Advanced Melanoma Clinical Trials in Houston, Texas

4 studies are recruiting for advanced melanoma in Houston, Texas right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

   This is a randomized, controlled, multicenter, open-label Phase 3 clinical study comparing VO in combination with nivolumab versus Physician's Choice treatment for patients with unresectable Stage IIIb-IV cutaneous melanoma whose disease progressed on an anti PD-1 and an anti-CTLA-4 containing regi…

   Stage

   Phase 3

   Ages

   12 and older

   Site

   The University of Texas MD Anderson Cancer Center, Houston, Texas

   Locations

   81 in total

   Run by

   Replimune, Inc.

   See if you can join NCT06264180 on ClinicalTrials.gov

2. IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

   To find the highest tolerable dose of IACS-6274 that can be given alone, in combination with bevacizumab and paclitaxel, or in combination with capivasertib to patients who have solid tumors. The safety and tolerability of the study drug(s) will also be studied.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   M D Anderson Cancer Center, Houston, Texas

   Run by

   M.D. Anderson Cancer Center

   See if you can join NCT05039801 on ClinicalTrials.gov

3. A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma

   The purpose of this study is to test whether the combination of fianlimab, cemiplimab, and ipilimumab is a safe and effective treatment that causes few or mild side effects for locally advanced or metastatic, unresectable, refractory melanoma.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   MD Anderson Cancer Center (Data Collection Only), Houston, Texas

   Locations

   12 in total

   Run by

   Memorial Sloan Kettering Cancer Center

   See if you can join NCT06594991 on ClinicalTrials.gov

4. Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

   The purpose of this study is to evaluate the efficacy and safety of tebentafusp-based regimens, including tebentafusp monotherapy and in combination with anti-PD1 vs investigator choice (including clinical trials of investigational agents, salvage therapy per local standard of care [SoC], best supp…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Houston Methodist Hospital/Houston Methodist Cancer Center, Houston, Texas

   Locations

   82 in total

   Run by

   Immunocore Ltd

   See if you can join NCT05549297 on ClinicalTrials.gov