Advanced Solid Tumors Clinical Trials in St Louis, Missouri

7 studies are recruiting for advanced solid tumors in St Louis, Missouri right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

    The goal of this clinical trial is to learn if the drug TUB-030 works to treat solid cancer in adults. The study will also explore the safety of TUB-030. The main questions it aims to answer are: To determine the safety and tolerability of TUB-030 To determine the maximum tolerated dose of TUB-030 …

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Washington University, St Louis, Missouri
    Locations
    20 in total
    Run by
    Tubulis GmbH

    See if you can join NCT06657222 on ClinicalTrials.gov

  2. A Study of PARG Inhibitor FORX-428 in Patients With Advanced Solid Tumors.

    The goal of this interventional study is to evaluate the safety and tolerability of escalating doses of FORX-428 as monotherapy in patients with select advanced solid tumors with BRCA1/2 mutations or other DDR deficiencies or high replication stress, and to determine the maximum tolerated dose (MTD…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Washington University St. Louis, St Louis, Missouri
    Locations
    8 in total
    Run by
    FoRx Therapeutics AG

    See if you can join NCT07356453 on ClinicalTrials.gov

  3. A Study of PHN-012 in Patients With Advanced Solid Tumors

    This first-in-human study will evaluate safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of PHN-012, a novel antibody-drug conjugate (ADC), in patients with advanced solid tumors.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    PHN-012-001 Site, St Louis, Missouri
    Locations
    26 in total
    Run by
    Pheon Therapeutics

    See if you can join NCT07127874 on ClinicalTrials.gov

  4. Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

    The primary goal of this study is to assess the safety and tolerability of mRNA-4359 administered alone and in combination with pembrolizumab or ipilimumab and nivolumab.

    Stage
    Phase 1
    Ages
    12 and older
    Site
    Washington University, St Louis, Missouri
    Locations
    39 in total
    Run by
    ModernaTX, Inc.

    See if you can join NCT05533697 on ClinicalTrials.gov

  5. A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

    The purpose of this study is to characterize the safety and tolerability of ALTA3263 in adults with advanced solid tumors with KRAS mutations.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Research Site, St Louis, Missouri
    Locations
    12 in total
    Run by
    Alterome Therapeutics, Inc.

    See if you can join NCT06835569 on ClinicalTrials.gov

  6. JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration

    This study is to evaluate the safety and tolerability of pan-KRAS inhibitor JAB-23E73 in adult participants with advanced solid tumors

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Washington University, St Louis, Missouri
    Locations
    4 in total
    Run by
    Jacobio Pharmaceuticals Co., Ltd.

    See if you can join NCT06973564 on ClinicalTrials.gov

  7. A Clinical Study of YL205 in Patients With Advanced Solid Tumors

    This study is a multicenter, open-label, phase I/II study of YL205 in China to evaluate the safety, tolerability, PK characteristics and preliminary efficacy of YL205 in the following selected patients with advanced solid tumors.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Washington University School of Medicine - Center for advanced Medicine, St Louis, Missouri
    Locations
    43 in total
    Run by
    MediLink Therapeutics (Suzhou) Co., Ltd.

    See if you can join NCT06459973 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.