown University

    See if you can join NCT07663448 on ClinicalTrials.gov

13. Text-Based Messaging Strategies for Preventing Subsequent Problematic Alcohol Use

    Binge drinking, and its health/social consequences are substantial public health concerns, with a high prevalence in young adults, especially in the US military. Alcohol consumption in the military is very high and normative, but there is zero tolerance for alcohol-related legal trouble, and Air Fo…

    Stage

    Not phased

    Ages

    18 and older

    Site

    JBSA Lackland, San Antonio, Texas

    Run by

    University of Virginia

    See if you can join NCT06318975 on ClinicalTrials.gov

14. Reducing Blood Pressure in Mid-life Adult Binge Drinkers

    This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers. Phase 2 is to examine the effect of 8-week aerobic exercise training on blood pressure, microvascular fu…

    Stage

    Not phased

    Ages

    50 to 64

    Site

    University of Texas at Arlington, Arlington, Texas

    Run by

    The University of Texas at Arlington

    See if you can join NCT05522075 on ClinicalTrials.gov

15. The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study

    Mobile health (mHealth) will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers. This program is inclusive of long term surveillance to downstage oral…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Memorial Sloan Kettering Cancer Center (All protocol activites), New York, New York

    Run by

    Memorial Sloan Kettering Cancer Center

    See if you can join NCT06535867 on ClinicalTrials.gov

16. Multi-Component Breath Alcohol Intervention Phase 3

    This is the third stage of a three-stage, NIH-funded study to develop and test a multi-modal intervention concerning blood/breath alcohol concentration for young adults who drink heavily. The multimodal intervention will be made up of brief telehealth counseling and psychoeducation and use of three…

    Stage

    Not phased

    Ages

    18 to 25

    Site

    Northeastern University, Boston, Massachusetts

    Run by

    Northeastern University

    See if you can join NCT06994962 on ClinicalTrials.gov

17. A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners

    The purpose of this study is to evaluate the efficacy of an adaptive web intervention (Partners Connect) on military spouse drinking behaviors (CPs) and service member help-seeking (SMs). The investigators want to identify for whom this intervention is most efficacious and on what drinking behavior…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Stanford University, Palo Alto, California

    Run by

    Stanford University

    See if you can join NCT05619185 on ClinicalTrials.gov

18. Motivations, Attitudes, and Perceptions Study

    The goal of this clinical trial is to compare the impact of providing participants with 1. A recently developed protocol for motivating bystanders to intervene to help others who are in sexual risk situations (Motivate-the-Bystander) alone 2. Motivate-the-Bystander with an alcohol component focused…

    Stage

    Not phased

    Ages

    18 to 25

    Site

    University of Nebraska-Lincoln, Lincoln, Nebraska

    Run by

    University of Nebraska Lincoln

    See if you can join NCT05873413 on ClinicalTrials.gov

19. Approach-Avoidance and Alcohol Challenge Study in PTSD

    Individuals with posttraumatic stress disorder (PTSD) have greater prevalence of alcohol use disorders (AUDs), with this comorbidity associated with worse illness outcomes, yet there remains limited mechanistic understanding of how PTSD confers risk for AUD. Understanding risk factors that associat…

    Stage

    Not phased

    Ages

    21 to 60

    Site

    University of Texas at Austin, Austin, Texas

    Run by

    University of Texas at Austin

    See if you can join NCT06002633 on ClinicalTrials.gov

20. Reducing Alcohol Exposed Pregnancies

    The goal of this clinical trial is to compare an active intervention versus a standard of care control in reducing alcohol use among pregnant women. The main questions it aims to answer are whether a motivational intervention can: 1. increase the proportion of women detected with a laboratory-confi…

    Stage

    Not phased

    Ages

    18 and older

    Site

    The University of Texas Health Science Center, Houston, Houston, Texas

    Run by

    New York University

    See if you can join NCT05766761 on ClinicalTrials.gov

21. MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

    The purpose of this study is to develop transcranial magnetic stimulation (TMS), specifically TMS at a frequency known as theta burst stimulation (TBS), to see how it affects the brain and changes the brain's response to alcohol-related pictures. TMS and TBS are stimulation techniques that use magn…

    Stage

    Not phased

    Ages

    21 to 65

    Site

    Medical University of South Carolina, Charleston, South Carolina

    Run by

    Medical University of South Carolina

    See if you can join NCT04998916 on ClinicalTrials.gov

22. Effects of Ketone Supplement and Alcohol on Brain Metabolism

    The research study is being conducted to better understand the effects of ketones and alcohol on brain functioning and brain metabolism. Participants will be asked to undergo three identical MRI visits after three single-dose interventions: (1) drink a ketone supplement drink, (2) drink an alcoholi…

    Stage

    Phase 2

    Ages

    21 to 65

    Site

    Center for Studies of Addiction, Philadelphia, Pennsylvania

    Run by

    University of Pennsylvania

    See if you can join NCT06815237 on ClinicalTrials.gov

23. The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in Normal Aging Adults Who Are High-Risk Alcohol Drinkers

    The goal of this pilot study is to explore a combination of two interventions: (1) a behavioral alcohol-reduction intervention using motivational interviewing, and (2) a blinded probiotic microbiome or placebo intervention. The study examines whether these interventions improve cognitive and neurop…

    Stage

    Not phased

    Ages

    65 to 84

    Site

    University of Miami, Miami, Florida

    Run by

    University of Miami

    See if you can join NCT07415707 on ClinicalTrials.gov

24. Ketone Ester Intervention in Alcohol Use Disorder

    The purpose of this research is to study how a nutritional ketone ester may effect brain function and alcohol consumption in regular alcohol users. The study will see how the brain responds, once after drinking the ketone ester and once after drinking a "placebo", which will look and taste the same…

    Stage

    Phase 2

    Ages

    21 to 65

    Site

    University of Pennsylvania Center for Studies of Addiction, Philadelphia, Pennsylvania

    Run by

    University of Pennsylvania

    See if you can join NCT04616781 on ClinicalTrials.gov

25. Acceptance and Commitment Therapy for HIV+ Hazardous Drinkers

    Alcohol consumption is a critical factor in HIV treatment that significantly contributes to poor treatment-related outcomes. Randomized clinical trials (RCTs) of alcohol interventions for people with HIV (PWH) have had limited success, perhaps due to an increasingly recognized co-morbitity of co-oc…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Syracuse University, Syracuse, New York

    Run by

    Syracuse University

    See if you can join NCT06648629 on ClinicalTrials.gov